Top Senior Machine Learning Jobs in Denver & Boulder, CO

Reposted 10 Days AgoSaved
Remote
Colorado
250K-300K Annually
Senior level
250K-300K Annually
Senior level
Automotive • Insurance • Machine Learning • Mobile • Software
Lead a multidisciplinary team to design, deploy, and optimize ML-driven bidding systems and measurement for a nine-figure marketing budget. Drive experimentation, partner strategy, media-mix optimization, and end-to-end measurement while aligning Marketing, Analytics, Engineering, and Product to improve marketing ROI and scale performance.
Top Skills: AWSMachine LearningMobile Telematics
12 Days AgoSaved
Remote
Colorado
Senior level
Senior level
Angel or VC Firm • Automotive • Transportation
Lead end-to-end deployments of AI for hotel revenue teams: integrate PMS/CRS/RMS, ship ML/optimization models and agentic workflows, validate recommendations with revenue managers, define metrics, drive adoption, and hire/mentor the forward deployed engineering team.
Top Skills: Agentic AiAmadeus AcrsAmadeus BiAWSAzureDuettoGCPHtngIdeasKalibriLighthouseMachine LearningModel Context Protocol (Mcp)Opentravel Alliance (Ota)Optimization ToolingOracle Hospitality Integration Platform (Ohip)Oracle OperaPythonRagRevenue AnalyticsSabre SynxisSQLStrUniversal Commerce Protocol (Ucp)
14 Days AgoSaved
Remote
Colorado
466K-750K Annually
Senior level
466K-750K Annually
Senior level
News + Entertainment
Conduct research and develop identity and probabilistic-matching models for Netflix's ad-supported tier. Apply ML and statistical methods, ensure privacy-preserving solutions (differential privacy, anonymization), prototype and deploy production models, deliver datasets and tools, and partner with product, engineering, and business stakeholders to measure and drive impact.
Top Skills: AnonymizationDifferential PrivacyLookalike AlgorithmsMachine LearningProbabilistic MatchingPythonSQLStatistical Modeling
Reposted 14 Days AgoSaved
Remote
Colorado
Senior level
Senior level
Big Data • Food • Mobile • Payments
The Staff Machine Learning Engineer will lead ML systems development for personalization and ranking, design architectures, and mentor team members, ensuring reliable operations at scale.
Top Skills: Ai ToolsData PipelinesDistributed SystemsLlm ToolsMachine LearningMl Infrastructure
Reposted 14 Days AgoSaved
Remote
Colorado
Senior level
Senior level
Artificial Intelligence • Big Data • Internet of Things • Software
The Machine Learning Engineer will work on unstructured data classification and clustering, utilizing their expertise in AI systems and various programming languages.
Top Skills: Ai SystemsC++Data Visualization ToolsJavaMachine LearningMatlabPythonSQL
Reposted 14 Days AgoSaved
Remote
Colorado
5-5 Annually
Senior level
5-5 Annually
Senior level
Artificial Intelligence • Big Data • Internet of Things • Software
The Senior Machine Learning Engineer will utilize deep experience and insights to enhance communication and digital interactions through advanced machine learning tools and algorithms, focusing on unstructured data.
Top Skills: C++Data VisualizationJavaMachine LearningPythonSQL
Reposted 16 Days AgoSaved
Remote or Hybrid
Colorado
230K-350K Annually
Senior level
230K-350K Annually
Senior level
Big Data • Information Technology • Software • Database • Analytics
Lead machine learning initiatives, oversee product development, improve execution pace, enhance team reliability, and foster team growth at Hightouch.
Top Skills: DatabricksLlmsMachine LearningSnowflake
17 Days AgoSaved
Remote
Colorado
160K-190K Annually
Senior level
160K-190K Annually
Senior level
Software
Act as the technical lead in enterprise sales: run technical discovery, design and deliver customized demos and POCs, assess API/cloud/model fit, address technical objections, support contract negotiations, and relay product feedback to engineering while staying current on AI/ML trends.
Top Skills: Ai/MlAPIsCloud InfrastructureLlmsMachine LearningOpenrouter
Reposted 22 Days AgoSaved
Remote
Colorado
150K-215K Annually
Senior level
150K-215K Annually
Senior level
Artificial Intelligence • Machine Learning • Software • Defense
Develop scalable machine learning services for data enrichment, managing the ML lifecycle from model training to deployment, and ensuring performance and reliability standards.
Top Skills: Hugging FaceKubernetesOnnxPyTorchRayTensorFlowTensorrtVllm
Reposted 18 Days AgoSaved
Remote
Colorado
220K-250K Annually
Senior level
220K-250K Annually
Senior level
Events • Greentech • Logistics • Software • Transportation • Travel
Lead design and production deployment of ML models focused on pricing, availability, forecasting, and optimization. Build data infrastructure, governance, testing/monitoring, and dashboards. Partner with executives and cross-functional teams, mentor others, and establish scalable data-science practices and experimentation frameworks.
Top Skills: LlmsMachine LearningNlpPythonRSQL
19 Days AgoSaved
Remote
Colorado
Senior level
Senior level
eCommerce
Lead development and deployment of cutting-edge ML models for pricing, design and analyze experiments, collaborate with product and engineering, present findings to stakeholders, and lead technical projects to influence team output and business metrics.
Top Skills: AIMachine LearningMachine Learning AlgorithmsPython
Reposted 19 Days AgoSaved
In-Office or Remote
Colorado
180K-220K Annually
Senior level
180K-220K Annually
Senior level
Marketing Tech
Lead the development and implementation of machine learning solutions, managing a team to drive strategic decisions and innovative business outcomes.
Top Skills: Artificial IntelligenceMachine LearningStatistical Techniques
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Reposted 20 Days AgoSaved
Remote
Colorado
Senior level
Senior level
Artificial Intelligence • Software • Analytics
As a Senior Machine Learning Engineer, you will enhance diffusion models, conduct research, collaborate on system implementations, and communicate findings effectively.
Top Skills: AIAWSAzureDeep LearningDiffusion ModelsGansGCPMachine LearningMultimodal LlmsPyTorchVaes
Reposted 20 Days AgoSaved
Remote
Colorado
Senior level
Senior level
Manufacturing
Design, build, and deploy machine learning systems for controlling quantum processors. Develop reinforcement learning and Bayesian methods for QEC calibration, and work cross-functionally with product and R&D teams.
Top Skills: Deep LearningMachine LearningPythonReinforcement Learning
Reposted 21 Days AgoSaved
In-Office or Remote
Colorado
225K-260K Annually
Senior level
225K-260K Annually
Senior level
Robotics
Develop and scale machine learning training systems for robotics data, optimize training pipelines, and collaborate with ML researchers to enhance autonomy models.
Top Skills: Distributed Training FrameworksMachine LearningNeural NetworksPython
Reposted 22 Days AgoSaved
In-Office or Remote
Colorado
Senior level
Senior level
Insurance
Senior individual contributor responsible for leading pet/P&C insurance pricing model development (GLMs and ML), owning end-to-end projects, performing EDA and root-cause analysis, communicating results to stakeholders, and mentoring junior team members.
Top Skills: GlmMachine LearningPythonRegression ModelingSQLStatistical Inference
Reposted 22 Days AgoSaved
Remote
Colorado
160K-210K Annually
Senior level
160K-210K Annually
Senior level
Artificial Intelligence • Fintech • Machine Learning • Software • Financial Services
Embed with clients to gather requirements and design AI-driven solutions for fraud and fincrime. Architect, train, evaluate, and deploy custom AI agents and workflows, optimize model performance, establish risk metrics and evaluation pipelines, and collaborate with engineering/product teams to scale into production.
Top Skills: Ai AgentsEvaluation PipelinesFine-TuningMachine LearningModel DeploymentPrompt EngineeringPythonSQL
Reposted 22 Days AgoSaved
In-Office or Remote
Colorado
Senior level
Senior level
Fintech • Financial Services
Lead end-to-end research applying advanced ML/DL (transformers, GNNs, RL, ensembles) to generate alpha across digital asset markets, build production-grade pipelines, prevent leakage/overfitting, analyze microstructure and on-chain data, and mentor junior researchers.
Top Skills: Attention MechanismsC++Deep LearningEnsemble MethodsGraph Neural NetworksLightgbmMachine LearningOn-Chain DataPythonReinforcement LearningRustTransformersXgboost
Reposted 22 Days AgoSaved
Remote
Colorado
Senior level
Senior level
Artificial Intelligence • Healthtech • Machine Learning
As Director of AI/ML, lead the ML organization, set technical vision, mentor a high-performing team, and contribute to model development and production deployment.
Top Skills: Data WarehousingDatabricksEhrFhirHl7Machine LearningRedshiftSnowflake
Reposted 22 Days AgoSaved
Remote
Colorado
144K-299K Annually
Senior level
144K-299K Annually
Senior level
AdTech • Digital Media • Information Technology • Other
Conduct ML research for query understanding, ranking, clustering, and AI-powered search. Prototype and productionize algorithms, define data and evaluation requirements, design scalable systems, collaborate with engineers, run experiments, and publish patents/papers to integrate state-of-the-art ML into Yahoo Search products.
Top Skills: Deep LearningJavaMachine LearningNatural Language ProcessingPythonScalaSearch Ranking
Reposted 3 Hours AgoSaved
Remote
Colorado
156K-229K Annually
Senior level
156K-229K Annually
Senior level
Productivity • Software • Conversational AI
The Machine Learning Engineer will develop and maintain scalable ML systems, collaborate across teams, and innovate solutions for real-time applications to enhance customer experiences.
Top Skills: AirflowAWSAzureDockerDynamoDBEmrFlinkGCPJavaKafkaKubeflowKubernetesMetaflowMlflowOpensearchPythonSagemakerSnowflakeSparkSQL
Reposted 19 Hours AgoSaved
Remote or Hybrid
Colorado
160K-240K Annually
Senior level
160K-240K Annually
Senior level
Artificial Intelligence
Design, train, and deploy scalable ML models (generative, classification, regression). Define feature roadmaps, collaborate with engineering to implement code and APIs, adapt ML methods for distributed/GPU environments, and create evaluation/annotation programs for fine-tuning and performance measurement.
Top Skills: Apache BeamSparkApi DevelopmentDistributed SystemsGpuPythonPyTorchTensorFlow
Reposted 22 Hours AgoSaved
Remote or Hybrid
Colorado
180K-250K Annually
Senior level
180K-250K Annually
Senior level
Artificial Intelligence • Professional Services • Consulting • Automation
Design and deploy production recommendation and retrieval engines, build data orchestration pipelines for multiple modalities, implement agentic workflow frameworks, and prototype, optimize, and scale models with monitoring, governance, and low-latency SLAs.
Top Skills: AirflowSparkEmbeddingsKafkaKubernetesLangchainPythonPyTorchRagRetrieval LibrariesServerlessTensorFlowTransformer-Based Models
Reposted 22 Hours AgoSaved
Remote
Colorado
221K-405K Annually
Senior level
221K-405K Annually
Senior level
Social Media • Software
As a Senior Machine Learning Engineer, you will design and maintain ML systems for content recommendations, search, and spam detection, while augmenting user experience and system performance.
Top Skills: BigQueryGoPostgresPythonPyTorchRay
Reposted 22 Hours AgoSaved
Remote
Colorado
180K-225K Annually
Senior level
180K-225K Annually
Senior level
Big Data • HR Tech • Mobile • Software • Database
Lead design, development, and productionization of advanced ML models and data pipelines. Drive architecture, experimentation, validation, and best practices while mentoring ML engineers and delivering scalable, business-driving AI solutions.
Top Skills: BertConvolutional Neural Networks (Cnn)Generative Adversarial Networks (Gan)LstmNltkPyTorchRecurrent Neural Networks (Rnn)Scikit-LearnSpacyTensorFlow
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