Top Senior Data Science Jobs in Denver & Boulder, CO

Reposted 17 Hours AgoSaved
Hybrid
Colorado
99K-232K Annually
Senior level
99K-232K Annually
Senior level
Artificial Intelligence • Professional Services • Business Intelligence • Consulting • Cybersecurity • Generative AI
Lead teams applying advanced data science and machine learning to large-scale claims, clinical, and member data to generate actionable insights that reduce cost of care and improve population health. Manage client relationships, mentor staff, ensure project delivery and quality, develop payer-focused analytics products, present findings to senior stakeholders, and promote continuous improvement and knowledge sharing.
Top Skills: Claims DataClinical DataCms Star RatingsMachine LearningNcqa HedisNlpSocial Determinants Of Health (Sdoh) Data
Reposted 2 Days AgoSaved
Easy Apply
Remote
Colorado
Easy Apply
207K-244K Annually
Senior level
207K-244K Annually
Senior level
Artificial Intelligence • Blockchain • Fintech • Financial Services • Cryptocurrency • NFT • Web3
Lead end-to-end pricing experimentation and strategy for consumer and business products. Design and analyze A/B tests, build pricing models and production-grade data pipelines, partner cross-functionally, and present actionable recommendations to senior leadership.
Top Skills: Generative AiPythonRSQL
3 Days AgoSaved
Remote
Colorado
166K-193K Annually
Senior level
166K-193K Annually
Senior level
Healthtech • Social Impact • Software • Telehealth
Analyze billing patterns, healthcare claims, and complex datasets to identify anomalies, audit data integrity, and support Trust and Safety initiatives. Build risk-monitoring pipelines and compliance dashboards using SQL, Python/R, and visualization tools. Translate technical findings into risk assessments for legal, compliance, and executive partners while developing safeguards to protect patients, regulatory standing, and platform operations.
Top Skills: HexLookerModePythonRSQLTableau
10 Days AgoSaved
Easy Apply
Remote
Colorado
Easy Apply
153K-180K Annually
Senior level
153K-180K Annually
Senior level
Artificial Intelligence • Fintech • Healthtech • Software
Lead product analytics efforts by designing and evaluating experiments, building dashboards, and producing statistical insights. Partner with product, design, and engineering to measure product success, identify optimization opportunities, and embed ML-driven personalization into the product.
Top Skills: DbtHexLookerPythonSQL
Reposted 16 Days AgoSaved
Easy Apply
Remote
Colorado
Easy Apply
236K-295K Annually
Senior level
236K-295K Annually
Senior level
Artificial Intelligence • Enterprise Web • Information Technology • Productivity • Sales • Software • Database
Lead product analytics to inform strategy and optimize user experience: translate business questions into analysis, build reliable analytics infrastructure, run A/B tests and ML/statistical analyses, track funnels and cohorts, support 0-to-1 product launches, and communicate actionable insights to cross-functional teams.
Top Skills: A/B TestingAmplitudeHeapLookerMachine LearningMixpanelPythonRSASSQLStatistical Analysis
18 Days AgoSaved
Hybrid
Colorado
Senior level
Senior level
eCommerce • Mobile • Payments
Lead data science initiatives across core business domains: collaborate with stakeholders and engineers, analyze large datasets, design experiments, build and productionize statistical and ML models, harden pipelines, monitor performance, and mentor teams to drive data-informed decisions.
Top Skills: Graph Data SchemasMlopsPysparkPythonRSparkSQL
Reposted YesterdaySaved
Remote
Colorado
160K-220K Annually
Senior level
160K-220K Annually
Senior level
Fintech • Financial Services
Lead and deliver end-to-end data science projects: design, build, deploy, and monitor ML/statistical models for credit risk, pricing, collections, and fraud. Partner with cross-functional teams to integrate models into production, set model development standards, mentor engineers, and maintain reliable ML pipelines and monitoring systems.
Top Skills: AWSGitPythonSagemakerSQL
2 Days AgoSaved
Remote
Colorado
165K-220K Annually
Senior level
165K-220K Annually
Senior level
Artificial Intelligence • Machine Learning • Natural Language Processing • Software • Conversational AI
Analyze and characterize conversational audio data, identify underrepresented areas, and build active-learning and human-in-the-loop workflows. Develop representative benchmarks, automate model adaptation, and create reusable data analysis and scoring systems. Partner with research, engineering, and data teams to run experiments, improve models, organize data, and translate complex findings into measurable product improvements.
Top Skills: Active LearningAsrData PipelinesEnsemble LabelingGdprLlmsMachine LearningNlpPseudo-LabelingPythonTts
Reposted 15 Hours AgoSaved
Remote
Colorado
200K-242K Annually
Senior level
200K-242K Annually
Senior level
Real Estate • Travel • PropTech
Develop frameworks and tooling to estimate long-term impacts of product changes from short-term experiment outcomes. Build causal inference methods (experimental, econometric, quasi-experimental), evaluate heterogeneous treatment effects, own major estimation problems, and communicate results to technical and non-technical stakeholders to drive better long-term decisions.
Top Skills: C++JavaPythonRScala
Reposted 16 Hours AgoSaved
Remote
Colorado
Senior level
Senior level
AdTech • Big Data • Consumer Web • Digital Media • Marketing Tech
Lead end-to-end data science for a priority vertical (Insurance), building, validating, and deploying ML models that drive ROAS and lead quality. Partner with stakeholders and ML engineering to monitor live performance, iterate models, and identify new modeling opportunities to improve revenue and media efficiency.
Top Skills: AWSLtv ModelingMulti-Armed BanditPythonRanking SystemsRecommendation SystemsReinforcement LearningSQL
Reposted 17 Hours AgoSaved
In-Office
Colorado
150K-175K Annually
Senior level
150K-175K Annually
Senior level
Aerospace
Support USASMDC by researching and analyzing structured and unstructured data, building complex database queries, integrating diverse data sources, extracting actionable insights, and communicating findings to government stakeholders within large-scale enterprise data environments.
YesterdaySaved
Remote
Colorado
175K-250K Annually
Senior level
175K-250K Annually
Senior level
Artificial Intelligence • Fintech • Software • Financial Services
Develop and optimize machine learning and statistical models for fraud detection and anti-money laundering. Analyze large datasets to identify fraudulent patterns, build scalable data pipelines and features, evaluate model performance, and collaborate with engineering, product, and operations teams. Communicate insights to technical and non-technical stakeholders while maintaining data privacy and security compliance. The role offers significant ownership in building Oscilar’s early machine learning stack within a remote-first startup.
Top Skills: SparkAWSAzureDaskGCPMachine LearningMlopsPythonStatistical Modeling
New

Cut your apply time in half.

Use ourAI Assistantto automatically fill your job applications.

Use For Free
Application Tracker Preview
YesterdaySaved
Remote
Colorado
130K-163K Annually
Senior level
130K-163K Annually
Senior level
Financial Services
Oversee development, validation, monitoring, and governance of consumer credit risk models used for loss forecasting, credit decisioning, regulatory reporting, and risk management. Apply statistical, econometric, and machine learning methods to PD, LGD, and EAD models; support CECL, stress testing, and macroeconomic scenario analysis. Assess model performance, data quality, and compliance while communicating findings to senior leaders, auditors, regulators, and other stakeholders.
Top Skills: Basel IiiCcarCeclDfastDodd-FrankEconometric ModelingIfrs 9Machine LearningPythonRSASSQLStatistical Modeling
2 Days AgoSaved
In-Office
Colorado
112K-196K Annually
Senior level
112K-196K Annually
Senior level
Information Technology • Security • Cybersecurity
Develops end-to-end data science and analytics solutions for DoD mission environments. Responsibilities include ingesting and transforming structured and unstructured data, creating ETL pipelines, querying SQL databases, performing statistical and predictive analysis, building Power BI dashboards, integrating APIs and enterprise systems, improving data quality, automating workflows, and communicating insights to stakeholders. The role also supports data architecture, testing, documentation, and compliance with cybersecurity and DoD data-handling requirements.
Top Skills: APIsAWSC#DomoETLExcelLinuxMicrosoft Power PlatformMicrosoft Sql ServerPower AppsPower AutomatePower BIPythonRSharepointSQLSsdtSsmsSsrsTableauVBA
Reposted 2 Days AgoSaved
Remote
Colorado
150K-160K Annually
Senior level
150K-160K Annually
Senior level
Insurance • Pet
Develop and maintain predictive pricing, retention, and conversion models using GLMs and advanced analytics; build monitoring tools for rating performance; support rate filings, product pricing analyses, competitor research, and cross-functional collaboration to inform pricing and enterprise risk decisions.
Top Skills: ClaudeElastic NetExcelGeminiGeneralized Linear Models (Glms)Geospatial StatisticsGithub CopilotK-Means ClusteringPythonRSerffSQL
3 Days AgoSaved
In-Office
Colorado
140K-150K Annually
Senior level
140K-150K Annually
Senior level
Aerospace
Develop mathematical, statistical, and machine learning models to solve complex problems across multiple domains. Analyze datasets, automate tasks, communicate analytical results, and align solutions with customer and management objectives. The role supports defense and space-related programs, requires collaboration with government and contractor teams, and is performed onsite in Colorado Springs.
Top Skills: ContainerizationDatabasesEnvisionJmpKerasNumpyPandasPlotly DashPsppPythonPyTorchSASScikit-LearnSpssSympyTensorFlowWarp Core
3 Days AgoSaved
Remote
Colorado
123K-205K Annually
Senior level
123K-205K Annually
Senior level
Energy • Manufacturing • Solar • Renewable Energy
Design and build thermal performance analytics, Python-based engineering models, scalable data flows, and Edge-native applications for power plant asset performance management. Integrate historian, cloud, Edge, and industrial systems; develop automation, diagnostics, KPI validation, and root-cause workflows; support customer deployments; and lead architecture discussions while mentoring engineering teams.
Top Skills: Ai/MlCi/CdCloud ComputingContainerizationDigital TwinsDockerEdge ComputingGenerative AiGitIndustrial IotLinuxMicroservicesMqttOpc-UaPlant Historian SystemsPythonRest ApisTespyTime-Series Data Processing
3 Days AgoSaved
In-Office
Colorado
78K-176K Annually
Senior level
78K-176K Annually
Senior level
Information Technology
Develop predictive models, algorithms, quantitative analyses, and data visualizations from structured and unstructured data. Explore, clean, analyze, and interpret complex datasets using statistical programming, machine learning, NLP, and text-mining techniques. Collaborate with clients to identify data-driven solutions, lead solution development for complex programs, guide teammates, and provide insights supporting informed decisions.
Top Skills: Amazon EmrArtificial IntelligenceGgplot2GurobiHadoopHiveInternet Of Things (Iot)KafkaMachine LearningMapreduceMySQLNatural Language Processing (Nlp)NoSQLPlotlyPythonRSeabornSparkSQLText Mining
Reposted 3 Days AgoSaved
Remote
Colorado
100K-720K Annually
Senior level
100K-720K Annually
Senior level
News + Entertainment
Lead research and experimentation to measure ad campaign performance and effectiveness. Design evaluation frameworks, build measurement solutions, develop models for lift, conversion, and attribution, run experiments and analyses, partner with product/engineering/design/sales, present insights, mentor teammates, and foster technical community and culture.
Top Skills: A/B TestingMachine LearningPythonRSQL
Reposted 3 Days AgoSaved
Remote
Colorado
212K-318K Annually
Senior level
212K-318K Annually
Senior level
Gaming
Lead design, execution, and interpretation of A/B tests and quasi-experiments; apply causal inference methods; partner with product, engineering, and marketing; mentor data scientists; build experimentation frameworks; extract and analyze data using SQL and Python; communicate results to stakeholders.
Top Skills: A/B TestingCausal InferenceExperimentation FrameworksMachine LearningPythonQuasi-Experimental MethodsSQL
Reposted 5 Days AgoSaved
Remote
Colorado
Senior level
Senior level
Cloud • Software
Design and deploy predictive forecasting and analytics to support Revenue operations. Build models for forecasting, churn, expansion, and pipeline analytics; create scalable dashboards; partner with Revenue Operations, Finance, and Data Engineering to improve data quality, KPI governance, and executive reporting to drive data-driven decisions and AI readiness.
Top Skills: DashboardsData VisualizationForecastingPredictive AnalyticsPythonSQLStatistical Modeling
Reposted 5 Days AgoSaved
Remote
Colorado
Senior level
Senior level
Healthtech
Own end-to-end modeling for vendor matching, order routing, and supply-chain optimization. Build predictive, causal, RL and OR solutions; design autonomous decision logic; quantify counterfactual impact; ship production models with data engineering; mentor senior data scientists; write technical design docs; partner on quarterly priorities and expand into revenue cycle and finance domains.
Top Skills: Agentic AiCausal InferenceCausal MlDiscrete Event SimulationForecastingGitMachine LearningOperations ResearchPythonQueueing TheoryReinforcement LearningSQL
Reposted 6 Days AgoSaved
Remote
Colorado
145K-180K Annually
Senior level
145K-180K Annually
Senior level
Healthtech • Telehealth
Senior individual contributor who drives product analytics, experimentation, and applied modeling. Owns growth and performance analyses, designs experiments with robust statistical evaluation, builds repeatable reporting, and partners with Product, Engineering, Operations, Clinical, and Finance to translate data into actionable product and operational decisions.
Top Skills: BigQueryPandasPythonRedshiftScikit-LearnSnowflakeSQLStatsmodels
12 Days AgoSaved
Remote
Colorado
192K-228K Annually
Senior level
192K-228K Annually
Senior level
Healthtech • Social Impact • Software • Telehealth
Owner of analytics for EHR, revenue cycle, and operations: design and run experiments, analyze financial and operational metrics, investigate billing and account issues, and deliver actionable insights to Product, Operations, Finance, and Customer Experience to improve accuracy, reduce friction, and support growth.
Top Skills: EhrHexLookerPythonRevenue Cycle ManagementSQLTableau
7 Days AgoSaved
In-Office
Colorado
99K-225K Annually
Senior level
99K-225K Annually
Senior level
Information Technology
Lead client-facing data science efforts to develop AI/ML solutions (including LLMs/agentic AI), guide teammates, clean and model complex data, evaluate model accuracy, visualize results for leadership, and work on classified networks requiring TS/SCI clearance.
Top Skills: Agentic AiEmrGgplot2GurobiHadoopHiveIotKafkaLlmsMapreduceMySQLNoSQLPlotlyPythonRSeabornSparkSQL
All Filters
JobType
New Jobs
Job Category
Experience
Industry
Company Name
Company Size

Sign up now Access later

Create Free Account