Top Senior Data Science Jobs in Denver & Boulder, CO

2 Days AgoSaved
In-Office or Remote
Colorado
Senior level
Senior level
Greentech • Software
Develop and operationalize machine learning and statistical models predicting weather-driven transmission and distribution outages. Integrate weather forecasts, infrastructure data, outage records, and geospatial layers into real-time forecasting pipelines. Apply spatio-temporal, probabilistic, and physics-based modeling to support utility decisions during extreme weather and wildfire events. Collaborate with meteorologists, risk modelers, software engineers, and utility customers while using agentic coding tools to accelerate development and validating scientific correctness.
Top Skills: ArcgisClaude CodeCursorGeopandasGithub CopilotJuliaNumpyPandasPythonPyTorchRScikit-LearnSQLTensorFlow
2 Days AgoSaved
Remote
Colorado
110K-150K Annually
Senior level
110K-150K Annually
Senior level
Financial Services
Develop and deploy statistical and machine learning models supporting credit risk, fraud, collections, and marketing. Responsibilities include data exploration, model design, testing, production monitoring, performance analysis, governance, and stakeholder communication. The role partners with Legal and Compliance, translates business questions into analytical solutions, researches new methods, and provides data-driven recommendations to leadership.
Top Skills: GitPythonSnowflakeSQLXgboost
3 Days AgoSaved
In-Office
Colorado
115K-125K Annually
Senior level
115K-125K Annually
Senior level
Legal Tech
Own production machine learning models end to end, including development, deployment, monitoring, retraining, and staged AWS releases. Build BI dashboards, pricing and margin models, rules-based scoring frameworks, and operational analytics. Partner with engineering on data pipelines and database performance, support business decisions with statistical analysis, and document methodologies for cross-functional teams.
Top Skills: Amazon AuroraAmazon EventbridgeAmazon S3Aws CloudformationAws GlueAws LambdaAws Model RegistryAws SagemakerCatboostClaude CodeConfluenceGithub CopilotLightgbmMetabaseMySQLPandasPytestPythonScikit-LearnSQLXgboost
Reposted 3 Days AgoSaved
Remote
Colorado
143K-304K Annually
Senior level
143K-304K Annually
Senior level
Software • Quantum Computing • Metaverse • Infrastructure as a Service (IaaS)
Lead data science engagements with customers to acquire, clean, analyze, and model data; develop scalable operational models and evaluation methods; coach engineers on best practices; drive solution strategy, ethics, and industry thought leadership; write extensible code and collaborate across teams to deliver cloud-based AI solutions.
Top Skills: AICloud-Based SolutionsMicrosoft CloudOpen-Source
4 Days AgoSaved
In-Office or Remote
Colorado
120K-261K Annually
Senior level
120K-261K Annually
Senior level
Software • Quantum Computing • Metaverse • Infrastructure as a Service (IaaS)
Leads product analytics for Xbox Growth Intelligence, using statistical, econometric, causal inference, experimentation, forecasting, and machine-learning methods to guide product investments. The role analyzes player behavior, engagement, retention, monetization, and ROI; builds experimentation and incrementality frameworks; develops reusable AI-enabled analytical tools; influences senior leaders; and mentors data scientists.
Top Skills: Agentic Ai ToolsPythonRSQL
Reposted 26 Days AgoSaved
Remote
Colorado
Senior level
Senior level
Cloud • Software
Design and deploy predictive forecasting and analytics to support Revenue operations. Build models for forecasting, churn, expansion, and pipeline analytics; create scalable dashboards; partner with Revenue Operations, Finance, and Data Engineering to improve data quality, KPI governance, and executive reporting to drive data-driven decisions and AI readiness.
Top Skills: DashboardsData VisualizationForecastingPredictive AnalyticsPythonSQLStatistical Modeling
Reposted 26 Days AgoSaved
Remote
Colorado
Senior level
Senior level
Healthtech
Own end-to-end modeling for vendor matching, order routing, and supply-chain optimization. Build predictive, causal, RL and OR solutions; design autonomous decision logic; quantify counterfactual impact; ship production models with data engineering; mentor senior data scientists; write technical design docs; partner on quarterly priorities and expand into revenue cycle and finance domains.
Top Skills: Agentic AiCausal InferenceCausal MlDiscrete Event SimulationForecastingGitMachine LearningOperations ResearchPythonQueueing TheoryReinforcement LearningSQL
4 Days AgoSaved
In-Office
Colorado
102K-179K Annually
Senior level
102K-179K Annually
Senior level
Analytics • Consulting
Develop advanced data science and AI/ML solutions using complex healthcare data. Apply statistical modeling, machine learning, NLP, and LLM techniques, including RAG and prompt optimization. Build production-ready workflows integrating models with APIs, data pipelines, enterprise applications, and cloud platforms. Analyze data quality and model performance, communicate findings to technical and executive audiences, and collaborate across product, engineering, clinical, technology, and business teams.
Top Skills: Api IntegrationAWSAzureCerner Ccl-DiscernCerner PowerinsightData PipelinesEpic CaboodleEpic ClarityGenerative AiLarge Language ModelsMachine LearningModel EvaluationNatural Language ProcessingPalantir FoundryPredictive ModelingPrompt OptimizationPythonRRetrieval-Augmented GenerationSASStatistical Modeling
Reposted 27 Days AgoSaved
Remote
Colorado
145K-180K Annually
Senior level
145K-180K Annually
Senior level
Healthtech • Telehealth
Senior individual contributor who drives product analytics, experimentation, and applied modeling. Owns growth and performance analyses, designs experiments with robust statistical evaluation, builds repeatable reporting, and partners with Product, Engineering, Operations, Clinical, and Finance to translate data into actionable product and operational decisions.
Top Skills: BigQueryPandasPythonRedshiftScikit-LearnSnowflakeSQLStatsmodels
28 Days AgoSaved
In-Office
Colorado
99K-225K Annually
Senior level
99K-225K Annually
Senior level
Information Technology
Lead client-facing data science efforts to develop AI/ML solutions (including LLMs/agentic AI), guide teammates, clean and model complex data, evaluate model accuracy, visualize results for leadership, and work on classified networks requiring TS/SCI clearance.
Top Skills: Agentic AiEmrGgplot2GurobiHadoopHiveIotKafkaLlmsMapreduceMySQLNoSQLPlotlyPythonRSeabornSparkSQL
8 Days AgoSaved
In-Office or Remote
Colorado
125K-145K Annually
Senior level
125K-145K Annually
Senior level
Edtech
Lead experimentation and decision science initiatives from problem definition through recommendations. Design and analyze A/B tests, quasi-experiments, matched-market tests, and causal inference studies. Apply advanced statistics, regression, predictive modeling, machine learning, and big-data analysis using Python, R, SQL, and PySpark. Partner with stakeholders, communicate actionable findings, build reproducible workflows, and mentor analysts and junior data scientists.
Top Skills: PysparkPythonRSQL
One Month AgoSaved
Remote
Colorado
185K-231K Annually
Senior level
185K-231K Annually
Senior level
Artificial Intelligence • Software • Analytics • Business Intelligence
Lead and build Neural Earth's geospatial data science function: design and deploy Python-based geospatial models, architect production geospatial data pipelines, validate reproducible methods, translate scientific outputs into customer-ready products, and manage and mentor at least one direct report while advising customers and stakeholders.
Top Skills: CogGdalGeopandasGeoparquetGeotiffNetcdfPythonRasterioShapelyXarray
New

Cut your apply time in half.

Use ourAI Assistantto automatically fill your job applications.

Use For Free
Application Tracker Preview
9 Days AgoSaved
Remote
Colorado
100K-132K Annually
Senior level
100K-132K Annually
Senior level
Healthtech • Social Impact
Build, validate, deploy, monitor, and maintain predictive models and analytical reports. Translate findings for technical and non-technical stakeholders, promote data literacy, deliver training, collaborate on data infrastructure, apply advanced statistical and machine learning methods, and support analytical requests across mental health and crisis care programs.
Top Skills: Amazon RedshiftAmazon SagemakerAWSDeployment PipelinesModel RegistriesPandasPythonRScikit-LearnSnowflakeTidyverseVersion Control
Reposted One Month AgoSaved
Remote
Colorado
150K-195K Annually
Senior level
150K-195K Annually
Senior level
Software • Cryptocurrency • Web3
Partner with Marketing as the embedded data science lead to build marketing measurement, attribution, LTV/ROAS/CAC models, run experiments, analyze the full funnel, create forecasts and dashboards, and influence channel strategy and budget allocation.
Top Skills: Ad PlatformsAppsflyerGoogle AnalyticsLookerMmpPythonRSQLTableau
Reposted One Month AgoSaved
Remote
Colorado
255K-298K Annually
Senior level
255K-298K Annually
Senior level
Consumer Web • Other • Social Media • Software
As the Staff Data Scientist, you will lead the data science function, driving strategy, mentoring peers, and shaping product direction through advanced analytics and experimentation.
Top Skills: PythonSQL
Reposted One Month AgoSaved
Remote
Colorado
Senior level
Senior level
Big Data • Food • Mobile • Payments
Lead company-level measurement and causal strategy, define MAU×ARPU metrics and semantic mart, set scientific standards for experimentation and analysis, own strategic models (MMM, elasticity, forecasting), partner with engineering to productionize analytics, and raise org-wide scientific maturity through governance, templates, and upskilling.
Top Skills: DbtExperimentation PlatformsPythonSnowflakeSQL
9 Days AgoSaved
Remote
Colorado
160K-200K Annually
Senior level
160K-200K Annually
Senior level
AdTech • Fintech • Marketing Tech
Build and deploy machine learning and experimentation systems for personalization, ranking, targeting, attribution, and causal measurement. Develop features and pipelines from transaction and behavioral data, design A/B tests, productionize models with engineering teams, and improve recommendation systems. Translate analytical results into business insights tied to conversion, retention, lift, and ROI while owning projects from problem framing through post-launch evaluation.
Top Skills: AirflowAPIsAWSDbtFeature StoresGCPPandasPythonPyTorchScikit-LearnSparkSQLXgboost
10 Days AgoSaved
Hybrid
Colorado
120K-150K Annually
Senior level
120K-150K Annually
Senior level
3D Printing • Aerospace • Defense • Manufacturing
Leads the design and production deployment of data pipelines, data models, analytical applications, and machine learning solutions for aerospace manufacturing. Partners with IT, engineering, manufacturing, cybersecurity, and business stakeholders to deliver reliable, secure, traceable, and scalable analytics. Develops models for anomaly detection, forecasting, optimization, scheduling, and engine performance; establishes technical standards, testing frameworks, documentation, and governance; troubleshoots production issues; and mentors junior team members.
Top Skills: ErpLlmsMachine LearningMesMlopsPalantir FoundryPythonSQL
11 Days AgoSaved
Remote
Colorado
Senior level
Senior level
Artificial Intelligence • Big Data • Machine Learning
Lead end-to-end predictive analytics and machine learning initiatives, including forecasting, churn prediction, and risk modeling. Translate business needs into scalable ML solutions, build and deploy models on AWS SageMaker, develop production ML pipelines, and oversee monitoring, governance, explainability, and retraining. Collaborate with engineering and MLOps teams, communicate insights to stakeholders, and mentor junior data scientists while providing hands-on technical leadership.
Top Skills: Amazon SagemakerApache AirflowAWSAws LambdaAws Step FunctionsCi/CdGenerative AiInfrastructure As CodeKubeflowMlopsNumpyPandasPythonSagemaker PipelinesScikit-LearnXgboost
12 Days AgoSaved
Remote
Colorado
160K-180K Annually
Senior level
160K-180K Annually
Senior level
Artificial Intelligence • Automotive • Insurance • Software
Own end-to-end data science for a core business area such as growth, product, AI and automation, or strategic partnerships. Define business problems, metrics, reports, analyses, and experiments; generate actionable insights; communicate recommendations; and influence product, growth, finance, and operations leaders to drive measurable outcomes.
Top Skills: ClickhouseGitJupyterhubMetabasePythonSQL
Reposted One Month AgoSaved
Remote
Colorado
Senior level
Senior level
Machine Learning • Software
The Staff Data Scientist will lead the development and deployment of ML and GenAI systems to detect billing errors and fraud in healthcare payments, collaborating with cross-functional teams.
Top Skills: AIData ScienceMachine Learning
12 Days AgoSaved
Remote
Colorado
160K-180K Annually
Senior level
160K-180K Annually
Senior level
Artificial Intelligence • Automotive • Machine Learning • Financial Services
Own the analytical function for a core business area such as growth, product, AI and automation, or strategic partnerships. Define business questions, metrics, reports, analyses, and experiments; generate insights; and drive data-informed decisions with cross-functional stakeholders. The role requires independently structuring ambiguous problems, using SQL or Python, communicating findings clearly, and delivering measurable business impact.
Top Skills: ClickhouseGitJupyterhubMetabasePythonSQL
12 Days AgoSaved
Remote
Colorado
Senior level
Senior level
Big Data • Food • Mobile • Payments
Develop and deploy predictive and causal models for personalization, retention, monetization, and product strategy. Design experimentation and measurement frameworks, analyze user and marketing behavior, quantify business impact, and translate complex findings into strategic decisions. Collaborate with Product, Engineering, Marketing, and Data Product teams to build scalable data solutions. Mentor peers, promote rigorous model validation and governance, and apply Python, SQL, Snowflake, dbt, Airflow, Spark, and AWS to production-ready data science initiatives.
Top Skills: AirflowAWSBayesian InferenceCausal InferenceCcpaDbtExperimentation FrameworksGdprMachine LearningPythonSnowflakeSparkSQL
Reposted One Month AgoSaved
Remote
Colorado
Senior level
Senior level
Cloud • Information Technology • Software • Consulting • Web3
Seeking a skilled Data Scientist/Machine Learning Engineer to develop machine learning models, design AI systems, and collaborate in data analytics. Responsibilities include productionizing models, data engineering, and cross-functional collaboration.
Top Skills: AirflowAWSAzureCi/CdDockerGCPJIRAKubeflowKubernetesMlflowNumpyPandasPlantumlPythonPyTorchSparkTfx
13 Days AgoSaved
In-Office or Remote
Colorado
Senior level
Senior level
Healthtech
Lead the design, development, deployment, and governance of advanced analytics, machine learning, and AI solutions using large healthcare datasets. Responsibilities include data preparation, statistical and predictive modeling, model monitoring, explainability, visualization, stakeholder communication, and translating findings into clinical and operational improvements. The role also mentors data professionals, advises leaders, manages initiative priorities and risks, and promotes responsible AI and Agile practices.
Top Skills: Advanced AnalyticsAgileArtificial IntelligenceData VisualizationDeep LearningFeature EngineeringGenerative AiMachine LearningNatural Language ProcessingOptimizationPredictive ModelingStatistical Modeling
All Filters
JobType
New Jobs
Job Category
Experience
Industry
Company Name
Company Size

Sign up now Access later

Create Free Account