Top Senior Machine Learning Jobs in Denver & Boulder, CO

Reposted 22 Hours AgoSaved
Remote
Colorado
Senior level
Senior level
Big Data • Analytics • Business Intelligence • Big Data Analytics
The Machine Learning Engineer will develop software solutions, optimize data pipelines, and deploy machine learning models using cloud platforms and best practices.
Top Skills: AzureAzuremlDatabricksDockerMlflowPythonSpark
Reposted 22 Hours AgoSaved
In-Office or Remote
Colorado
140K-190K Annually
Senior level
140K-190K Annually
Senior level
Fintech • Machine Learning • Payments • Software • Financial Services
Lead end-to-end ML projects for fraud detection: develop, deploy, monitor, and iterate production models and experimentation frameworks. Improve model performance, build scalable ML pipelines, collaborate with Product/Engineering/Risk, and champion testing, documentation, and model-monitoring best practices to ensure robust, high-impact solutions.
Top Skills: Ml LibrariesPythonSparkSQL
Reposted 22 Hours AgoSaved
Remote
Colorado
128K-267K Annually
Senior level
128K-267K Annually
Senior level
AdTech • Digital Media • Information Technology • Other
Design, build, and deploy high-throughput ML and LLM-powered personalization and agentic systems at consumer scale. Process petabyte-scale data, optimize real-time inference, implement resilient fallback paths, and balance latency, cost, and model quality while collaborating across engineering and product teams.
Top Skills: HadoopHugging FaceJavaOnnx RuntimePythonPyTorchScikit-LearnSparkTensorFlowTensorrt-LlmTritonVllm
Reposted 2 Days AgoSaved
Remote
Colorado
118K-171K Annually
Senior level
118K-171K Annually
Senior level
Beauty • Cloud • Fintech • Marketing Tech • Payments • Productivity • Software
Design, build, and productionize ML and AI systems (LLMs, embeddings, recommendations, forecasting). Develop end-to-end ML workflows, scalable data pipelines, semantic models, and CI/CD for ML. Collaborate with product and engineering, mentor engineers, and influence platform architecture and standards.
Top Skills: Ci/CdDatabricksEmbeddingsForecasting ModelsLlmsMl FrameworksMlopsPythonRecommendation SystemsSemantic LayerSnowflakeSnowflake CortexSQL
Reposted 2 Days AgoSaved
Remote
Colorado
191K-225K Annually
Senior level
191K-225K Annually
Senior level
Real Estate • Travel • PropTech
Lead development and productionization of large-scale ranking and personalization ML systems. Build data pipelines, features, and models (batch and real-time), collaborate cross-functionally, run experiments, and improve infrastructure for search, recommendation, and marketplace optimization.
Top Skills: AirflowC++HiveJavaKafkaKubernetesPythonPyTorchScalaSparkTensorFlow
Reposted 2 Days AgoSaved
Remote
Colorado
180K-230K Annually
Senior level
180K-230K Annually
Senior level
Software • Energy
The role involves developing and deploying machine learning models for forecasting within the Camus platform, requiring collaboration and technical depth in ML.
Top Skills: AirflowDatabricksPandasPythonPyTorchScikit-LearnSparkStatsmodels
Reposted 2 Days AgoSaved
Remote or Hybrid
Colorado
Senior level
Senior level
Artificial Intelligence • Fintech • Software • Financial Services
The Senior Machine Learning Engineer will build and own production ML systems, manage end-to-end workflow, debug issues, and mentor others.
Top Skills: JaxPythonPyTorch
Reposted 2 Days AgoSaved
Remote
Colorado
Senior level
Senior level
Cloud • Software
Design, build, test, deploy, and maintain production AI capabilities (agents, workflows, models, MCP servers, APIs) across a SaaS dental platform. Train and operate ML models, implement RAG and vector DB solutions, use AI-assisted tools, collaborate in design and code reviews, and support production reliability and monitoring.
Top Skills: Agentic Ai FrameworksAmazon BedrockAnthropicAPIsClaude CodeCloud-Native ArchitecturesConversational AiCursorDistributed SystemsEmbeddingsGithub CopilotLanggraphLlmsMcp ServersMlopsOpenaiPrompt EngineeringPythonRetrieval-Augmented Generation (Rag)Speech TechnologiesVector Databases
Reposted 2 Days AgoSaved
In-Office
Colorado
115K-175K Annually
Senior level
115K-175K Annually
Senior level
Information Technology • Consulting
Lead Machine Learning Engineers at CapTech design and implement data-driven solutions, build machine learning systems, mentor teams, and analyze large datasets.
Top Skills: Amazon RdsAWSAzureAzure SqlDatabricksDockerGCPNoSQLPythonScalaSnowflakeSparkSQL
Reposted 2 Days AgoSaved
In-Office
Colorado
140K-185K Annually
Senior level
140K-185K Annually
Senior level
Information Technology • Consulting
Lead Machine Learning Engineer at CapTech focuses on designing and deploying scalable machine learning systems and providing technical leadership.
Top Skills: Amazon RdsAzure SqlDatabricksDockerNoSQLPythonScalaSnowflakeSparkSQL
Reposted 2 Days AgoSaved
In-Office
Colorado
90K-200K Annually
Senior level
90K-200K Annually
Senior level
Information Technology • Consulting
Lead Machine Learning Engineer at CapTech will design data-driven solutions, implement machine learning systems, and provide technical leadership. Responsibilities include collaborating with clients and teams, analyzing large datasets, and managing ML practices.
Top Skills: Amazon RdsAzure SqlDatabricksDockerNoSQLPythonScalaSnowflakeSparkSQL
Reposted 2 Days AgoSaved
Remote
Colorado
Senior level
Senior level
Software
Seeking a Senior Machine Learning Engineer to design and implement ML systems, optimize deployment, and collaborate with data teams, focusing on scalability and performance.
Top Skills: AirflowArgoAWSDatadogGCPIllamaindexKerasKubeflowKubernetesLangchainLanggraphMs AzurePythonPyTorchTensorFlow
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Reposted 2 Days AgoSaved
In-Office
Colorado
127K-231K Annually
Senior level
127K-231K Annually
Senior level
Biotech
Lead the scientific direction and machine learning development for climate modeling. Manage model training, evaluation, and collaboration across teams to develop predictive systems based on hydrology and climate data.
Top Skills: AWSPythonPyTorch
Reposted 3 Days AgoSaved
In-Office or Remote
Colorado
111K-222K Annually
Senior level
111K-222K Annually
Senior level
Fitness • Healthtech • Retail • Pharmaceutical
The Senior Machine Learning Engineer will build and optimize ML systems for CRM marketing, collaborating with cross-functional teams to impact customer engagement and product functionality.
Top Skills: AirflowBigQueryKafkaKubeflowNode.jsPythonPyTorchReactSnowflakeSparkSQLTensorFlowVertex
Reposted 3 Days AgoSaved
Remote
Colorado
Senior level
Senior level
Information Technology • Software
The Senior AI/ML Engineer will develop AI systems for enterprise decision-making, focusing on LLMs and real-time data processing. Responsibilities include building detection systems, insight engines, evaluation frameworks, and collaborating with engineers to ensure robust AI product engineering.
Top Skills: AutogenAws BedrockAzure OpenaiCrewaiGcp Vertex AiKotlinLangchainLlamaindexLlmsPythonTypescript
4 Days AgoSaved
Remote
Colorado
150K-180K Annually
Senior level
150K-180K Annually
Senior level
AdTech • Marketing Tech
Designs, builds, deploys, and operates production AI/ML and LLM systems. Responsibilities include developing RAG pipelines, fine-tuning and evaluating models, managing end-to-end MLOps lifecycles, establishing monitoring and governance practices, mentoring engineers, and leading complex cross-functional client and internal initiatives.
Top Skills: Amazon BedrockAmazon SagemakerAWSAzureAzure MlCi/CdDatabricksEmbeddingsHuggingfaceLlmsMlopsPythonPyTorchRagSnowflakeSQLVector Search
Reposted 4 Days AgoSaved
Remote
Colorado
Senior level
Senior level
Artificial Intelligence • Information Technology • Software
The Senior ML Engineer will develop and deploy full-stack AI solutions, manage LLM integration, and collaborate closely with defense clients to enhance real-world applications in secure environments.
Top Skills: Ai Coding ToolsAWSDockerKubernetesLanggraphLlm OpsOpenai Agents Sdk
Reposted 4 Days AgoSaved
In-Office
Colorado
127K-193K Annually
Senior level
127K-193K Annually
Senior level
Hardware • Database • Defense
Design, train, and optimize high-performance ML/AI models and inference pipelines for remote sensor (OPIR) data. Integrate models into production Linux-based systems, collaborate with C++ and systems engineers, apply rigorous software engineering and Agile practices, and support missile warning, defense, and sensor-fusion applications.
Top Skills: LinuxPythonPyTorchScikit-LearnTensorFlow
Reposted 4 Days AgoSaved
Remote
Colorado
230K-270K Annually
Senior level
230K-270K Annually
Senior level
Software
Lead design, development, and production deployment of ML and algorithmic solutions. Own end-to-end ML systems, support distributed production reliability, communicate tradeoffs, and apply generative AI, LLM fine-tuning, RAG, and agentic techniques to product problems.
Top Skills: Agentic AiHuggingfaceKubernetesLlmsPyTorchRag PipelinesScikit-LearnSpacy
Reposted 4 Days AgoSaved
Remote
Colorado
Senior level
Senior level
Internet of Things
Build and productionize AI systems for logistics: multi-agent copilots, forecasting/optimization models, evaluation and observability, continuous learning loops, and operational reliability. Mentor engineers and make build-vs-rule tradeoffs while shipping high-impact ML services.
Top Skills: Amazon BedrockAnthropicAzure OpenaiBrowser AutomationDocument UnderstandingFastapiFeature StoresLangchainLanggraphMcpMlopsMulti-Agent OrchestrationOpenaiPythonRag (Retrieval-Augmented Generation)Streaming SystemsTool/Function-Calling
Reposted 4 Days AgoSaved
Remote
Colorado
184K-270K Annually
Senior level
184K-270K Annually
Senior level
Financial Services
Lead and execute ML/AI strategy, design and deploy production-grade ML and GenAI solutions, mentor MLEs, collaborate with cross-functional teams, and build scalable, secure ML/LLM platforms and inference pipelines to drive business impact.
Top Skills: Apache AirflowBayesian Contextual Multi-Armed BanditsCausal Meta-LearnerDatabricksDatabricks Model ServingDeep LearningDvcFlinkGraph Neural NetworksGraphQLGrpcKafkaKinesisKubeflowLlmsMl/Llm OpsMlflowModel QuantizationModel VersioningParameter-Efficient Fine-TuningQuantization-Aware Fine-TuningRayReinforcement LearningSnowflakeSparkTransformersXgboost
Reposted 5 Days AgoSaved
Remote
Colorado
128K-204K Annually
Senior level
128K-204K Annually
Senior level
Software
Design, prototype, and ship LLM- and agent-powered AI features for observability. Rapidly iterate with real users, integrate AI workflows with tooling and alerting, collaborate cross-functionally, and ensure scalable, production-ready solutions in cloud-native environments.
Top Skills: AWSAzureClaude OpusDockerGCPGemini 3 ProGenaiGpt-CodexGrafanaGrafana CloudKubernetesLlmsModel Fine-TuningPrompt EngineeringTerraform
Reposted 5 Days AgoSaved
Remote
Colorado
600K-1M Annually
Senior level
600K-1M Annually
Senior level
News + Entertainment
Lead ML technical strategy for Live Ads, designing and deploying forecasting, targeting, bidding, auction, and yield-optimization models. Build and evaluate large-scale production ML systems, create online/offline evaluation frameworks, partner with product to set objectives and trade-offs, and communicate results to stakeholders and leadership.
Top Skills: JavaPythonScala
Reposted 5 Days AgoSaved
Remote
Colorado
466K-750K Annually
Senior level
466K-750K Annually
Senior level
News + Entertainment
Lead ML initiatives to improve Sales productivity and automation: define roadmap, design and deploy production ML models and AI agents, build measurement pipelines with analytics engineers, iterate from performance and seller feedback, and act as senior technical partner across product, engineering, and Sales to drive measurable revenue impact.
Top Skills: PythonSQL
7 Days AgoSaved
In-Office
Colorado
157K-290K Annually
Senior level
157K-290K Annually
Senior level
Analytics • Consulting
Lead and oversee enterprise ML and statistical modeling efforts, build and mentor data science teams, ensure model governance and compliance, collaborate cross-functionally to deliver scalable AI solutions that drive business outcomes, and advance research and adoption of cutting-edge ML methods.
Top Skills: Aws SagemakerAzure MlDatabricksMlopsPythonSQL
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