Top Senior Data Science Jobs in Denver & Boulder, CO

6 Days AgoSaved
Remote
Colorado
140K-160K Annually
Senior level
140K-160K Annually
Senior level
Biotech
Lead data strategy and analytics for cognitive assessment studies: design algorithms and models, implement CDISC-compliant data transfers (SDTM/ADaM), produce statistical analysis plans and scientific reports, build and maintain analytics pipelines, dashboards, and visualizations, ensure data quality and QC, and present results to sponsors while managing multiple projects independently.
Top Skills: AdamCdiscMachine LearningPysparkPythonRSdtm
6 Days AgoSaved
Remote
Colorado
150K-170K Annually
Senior level
150K-170K Annually
Senior level
Artificial Intelligence • Automotive • Machine Learning • Financial Services
Embed in a core business area to define the right problems, design metrics, run analyses and experiments, build reports, surface insights, and drive data-informed decisions end-to-end to improve product, growth, AI/automation, or partnerships.
Top Skills: GitJupyter HubMetabasePythonSql (Clickhouse)
6 Days AgoSaved
Remote
Colorado
150K-170K Annually
Senior level
150K-170K Annually
Senior level
Artificial Intelligence • Automotive • Insurance • Software
Embed within a core business area to define problems, build metrics and analyses, run experiments, generate insights from data, and drive decisions end-to-end to improve product, growth, AI/automation, or partnerships.
Top Skills: ClickhouseGitJupyter HubMetabasePythonSQL
Reposted 6 Days AgoSaved
Remote or Hybrid
Colorado
150K-185K Annually
Senior level
150K-185K Annually
Senior level
Artificial Intelligence • Machine Learning • Software • Analytics
The Senior Data Scientist will develop machine learning systems for fraud prevention using behavioral data, collaborate across teams, and mentor junior scientists.
Top Skills: PysparkPythonScikit-LearnSparkSQLTensorFlowXgboost
Reposted 7 Days AgoSaved
Remote
Colorado
Senior level
Senior level
Consumer Web • Software • Business Intelligence
The Senior Data Scientist will develop scalable ML models, analyze large datasets for insights, and collaborate with teams to enhance business performance through data-driven solutions.
Top Skills: HadoopMachine LearningNumpyPandasPythonRScipySpark
Reposted 7 Days AgoSaved
Remote
Colorado
140-150 Annually
Senior level
140-150 Annually
Senior level
Real Estate • Travel • PropTech
The role involves building and validating Marketing Mix Models and geo-experiments, managing measurement infrastructure, and communicating insights to stakeholders.
Top Skills: PythonRSQL
Reposted 8 Days AgoSaved
Remote
Colorado
Senior level
Senior level
Artificial Intelligence • Machine Learning • Natural Language Processing • Software • Generative AI
As a Lead Data Scientist, you'll design experiments, build predictive models, and lead a team while shaping data-driven strategies to enhance AI deployments.
Top Skills: AirflowBigQueryDbtGitLookerPythonSQL
9 Days AgoSaved
Remote
Colorado
97K-124K Annually
Senior level
97K-124K Annually
Senior level
Cloud • Healthtech • Information Technology • Software • Consulting
Design and build predictive models, AI tools, and data visualizations for CMS healthcare initiatives. Analyze quantitative and qualitative data (Medicare claims, public datasets, web analytics), perform feature engineering, anomaly detection, and provide insights to support product design and price-transparency tools. Collaborate with designers, product owners, and engineers in an agile environment.
Top Skills: Decision ForestsK-NnMatlabNaive BayesNumpyPysparkPythonRSparklyrSvmTensorFlowWeka
Reposted 9 Days AgoSaved
Remote
Colorado
177K-230K Annually
Senior level
177K-230K Annually
Senior level
Healthtech • Software
As a Senior Data Scientist, you'll lead projects leveraging data to enhance healthcare outcomes, mentor team members, and align data efforts with business goals.
Top Skills: Machine Learning ToolsPythonSQLStatistical Packages
Reposted 9 Days AgoSaved
In-Office
Colorado
115K-190K Annually
Senior level
115K-190K Annually
Senior level
Big Data • Cloud • Security • Software • Analytics
Seeking a Senior Data Scientist to provide technical expertise for a U.S. Government customer, focusing on data analytics and signals analysis.
Top Skills: Computer ScriptingData AnalyticsData ModelingSignals AnalysisStatistical Analysis
10 Days AgoSaved
Remote
Colorado
Senior level
Senior level
Healthtech
Senior individual contributor who builds statistical models and experiments to optimize acquisition, conversion, retention, and lifetime value. Partners with Product, Marketing, and Engineering to define data requirements, analyze A/B tests, perform cohort and funnel analyses, communicate findings to stakeholders, and mentor junior team members while contributing to analytics best practices.
Top Skills: AWSAzureGCPGitPythonSQL
Reposted 10 Days AgoSaved
Remote
Colorado
165K-206K Annually
Senior level
165K-206K Annually
Senior level
Other
Build and maintain large commercial datasets and predictive/forecasting models (BigQuery, dbt, SQL, Python). Design causal and experimental analyses to measure promotion impact and price elasticity. Partner with commercial, finance, and executive stakeholders to inform pricing, distribution, and investment. Deploy LLMs and AI agents to classify unstructured data and build tools that democratize data access.
Top Skills: Ai AgentsBigQueryDbtLlmsPandasPythonSQL
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Reposted 10 Days AgoSaved
Remote or Hybrid
Colorado
170K-200K Annually
Senior level
170K-200K Annually
Senior level
Artificial Intelligence • Machine Learning • Software • Analytics
As a Senior Data Scientist, you will design and deploy machine learning and graph algorithms to enhance identity trust solutions, own end-to-end projects, and collaborate with product and engineering teams to improve KYC and compliance products.
Top Skills: AirflowAWSAws NeptuneDatabricksDglGraphframesNeo4JPysparkPythonPyTorchPytorch GeometricScalaScikit-LearnSparkSQLTensorFlowXgboost
Reposted 12 Days AgoSaved
Remote
Colorado
210K-240K Annually
Senior level
210K-240K Annually
Senior level
Security • Software
As a Lead Data Scientist, you will design and implement scalable data pipelines and analytics capabilities while leading technical decisions across data workflows, ETL processes, and statistical modeling in the GCP environment.
Top Skills: AirflowApache BeamDataflowDataprocGCPPubsubPysparkPython
Reposted 12 Days AgoSaved
Remote
Colorado
160K-200K Annually
Senior level
160K-200K Annually
Senior level
AdTech • Fintech • Marketing Tech
The Senior Data Scientist will develop machine learning models, conduct A/B tests, and work with behavioral data to enhance customer engagement and partner ROI.
Top Skills: AirflowAWSDbtGCPPythonPyTorchSparkSQLXgboost
Reposted 12 Days AgoSaved
Remote
Colorado
128K-267K Annually
Senior level
128K-267K Annually
Senior level
AdTech • Digital Media • Information Technology • Other
Lead data science for Yahoo Mail subscriptions: analyze acquisition, conversion, pricing, retention, and churn; design and analyze A/B and multivariate experiments; build predictive and clustering models; partner with product, engineering, design, and business teams to deliver data-driven growth and monetization insights.
Top Skills: BigQueryComscoreConfluenceData AiExperimentation Frameworks (A/B TestingHadoopHiveJIRALookerMultivariate Testing)PythonSimilarwebSparkSQLTableau
Reposted 15 Days AgoSaved
Remote
Colorado
Senior level
Senior level
Fintech • Mobile • Payments • Software
Proactively explore RevenueCat's data to identify product opportunities, translate ambiguous problems into analyses and production-grade predictive/descriptive models, partner with Product and Engineering to ship data-powered features (LTV prediction, experimentation, benchmarking), define statistical approaches, iterate on models in production, and communicate insights to technical and non-technical audiences.
Top Skills: AWSDbtPostgresPythonSnowflakeSQL
Reposted 16 Days AgoSaved
Remote
Colorado
Senior level
Senior level
Healthtech • Professional Services • Biotech • Pharmaceutical
The Senior Data Scientist will manage data collection, design study protocols, train juniors, lead report development, and support innovative analytics tools.
Top Skills: Data AnalysisMachine LearningProject Management FrameworksStatistical Analysis
Reposted 16 Days AgoSaved
Remote
Colorado
Senior level
Senior level
Healthtech • Professional Services • Biotech • Pharmaceutical
The Senior Data Scientist oversees data collection and preparation, designs study protocols, leads report development, trains junior employees, and manages project workstreams while collaborating with team members to optimize business performance.
Top Skills: Data ManagementProject Management FrameworksQuantitative Analysis
Reposted 16 Days AgoSaved
Remote
Colorado
106K-168K Annually
Senior level
106K-168K Annually
Senior level
Other • Social Impact
The Senior Data Scientist will integrate data from various sources, analyze web performance, and provide insights for strategic decision-making. Responsibilities include developing automated systems for content coverage, tracking metrics, and designing experiments to assess new initiatives' impact.
Top Skills: AhrefsBigQueryDruidHiveJupyterMatomoPrestoPythonQuartoSemrushSparkSQLSuperset
18 Days AgoSaved
Remote
Colorado
Senior level
Senior level
AdTech • Big Data • Consumer Web • Digital Media • Marketing Tech
Own end-to-end data science for a priority vertical (starting with Insurance): frame business problems, build and validate models, partner with ML engineering for deployment, monitor live ROAS performance, and drive measurable revenue and lead quality improvements.
Top Skills: AWSCollaborative FilteringDeep LearningEmbeddingsGoogle AdsLlmsLookerLtv ModelingMeta AdsMulti-Armed BanditPythonRanking AlgorithmsRecommendation SystemsReinforcement LearningSQL
Reposted 18 Days AgoSaved
In-Office
Colorado
Senior level
Senior level
Logistics • Transportation
Lead the development of appraisal and pricing capabilities using data science to automate valuation decisions. Collaborate across teams for insights into pricing and operational strategies.
Top Skills: Bayesian ModelingPythonSQL
Reposted 18 Days AgoSaved
Remote
Colorado
150K-200K Annually
Senior level
150K-200K Annually
Senior level
eCommerce
The Senior Data Scientist will develop models and analyses for risk and revenue decisions, collaborating with various teams to optimize funding for eCommerce.
Top Skills: BigQueryPythonSnowflakeSQL
Reposted 18 Days AgoSaved
Remote
Colorado
183K-183K Annually
Senior level
183K-183K Annually
Senior level
Big Data • Machine Learning • Social Impact • Software
Lead end-to-end data science projects including predictive modeling, algorithm design, and data pipelines. Build campaign-focused models (turnout, partisanship), perform exploration and visualization, translate insights into memos/presentations, collaborate with engineering to productionize models, mentor junior data scientists, and prototype emerging AI solutions for product impact.
Top Skills: GitPythonSQL
19 Days AgoSaved
In-Office or Remote
Colorado
135K-155K Annually
Senior level
135K-155K Annually
Senior level
Digital Media • News + Entertainment • Business Intelligence
Lead data science work embedded in the newsroom: identify high-impact problems, build and productionize predictive and explanatory models, own core metrics/measurement, apply causal inference and experimentation, translate findings for senior stakeholders, and mentor junior data team members to improve analytic standards and adoption.
Top Skills: AirflowBigQueryDbtGitPythonSnowflakeSQL
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