Top Senior Data Science Jobs in Denver & Boulder, CO

Lead the development of statistical and machine learning models for time-series and geospatial data. Build analytic solutions, datasets, ETL workflows, forecasting and anomaly-detection models, simulations, visualizations, and reports. Evaluate algorithm performance, optimize classifiers, document processes, and collaborate with engineers, analysts, mission partners, and stakeholders to deliver reliable mission-focused software and data capabilities.

Lead statistical and machine learning model development for time-series and geospatial data supporting the FALCON mission. Responsibilities include feature engineering, forecasting, anomaly detection, ETL, dataset creation, algorithm evaluation, simulation, data visualization, reporting, documentation, and stakeholder collaboration. The role also contributes to software applications, APIs, data pipelines, code reviews, troubleshooting, and iterative agile development.

Leads teams in designing and deploying scalable AI and machine learning solutions for consulting clients. Responsibilities include data wrangling, complex analysis, data modeling, AI system implementation, data pipeline and infrastructure oversight, deep learning, neural networks, data quality validation, and stakeholder collaboration. The manager coaches team members, manages performance, supports innovation, and applies Python, Java, and cloud technologies to build production-ready AI applications.

Build predictive failure models, real-time anomaly detection systems, diagnostic tools, and operational dashboards for spacecraft manufacturing, testing, and integration. Apply statistical modeling, causal inference, reliability analysis, and data mining to identify root causes, bottlenecks, quality issues, supplier risks, and process improvements. Develop reproducible Python and SQL analyses that support engineering decisions and mission reliability.

Build predictive models, anomaly detection systems, diagnostic tools, dashboards, and statistical quality-monitoring solutions for spacecraft manufacturing and testing. Analyze telemetry, production, supplier, and reliability data to identify failures, bottlenecks, delays, and root causes. Develop reproducible Python and SQL analyses and communicate actionable findings to engineering and operations stakeholders.

Set the technical vision for data science, lead complex statistical and machine learning model development from concept through production, and architect scalable modeling platforms and pipelines. Develop credit risk, pricing, and loss forecasting models; establish model governance standards; partner with senior leaders; mentor data scientists; and communicate technical strategy to executives. The role emphasizes production deployment, monitoring, cloud architecture, and high-impact decision-making across the business.

Own product analytics for a healthcare platform by translating business questions into research plans, uncovering insights, modeling feature impacts, defining success criteria, and leading A/B testing. Partner with Product, Data Engineering, Finance, Clinical, and Operations teams to influence roadmap decisions, improve provider experience and quality, and optimize marketplace performance.

Partner with clients to design healthcare data science solutions, curate multimodal clinical datasets, and conduct statistical, predictive, causal inference, real-world evidence, and AI/ML analyses. Responsibilities include querying EMR and other health data sources, creating statistical analysis plans, managing SQL and analytical programming, ensuring HIPAA-compliant data quality, documenting findings, and presenting results to technical, clinical, and executive audiences.

Develop foundation models for longitudinal wearable and physiological data, leading research from hypothesis development through modeling, experimentation, evaluation, prototyping, and product deployment. Build datasets and ML infrastructure, advance representation learning, forecasting, personalization, multimodal and generative modeling, and establish robust evaluation methods. Collaborate with scientists, clinicians, engineers, and product teams while translating research into health experiences.

Lead development of statistical and machine learning models for time-series, geospatial, kinematic, and radar data. Build analytic solutions, training datasets, ETL workflows, forecasting and anomaly-detection models, simulations, visualizations, and performance metrics. Integrate multi-source sensor data, enhance algorithms, document processes, and collaborate with engineers, analysts, mission partners, and stakeholders in an agile environment.

Develops statistical and machine learning models, analyzes complex datasets, builds trustworthy data assets, and generates insights that support business growth and customer behavior analysis. The role collaborates with stakeholders, data engineers, and architects; leads high-impact projects; informs experimental design; optimizes model performance; and mentors colleagues in data science and machine learning.

Design and analyze rigorous messaging experiments using A/B testing and causal inference. Build measurement frameworks, data pipelines, dashboards, automated analyses, and scalable data solutions for messaging campaigns. Partner with CRM, Product, Algorithms, and Engineering teams to translate ambiguous business questions into actionable recommendations and experimentation standards. Support messaging strategy across channels, timing, content, targeting, and new business verticals.

Develop and productionize machine learning models and predictive analytics using Python, Databricks, PySpark, SQL, and Delta Lake. Build scalable data science workflows, resolve healthcare data quality and entity-resolution issues, and apply Master Data Management practices. Partner with engineering, product, analytics, and business teams to deliver governed, HIPAA-compliant solutions. Perform exploratory analysis, feature engineering, model evaluation, deployment, documentation, and data lineage management for healthcare and member engagement initiatives.

Consult as a fractional data scientist for hedge funds, private equity firms, and family offices. Lead data science initiatives: build infrastructure, develop and deploy models, create portfolio dashboards, monitor post-deployment performance, and partner with investment teams to turn data into actionable investment insights. Advise on vendor selection, data quality, technology stacks, KPIs, and governance.

Develop marketing analytics and data science models to measure campaign effectiveness, ROI, attribution, customer lifetime value, and marketing impact. Apply causal inference, experimentation, and Marketing Mix Modeling; automate model pipelines and monitoring; build insight-ready datasets and self-service dashboards; and communicate actionable findings to marketing and executive stakeholders. The role also supports campaign analysis, data requirements, training, and strategic planning.

Lead end-to-end pricing experimentation and strategy for consumer and business products. Design and analyze A/B tests, build pricing models and production-grade data pipelines, partner cross-functionally, and present actionable recommendations to senior leadership.

Develop and sustain mission-critical data products for U.S. government and defense customers. Build data pipelines, analytical workflows, structured data models, dashboards, and user-facing applications using Python, SQL, and Palantir Foundry. Collaborate with technical and operational stakeholders throughout requirements, development, testing, deployment, onboarding, and sustainment. The role requires active Secret clearance, U.S. citizenship, and the ability to obtain TS/SCI clearance.

Leads applied AI/ML research as Principal Investigator and technical leader. Defines research portfolios, experiments, evaluation plans, and transition criteria; remains hands-on with prototypes, models, code, and end-to-end AI architectures. Leads cross-functional teams, mentors technical staff, evaluates emerging technologies, and transitions successful research into secure, scalable production capabilities using software engineering and MLOps practices. Communicates technical strategies to customers, business leaders, and engineering teams.

Design and deploy optimization and machine learning models for allocating scarce parts and resources across competing programs. Responsibilities include formulating MILP and constraint optimization models, forecasting demand and supply risk, building data pipelines, validating outputs, communicating tradeoffs to stakeholders, mentoring junior data scientists, and partnering with software engineers to productionize scalable services.

Lead performance marketing data science initiatives focused on lead segmentation, bidding optimization, targeting, and marketing spend allocation. Develop and deploy production-ready machine learning systems, establish research and ML operations roadmaps, build monitoring frameworks, and identify high-impact opportunities. Partner with engineering, marketing, vendors, and executives while mentoring data scientists and machine learning engineers and promoting rigorous, maintainable, and reproducible practices.

Lead data science for Mozilla’s advertising business by identifying high-impact opportunities, owning complex analyses, developing measurement and experimentation frameworks, analyzing revenue and performance, and translating findings into recommendations for technical partners and executives. Partner across Product, Engineering, Sales, Finance, and leadership to support business decisions in a fast-moving environment while balancing analytical rigor, pragmatism, and user privacy.

Lead data science partnership for Mozilla’s advertising business, identifying high-impact opportunities and owning complex analytics end to end. Develop measurement frameworks, experimentation strategies, instrumentation, and reporting for advertising products. Analyze revenue and performance, evaluate trade-offs, and communicate clear recommendations and uncertainty to technical teams and senior executives.

Build and implement data science models, algorithms, simulations, and analytics solutions for Army mission data. Responsibilities include mathematical modeling, large-scale data processing, software algorithm development, machine learning deployment optimization, MLOps framework support, tool integration, and application enhancement for defense customers.

Staff Data Scientist responsible for owning ambiguous, high-impact product and business problems; designing experiments; analyzing product data; developing analytical tools and frameworks; partnering with product, engineering, design, and leadership; and mentoring data scientists. The role requires advanced statistical expertise, strong product judgment, production programming experience, and the ability to translate complex analyses into strategic recommendations.

Conduct workforce analytics and applied organizational research on attrition, mobility, engagement, performance, and planning. Analyze and validate HR data using SQL, R, or Python; apply statistical testing and regression; translate business questions into actionable insights; and communicate findings through visualizations, reports, and presentations. Partner with HR stakeholders while maintaining the accuracy, documentation, confidentiality, and integrity of sensitive workforce data.