Top Senior Data Science Jobs in Denver & Boulder, CO

Lead end-to-end data science for customer-embedded, production solutions: acquire and prepare messy datasets, develop and evaluate models tied to business outcomes, run experiments, deploy operational models at scale, coach cross-disciplinary teams, and drive strategy, ethics, and privacy discussions.

Lead end-to-end data science projects: acquire and prepare messy datasets, develop and evaluate models tied to business outcomes, operationalize models at scale, run experiments, drive ethics/privacy, partner with customers and teams, and coach cross-disciplinary colleagues.

Build reliability and quality models for consumer hardware, analyze manufacturing and telemetry data, develop predictive and decision-support systems, and translate findings into product, quality, firmware, warranty, and supply-chain decisions. The role combines statistical modeling, machine learning, experimentation, data engineering, and cross-functional technical leadership.

Leads product analytics strategy across Xbox experiences, establishing metrics, experimentation, causal inference, forecasting, and machine-learning approaches to guide investments and improve growth outcomes. Partners with senior Product, Engineering, and Business leaders, builds scalable measurement frameworks and AI-enabled analytical capabilities, strengthens telemetry and data quality, and mentors data scientists while setting methodological standards.

The Senior Data Scientist designs and deploys LLM-powered agents connecting with building energy modeling and HVAC simulation tools. Responsibilities include creating agentic workflows, ETL pipelines, data preprocessing, machine learning modeling, validation tools, reports, visualizations, and documentation. The role collaborates across teams, reviews work, communicates with clients, and supports rapid application deployment. Travel is required 10–20% of the time.

Own analytical relationships with travel technology partners, creating scalable reporting on supply, pricing, and performance. Conduct exploratory analysis, apply machine learning and statistical methods, build dashboards, automate recurring workflows with AI tools, and translate complex findings into recommendations for product, engineering, commercial, and executive audiences.

Leads data science research from question framing through modeling, validation, and recommendations. Partners with executives, business leaders, ML engineers, and data engineers to identify opportunities in risk, fraud, retention, pricing, and compliance. Builds forecasts and production-ready models, evaluates data as a strategic asset, and translates insights into product features, offerings, and measurable business outcomes.

Unpaid remote internship focused on data extraction, scraping, mining, processing, cleaning, pipeline development, AI model training, and containerized microservices. The intern will use Django, Puppeteer, Selenium, Docker, Pandas, NumPy, Scikit-learn, Git, and GitHub while applying testing and data engineering practices. The role requires at least 30 hours weekly and may convert to full-time employment.

Develop and productionize machine learning and AI solutions across document intelligence, multimodal systems, and foundation models. Responsibilities include dataset and pipeline development, model training and evaluation, GPU experimentation, reusable AI component design, production deployment partnership, monitoring, and communicating technical tradeoffs. The role requires solving open-ended problems in regulated financial services while emphasizing explainability, reproducibility, data governance, reliability, and measurable business impact.

Develop marketing effectiveness analytics using Marketing Mix Modeling, attribution, customer lifetime value, experimentation, and causal inference. Build automated, scalable model pipelines, insight-ready datasets, and self-serve dashboards. Analyze campaigns, support marketing strategy, communicate findings to executives, and lead high-impact projects independently while collaborating cross-functionally.

Own analytical strategy and develop AI/ML models for Zip’s financial products, including cash and rent advances. Lead ambiguous 0-to-1 initiatives using bank transaction data, establish evaluation frameworks, guide risk and growth decisions, and deliver models from experimentation through production. Provide technical direction to data scientists, mentor junior team members, collaborate with engineering, and advise senior stakeholders on model trade-offs. The role requires strong financial services, statistical, research, and machine learning expertise.

Build, train, evaluate, and deploy deep learning models for credit modeling and loss prediction. Conduct representation learning experiments, integrate models into ML pipelines, and own projects from hypothesis through measurable business outcomes. Collaborate with data scientists, engineers, and product partners, communicate findings, and develop agentic tools that accelerate data science workflows.

Design and architect secure, scalable healthcare data systems; create core data models using TUVA, OMOP, and FHIR; build production data pipelines and EMR integrations; establish data quality and governance; optimize performance; deploy cloud infrastructure; and ensure HIPAA and HITRUST compliance. The role requires expert SQL and Python or Scala skills, advanced data warehouse and big-data experience, and at least eight years in data science or data engineering.

Develops data quality checks, metadata standards, and AI use-case inventories for HHS. Cleans and integrates complex datasets, applies machine learning and NLP for automated tagging and classification, evaluates AI governance risks, and produces reporting datasets, dashboards, and recommendations. The role requires translating ambiguous federal policy and reporting requirements into repeatable analytical workflows while collaborating with product, design, engineering, and government stakeholders.

Develop and deploy machine learning and LLM-based solutions for cybersecurity challenges. Responsibilities include analyzing complex datasets, building classification and NLP models, optimizing prompting, embeddings, RAG, and fine-tuning techniques, designing evaluation methodologies, and integrating models into scalable production systems. The role requires collaboration with cybersecurity researchers, software engineers, data engineers, and product managers.

Measures customer engagement impact on pipeline, renewals, account health, and predictive model performance. Conducts baseline, holdout, before-and-after, and control-group analyses; validates customer data and helps tune models. Builds reusable value analyses, dashboards, and reporting for leadership, Customer Success, and Data Science. Requires strong SQL, Python, statistics, experiment design, business communication, and experience translating messy data into trusted insights.

Develop and standardize analytical methods for inferring residence, displacement, and poverty from mobile network operator data. Assess data quality, write technical specifications and tests, guide operator engineering teams, tune statistical methods, and balance accuracy with implementation constraints. Design privacy-preserving analyses, improve data security practices, train internal teams, and support international workshops and emergency-response programs.

The Senior Data Scientist will conduct product analysis, build advanced models and analytics tools, evaluate A/B tests, develop automated dashboards, and generate recommendations for product strategy. The role partners with business stakeholders and Engineering to improve data infrastructure and governance, communicate statistical insights, and support data-driven decisions across Product, Marketing, and Finance.

Own product-led growth analytics across activation, engagement, conversion, monetization, and retention. Lead experimentation, statistical analysis, causal inference, metric development, and proactive opportunity discovery. Build scalable analytical systems, monitoring frameworks, semantic models, and AI-powered tools. Partner with Product, Engineering, and leadership to shape product bets, investment decisions, and roadmap priorities. Work autonomously in a remote-first environment and communicate complex findings through clear, actionable recommendations.

Develop and own advanced machine learning and AI models using bank transaction and cashflow data to enable financial product capabilities, manage risk, and drive profitable growth. Design experiments, build proofs of concept, monitor production models, and collaborate with data and machine learning engineering teams on scalability. Communicate findings and tradeoffs to business stakeholders while applying statistical, research, and financial services expertise.

Lead computational platform development for biological design, optimization, and functional prediction. Collaborate with wet-lab scientists to validate predictions, oversee data infrastructure and computational workflows, and contribute to technology roadmaps, funding proposals, and partnerships. The role requires developing machine learning methods for biological sequence and structure analysis, translating biological problems into computational solutions, and leading technical teams across computational and experimental disciplines.

Build and deploy machine learning models that personalize insurance products, analyze product data, design experiments, and measure model impact. The role owns the full data science lifecycle, including data wrangling, production coding, model monitoring, retraining, and experimentation. Responsibilities also include cross-functional collaboration, code reviews, mentoring data scientists, and improving platform practices.

Own data science for customer-facing product features, including LTV prediction, experimentation, benchmarking, and forecasting. Proactively analyze data to identify customer problems and product opportunities, build and deploy production-grade models, and influence product roadmaps. Partner with Product, Engineering, and Analytics, communicate findings to varied audiences, iterate on shipped features, and lead new data-driven initiatives.

Lead data science and advanced analytics initiatives supporting underwriting, operational performance, and risk management. Develop, validate, deploy, and monitor explainable predictive models in a regulated insurance environment. Translate business needs into scalable analytical solutions, partner with governance and risk stakeholders, lead data scientists and analysts, and communicate insights to senior leaders. The role also supports enterprise data platforms, modern architectures, responsible AI, regulatory compliance, and data-driven organizational change.

Build and operate production calibration and image-processing pipelines for multispectral infrared satellite imagery. Translate calibration algorithms into reliable software with testing, monitoring, alerting, diagnostics, CI/CD, and observability. Analyze pre-launch and on-orbit data, validate calibration coefficients, manage uncertainty budgets, and support calibration campaigns for FireSat and SBEM missions. Collaborate with scientists, instrument engineers, and product teams to ensure radiometric integrity and scientific quality of data products.