Top Senior Data Science Jobs in Denver & Boulder, CO

YesterdaySaved
Easy Apply
Remote
Colorado
Easy Apply
153K-180K Annually
Senior level
153K-180K Annually
Senior level
Artificial Intelligence • Fintech • Healthtech • Software
Lead product analytics efforts by designing and evaluating experiments, building dashboards, and producing statistical insights. Partner with product, design, and engineering to measure product success, identify optimization opportunities, and embed ML-driven personalization into the product.
Top Skills: DbtHexLookerPythonSQL
Reposted 7 Days AgoSaved
Easy Apply
Remote
Colorado
Easy Apply
236K-295K Annually
Senior level
236K-295K Annually
Senior level
Artificial Intelligence • Enterprise Web • Information Technology • Productivity • Sales • Software • Database
Lead product analytics to inform strategy and optimize user experience: translate business questions into analysis, build reliable analytics infrastructure, run A/B tests and ML/statistical analyses, track funnels and cohorts, support 0-to-1 product launches, and communicate actionable insights to cross-functional teams.
Top Skills: A/B TestingAmplitudeHeapLookerMachine LearningMixpanelPythonRSASSQLStatistical Analysis
9 Days AgoSaved
Hybrid
Colorado
Senior level
Senior level
eCommerce • Mobile • Payments
Lead data science initiatives across core business domains: collaborate with stakeholders and engineers, analyze large datasets, design experiments, build and productionize statistical and ML models, harden pipelines, monitor performance, and mentor teams to drive data-informed decisions.
Top Skills: Graph Data SchemasMlopsPysparkPythonRSparkSQL
17 Days AgoSaved
Hybrid
Colorado
99K-232K Annually
Senior level
99K-232K Annually
Senior level
Artificial Intelligence • Professional Services • Business Intelligence • Consulting • Cybersecurity • Generative AI
Lead teams applying advanced data science and machine learning to large-scale claims, clinical, and member data to generate actionable insights that reduce cost of care and improve population health. Manage client relationships, mentor staff, ensure project delivery and quality, develop payer-focused analytics products, present findings to senior stakeholders, and promote continuous improvement and knowledge sharing.
Top Skills: Claims DataClinical DataCms Star RatingsMachine LearningNcqa HedisNlpSocial Determinants Of Health (Sdoh) Data
19 Days AgoSaved
Easy Apply
Remote
Colorado
Easy Apply
207K-244K Annually
Senior level
207K-244K Annually
Senior level
Artificial Intelligence • Blockchain • Fintech • Financial Services • Cryptocurrency • NFT • Web3
Lead end-to-end pricing experimentation and strategy for consumer and business products. Design and analyze A/B tests, build pricing models and production-grade data pipelines, partner cross-functionally, and present actionable recommendations to senior leadership.
Top Skills: Generative AiPythonRSQL
3 Days AgoSaved
Remote
Colorado
192K-228K Annually
Senior level
192K-228K Annually
Senior level
Healthtech • Social Impact • Software • Telehealth
Owner of analytics for EHR, revenue cycle, and operations: design and run experiments, analyze financial and operational metrics, investigate billing and account issues, and deliver actionable insights to Product, Operations, Finance, and Customer Experience to improve accuracy, reduce friction, and support growth.
Top Skills: EhrHexLookerPythonRevenue Cycle ManagementSQLTableau
YesterdaySaved
Remote
Colorado
185K-231K Annually
Senior level
185K-231K Annually
Senior level
Artificial Intelligence • Software • Analytics • Business Intelligence
Lead and build Neural Earth's geospatial data science function: design and deploy Python-based geospatial models, architect production geospatial data pipelines, validate reproducible methods, translate scientific outputs into customer-ready products, and manage and mentor at least one direct report while advising customers and stakeholders.
Top Skills: CogGdalGeopandasGeoparquetGeotiffNetcdfPythonRasterioShapelyXarray
Reposted YesterdaySaved
Remote
Colorado
150K-195K Annually
Senior level
150K-195K Annually
Senior level
Software • Cryptocurrency • Web3
Partner with Marketing as the embedded data science lead to build marketing measurement, attribution, LTV/ROAS/CAC models, run experiments, analyze the full funnel, create forecasts and dashboards, and influence channel strategy and budget allocation.
Top Skills: Ad PlatformsAppsflyerGoogle AnalyticsLookerMmpPythonRSQLTableau
Reposted YesterdaySaved
Remote
Colorado
255K-298K Annually
Senior level
255K-298K Annually
Senior level
Consumer Web • Other • Social Media • Software
As the Staff Data Scientist, you will lead the data science function, driving strategy, mentoring peers, and shaping product direction through advanced analytics and experimentation.
Top Skills: PythonSQL
Reposted 2 Days AgoSaved
Remote
Colorado
Senior level
Senior level
Big Data • Food • Mobile • Payments
Lead company-level measurement and causal strategy, define MAU×ARPU metrics and semantic mart, set scientific standards for experimentation and analysis, own strategic models (MMM, elasticity, forecasting), partner with engineering to productionize analytics, and raise org-wide scientific maturity through governance, templates, and upskilling.
Top Skills: DbtExperimentation PlatformsPythonSnowflakeSQL
Reposted 7 Days AgoSaved
Remote
Colorado
160K-220K Annually
Senior level
160K-220K Annually
Senior level
Fintech • Financial Services
Lead and deliver end-to-end data science projects: design, build, deploy, and monitor ML/statistical models for credit risk, pricing, collections, and fraud. Partner with cross-functional teams to integrate models into production, set model development standards, mentor engineers, and maintain reliable ML pipelines and monitoring systems.
Top Skills: AWSGitPythonSagemakerSQL
Reposted 4 Days AgoSaved
Remote
Colorado
Senior level
Senior level
Machine Learning • Software
The Staff Data Scientist will lead the development and deployment of ML and GenAI systems to detect billing errors and fraud in healthcare payments, collaborating with cross-functional teams.
Top Skills: AIData ScienceMachine Learning
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Reposted 6 Days AgoSaved
Remote
Colorado
Senior level
Senior level
Cloud • Information Technology • Software • Consulting • Web3
Seeking a skilled Data Scientist/Machine Learning Engineer to develop machine learning models, design AI systems, and collaborate in data analytics. Responsibilities include productionizing models, data engineering, and cross-functional collaboration.
Top Skills: AirflowAWSAzureCi/CdDockerGCPJIRAKubeflowKubernetesMlflowNumpyPandasPlantumlPythonPyTorchSparkTfx
Reposted 7 Days AgoSaved
Remote
Colorado
175K-234K Annually
Senior level
175K-234K Annually
Senior level
Information Technology • Other • Social Media
As a Senior Data Scientist, you'll optimize search relevance, retrieve content, analyze data, and collaborate with teams to enhance product strategies.
Top Skills: Ml ModelsNumpyPandasPythonScikit-LearnSQL
Reposted 9 Days AgoSaved
Remote
Colorado
217K-289K Annually
Senior level
217K-289K Annually
Senior level
Internet of Things
Lead data-driven strategy by partnering with senior executives to deliver rigorous analytical solutions. Design and implement sophisticated analyses on large-scale data, build trusted cross-functional relationships, mentor data scientists, and influence long-term product and business decisions.
Top Skills: PythonRSQL
Reposted 15 Days AgoSaved
Remote
Colorado
180K-230K Annually
Senior level
180K-230K Annually
Senior level
Fintech • Information Technology • Software
As a Senior Data Scientist, you'll develop fraud detection models, perform detailed analyses, and work closely with teams to drive product innovation and business outcomes.
Top Skills: Aws Ec2Aws RdsAws RedshiftAws S3PostgresPython 3
Reposted 15 Days AgoSaved
Easy Apply
Remote
Colorado
Easy Apply
160K-200K Annually
Senior level
160K-200K Annually
Senior level
Artificial Intelligence • Enterprise Web • Information Technology • Productivity • Sales • Software • Database
The Senior Data Scientist will analyze data to drive product strategy, optimize performance, and support product launches, collaborating with cross-functional teams.
Top Skills: A/B TestingAmplitudeHeapLookerMachine LearningMixpanelPythonRSASSQL
Reposted 11 Days AgoSaved
Remote
Colorado
24K-185K Annually
Senior level
24K-185K Annually
Senior level
Cloud • Marketing Tech • Sales • Software
Design, build, and deploy predictive GTM models (LTV, attribution, propensity). Lead experimentation and causal analyses, define KPI measurement frameworks, partner with Data Engineering, and translate statistical insights into actionable recommendations for Sales, Marketing, and Customer Success.
Top Skills: AirflowDatabricksDbtNumpyPandasPythonRScikit-LearnSnowflakeSQL
Reposted 11 Days AgoSaved
Remote
Colorado
130K-168K Annually
Senior level
130K-168K Annually
Senior level
Aerospace • Information Technology • Professional Services • Security • Software
Lead a 5–8 person Data Science team to develop and operationalize FWA detection models using SAS and Python on multi‑payer healthcare claims. Oversee model development, data pipelines, quality reviews, stakeholder presentations, and collaboration with SMEs and BI developers. Split role ~40% management, 60% hands-on coding/analysis.
Top Skills: AWSCptDrgHcpcsIcd-10ExcelMicrosoft PowerpointMicrosoft WordPythonSASSnowflakeSQL
Reposted 13 Days AgoSaved
Remote
Colorado
Senior level
Senior level
Machine Learning • Software
As a Staff Data Scientist, you will lead initiatives to build and optimize machine learning models, collaborate across departments, and solve complex business problems using data.
Top Skills: LlmMlSQL
Reposted 13 Days AgoSaved
Remote
Colorado
140K-240K Annually
Senior level
140K-240K Annually
Senior level
Greentech
As a Data Scientist, you will build predictive models, develop software tools, and analyze geoscientific data to support mineral exploration and discovery.
Top Skills: Cicd PipelinesCloud ComputingCollaborative Software DevelopmentData Science PackagesGeospatial AnalysesGitMachine LearningPythonVisualizations
Reposted 13 Days AgoSaved
Remote
Colorado
140K-240K Annually
Senior level
140K-240K Annually
Senior level
Greentech
As a Data Scientist, you will develop predictive models, analyze geoscientific data, and collaborate with geoscientists to improve mineral exploration efforts.
Top Skills: Cloud ComputingGeospatial AnalysisPythonSoftware Engineering
16 Days AgoSaved
In-Office or Remote
Colorado
109K-181K Annually
Senior level
109K-181K Annually
Senior level
Healthtech • Information Technology • Software
Provide analytics and data-driven insights for CoverMyMeds clients, prioritize work that drives commercial outcomes, build relationships with account teams, apply statistical and predictive methods, monitor portfolio health, deliver client-facing visuals and recommendations, support complex requests and escalations, and inform strategic decisions across product, analytics, and operations.
Top Skills: ExcelMatlabPythonRSASSQLTableau
Reposted 16 Days AgoSaved
Remote
Colorado
200K-242K Annually
Senior level
200K-242K Annually
Senior level
Real Estate • Travel • PropTech
Develop frameworks and tooling to estimate long-term impacts of product changes from short-term experiment outcomes. Build causal inference methods (experimental, econometric, quasi-experimental), evaluate heterogeneous treatment effects, own major estimation problems, and communicate results to technical and non-technical stakeholders to drive better long-term decisions.
Top Skills: C++JavaPythonRScala
17 Days AgoSaved
In-Office
Colorado
150K-175K Annually
Senior level
150K-175K Annually
Senior level
Aerospace
Support USASMDC by researching and analyzing structured and unstructured data, building complex database queries, integrating diverse data sources, extracting actionable insights, and communicating findings to government stakeholders within large-scale enterprise data environments.
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