Top Senior Data Science Jobs in Denver & Boulder, CO

Lead data science initiatives across core business domains: collaborate with stakeholders and engineers, analyze large datasets, design experiments, build and productionize statistical and ML models, harden pipelines, monitor performance, and mentor teams to drive data-informed decisions.

Lead research projects that develop and improve data science methodologies and algorithms. Analyze existing solutions, build and test data extraction and transformation architectures, and collaborate with Technology and Product Management on deployment. Investigate production and client data issues, provide data analysis support, maintain SQL, Python, and R code, document processes, and present research findings to internal clients.

As a Staff Data Scientist, you will analyze large-scale broadband data, develop and validate ML models, and integrate solutions into Calix Cloud, collaborating with teams for enhanced network intelligence and subscriber experience.

Leads applied AI/ML research as Principal Investigator and technical leader, defining research portfolios, experiments, evaluation plans, and transition criteria. Builds prototypes and end-to-end AI systems, guides cross-functional teams, mentors technical staff, and transitions successful solutions into secure, production-grade capabilities. Communicates with customers and business leaders while assessing emerging AI technologies and developing reusable architectures and practices.

The Senior Data Scientist will analyze data to drive product strategy, optimize performance, and support product launches, collaborating with cross-functional teams.

As a Senior Data Scientist, you'll develop fraud detection models, perform detailed analyses, and work closely with teams to drive product innovation and business outcomes.

Supports U.S. Army intelligence missions by integrating and analyzing structured and unstructured data. Develops database queries, algorithms, models, automated processes, data strategies, visualization, and analytical tools using machine learning, NLP, computer vision, and statistical techniques. Curates intelligence data, integrates SIGINT, GEOINT, all-source, and targeting datasets, and communicates insights to technical and non-technical stakeholders. Requires active TS/SCI clearance and supports a one-year customer-funded effort.

Lead the strategic direction and evolution of Netflix’s company-wide Experimentation Platform. Establish rigorous causal inference and experimentation standards, automate trust and validation practices, consolidate fragmented systems, shape platform product roadmaps, and collaborate with data science and engineering leaders. Translate experimentation needs into scalable tools, influence adoption across teams, mentor colleagues, and ensure reliable experiment allocation, measurement, analysis, and reporting.

Lead and deliver end-to-end data science projects: design, build, deploy, and monitor ML/statistical models for credit risk, pricing, collections, and fraud. Partner with cross-functional teams to integrate models into production, set model development standards, mentor engineers, and maintain reliable ML pipelines and monitoring systems.

Analyze and characterize conversational audio data, identify underrepresented areas, and build active-learning and human-in-the-loop workflows. Develop representative benchmarks, automate model adaptation, and create reusable data analysis and scoring systems. Partner with research, engineering, and data teams to run experiments, improve models, organize data, and translate complex findings into measurable product improvements.

Leads graph analytics, identity resolution, forecasting, and predictive modeling initiatives for operational, commercial, and product decisions. Designs scalable graph data models, production-ready machine learning solutions, and time-series forecasts. Establishes validation, monitoring, governance, and experimentation practices while partnering with product, engineering, and platform teams. Translates complex analytical findings into business recommendations and provides technical leadership across graph science, forecasting, optimization, and decision-support capabilities.

Build and deploy production-grade LLM applications, AI agents, models, and scalable RAG pipelines for investment and business workflows. Architect secure MCP integrations with enterprise systems, establish MLOps and LLMOps practices, optimize model performance and latency, and develop evaluation, monitoring, governance, and rollback processes. Collaborate with data engineering and platform teams to provide secure, governed access to organizational data.

Provide analytics and data-driven insights for CoverMyMeds clients, prioritize work that drives commercial outcomes, build relationships with account teams, apply statistical and predictive methods, monitor portfolio health, deliver client-facing visuals and recommendations, support complex requests and escalations, and inform strategic decisions across product, analytics, and operations.

Lead end-to-end data science for a priority vertical (Insurance), building, validating, and deploying ML models that drive ROAS and lead quality. Partner with stakeholders and ML engineering to monitor live performance, iterate models, and identify new modeling opportunities to improve revenue and media efficiency.

Oversee development, validation, monitoring, and governance of consumer credit risk models used for loss forecasting, credit decisioning, regulatory reporting, and risk management. Apply statistical, econometric, and machine learning methods to PD, LGD, and EAD models; support CECL, stress testing, and macroeconomic scenario analysis. Assess model performance, data quality, and compliance while communicating findings to senior leaders, auditors, regulators, and other stakeholders.

Designs AI risk stratification and evaluation methodologies for Veterans Health Administration systems, assessing performance, fairness, value, and post-deployment monitoring. Provides technical guidance on machine learning, healthcare data models, cohorts, synthetic data, and pilot evaluations. Develops risk management materials and supports governance decisions through quantitative analysis. Requires extensive applied data science experience, advanced education, and expertise in healthcare-focused machine learning.

Lead statistical modeling, AI/ML evaluation, data governance, data quality assurance, and executive analytics for VA EHR modernization. Build reproducible R-based analytics, reporting pipelines, dashboards, and governed data products using R, SQL, Python, Git, and cloud platforms. Evaluate model reliability, bias, drift, and operational value; integrate complex healthcare data; define metrics and validation rules; and advise stakeholders on auditable analytical practices.

Develop mathematical, statistical, and machine learning models to solve complex problems across multiple domains. Analyze datasets, automate tasks, communicate analytical results, and align solutions with customer and management objectives. The role supports defense and space-related programs, requires collaboration with government and contractor teams, and is performed onsite in Colorado Springs.

Develop predictive models, algorithms, quantitative analyses, and data visualizations from structured and unstructured data. Explore, clean, analyze, and interpret complex datasets using statistical programming, machine learning, NLP, and text-mining techniques. Collaborate with clients to identify data-driven solutions, lead solution development for complex programs, guide teammates, and provide insights supporting informed decisions.

Lead research and experimentation to measure ad campaign performance and effectiveness. Design evaluation frameworks, build measurement solutions, develop models for lift, conversion, and attribution, run experiments and analyses, partner with product/engineering/design/sales, present insights, mentor teammates, and foster technical community and culture.

Lead design, execution, and interpretation of A/B tests and quasi-experiments; apply causal inference methods; partner with product, engineering, and marketing; mentor data scientists; build experimentation frameworks; extract and analyze data using SQL and Python; communicate results to stakeholders.

Build and deploy predictive models that drive partner action, analyze conversational and unstructured data using NLP techniques, and monitor model performance in production. Own AI data tooling, evaluation frameworks, in-warehouse model configuration, and reusable analytics foundations. The role also establishes modeling standards, evaluates fairness and limitations, collaborates with engineering and product teams, and prioritizes high-impact work across a lean data organization.

Leads enterprise manufacturing AI, machine learning, and Industry 4.0 initiatives across multiple plants. Develops and deploys solutions for predictive maintenance, process and quality optimization, energy efficiency, throughput, and OEE improvement. Establishes scalable data and AI platforms, governance, and MLOps standards while integrating industrial data sources. Leads and mentors data science teams, prioritizes projects, allocates resources, partners with cross-functional manufacturing stakeholders, and presents strategic recommendations and business cases to executives.

Senior Data Scientist partnering with Product, Engineering, and Design teams to analyze user behavior, product performance, and marketplace dynamics. Responsibilities include developing metrics and reporting frameworks, designing experiments, diagnosing business trends, analyzing marketplace behavior, and aligning stakeholders on analytical priorities. The role uses SQL and Python alongside BigQuery, dbt Cloud, Airflow, Tableau, and Statsig, with a focus on product analytics, experimentation, and data-informed decision-making.

Lead ecosystem-level data science and econometric analyses across Xbox, Game Pass, Console, PC, and Store experiences. Evaluate growth, engagement, monetization, experiments, incrementality, and investment ROI using statistical and causal inference methods. Build reusable analytical products and self-service capabilities, influence executive decisions, and mentor team members.