Top Senior Machine Learning Jobs in Denver & Boulder, CO

Reposted YesterdaySaved
Easy Apply
Remote
Colorado
Easy Apply
232K-310K Annually
Senior level
232K-310K Annually
Senior level
Big Data • Fintech • Mobile • Payments • Financial Services
Lead the development of fraud prediction models using machine learning, collaborating across teams to build, scale, and monitor models in production.
Top Skills: AirflowCatboostKubeflowLightgbmMachine LearningMlflowPythonPyTorchSparkXgboost
Reposted YesterdaySaved
Easy Apply
Remote
Colorado
Easy Apply
200K-275K Annually
Senior level
200K-275K Annually
Senior level
Big Data • Fintech • Mobile • Payments • Financial Services
Lead a team of ML engineers to develop fraud detection models, defining strategies, driving model evolution, and ensuring effective integration with cross-functional teams.
Top Skills: Data PipelinesDeep LearningGradient-Boosted TreesMachine LearningRepresentation LearningScalable SystemsTransformer-Based Models
Reposted 9 Days AgoSaved
Easy Apply
Remote
Colorado
Easy Apply
225K-245K Annually
Senior level
225K-245K Annually
Senior level
Healthtech • Software
The Staff Machine Learning Engineer will lead ML initiatives, develop ML systems, collaborate with cross-functional teams, and mentor junior engineers to optimize healthcare intake workflows using advanced machine learning techniques.
Top Skills: AWSCloud PlatformsDeep LearningMachine LearningPythonPyTorch
Reposted 10 Days AgoSaved
In-Office
Colorado
124K-206K Annually
Senior level
124K-206K Annually
Senior level
Aerospace • Artificial Intelligence • Computer Vision • Software • Analytics • Defense • Big Data Analytics
The Staff Applied AI Engineer will develop decision intelligence systems using machine learning and optimization, focusing on improving planning decisions and operational efficiency. Responsibilities include building models for revenue attribution, designing decision-support systems, and ensuring security in AI-driven capabilities.
Top Skills: Machine LearningOptimizationPythonReinforcement LearningSimulation
Reposted 12 Days AgoSaved
Easy Apply
Remote
Colorado
Easy Apply
200K-275K Annually
Senior level
200K-275K Annually
Senior level
Big Data • Fintech • Mobile • Payments • Financial Services
Manage a team of ML engineers to build and optimize Affirm's economic decisioning engine using advanced ML techniques. Collaborate across teams, provide technical leadership, and mentor engineers while driving a cohesive long-term ML strategy.
Top Skills: Agentic MlDeep LearningMachine LearningTransformersTree-Based Models
Reposted 16 Days AgoSaved
Easy Apply
Remote
Colorado
Easy Apply
196K-247K Annually
Senior level
196K-247K Annually
Senior level
Artificial Intelligence • Fintech • Healthtech • Software
Lead the development of machine learning systems for Cedar Pay's Personalization Engine, manage ML engineers, and ensure ML model effectiveness.
Top Skills: Machine LearningPythonSQL
Reposted 3 Days AgoSaved
Remote
Colorado
150K-215K Annually
Senior level
150K-215K Annually
Senior level
Artificial Intelligence • Machine Learning • Software • Defense
Develop scalable machine learning services for data enrichment, managing the ML lifecycle from model training to deployment, and ensuring performance and reliability standards.
Top Skills: Hugging FaceKubernetesOnnxPyTorchRayTensorFlowTensorrtVllm
Reposted 5 Days AgoSaved
Easy Apply
Remote
Colorado
Easy Apply
232K-310K Annually
Senior level
232K-310K Annually
Senior level
Big Data • Fintech • Mobile • Payments • Financial Services
As a Senior Staff Machine Learning Engineer at Affirm, you will lead complex ML system design and implementation, mentor engineers, and drive innovative ML strategies for financial services.
Top Skills: KubeflowMlflowPythonPyTorchRaySparkXgboost
Reposted 21 Hours AgoSaved
Remote
Colorado
Senior level
Senior level
Artificial Intelligence • Software • Analytics
As a Senior Machine Learning Engineer, you will enhance diffusion models, conduct research, collaborate on system implementations, and communicate findings effectively.
Top Skills: AIAWSAzureDeep LearningDiffusion ModelsGansGCPMachine LearningMultimodal LlmsPyTorchVaes
Reposted YesterdaySaved
In-Office or Remote
Colorado
225K-260K Annually
Senior level
225K-260K Annually
Senior level
Robotics
Develop and scale machine learning training systems for robotics data, optimize training pipelines, and collaborate with ML researchers to enhance autonomy models.
Top Skills: Distributed Training FrameworksMachine LearningNeural NetworksPython
Reposted 7 Days AgoSaved
Easy Apply
Remote or Hybrid
Colorado
Easy Apply
179K-319K Annually
Senior level
179K-319K Annually
Senior level
Artificial Intelligence • Cloud • Computer Vision • Hardware • Internet of Things • Software
As a Staff Machine Learning Engineer, you will design AI products on Edge devices, optimize ML model performance, and work with large-scale datasets, collaborating across teams to deliver impactful solutions.
Top Skills: C++PythonRayRustSpark
Reposted 2 Days AgoSaved
In-Office or Remote
Colorado
Senior level
Senior level
Fintech • Financial Services
Lead end-to-end research applying advanced ML/DL (transformers, GNNs, RL, ensembles) to generate alpha across digital asset markets, build production-grade pipelines, prevent leakage/overfitting, analyze microstructure and on-chain data, and mentor junior researchers.
Top Skills: Attention MechanismsC++Deep LearningEnsemble MethodsGraph Neural NetworksLightgbmMachine LearningOn-Chain DataPythonReinforcement LearningRustTransformersXgboost
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Reposted 2 Days AgoSaved
In-Office or Remote
Colorado
205K-275K Annually
Senior level
205K-275K Annually
Senior level
Sales
Lead the data and ML product vision: define roadmap, prototype models on noisy behavioral datasets, translate signals into user-facing features, partner with engineering to productionize ML, and generate insights to inform product roadmaps.
Top Skills: AIData EngineeringExperimentationMachine LearningPredictive Analytics
3 Days AgoSaved
Remote
Colorado
144K-299K Annually
Senior level
144K-299K Annually
Senior level
AdTech • Digital Media • Information Technology • Other
Conduct ML research for query understanding, ranking, clustering, and AI-powered search. Prototype and productionize algorithms, define data and evaluation requirements, design scalable systems, collaborate with engineers, run experiments, and publish patents/papers to integrate state-of-the-art ML into Yahoo Search products.
Top Skills: Deep LearningJavaMachine LearningNatural Language ProcessingPythonScalaSearch Ranking
Reposted 3 Days AgoSaved
Remote
Colorado
Senior level
Senior level
Artificial Intelligence • Healthtech • Machine Learning
As Director of AI/ML, lead the ML organization, set technical vision, mentor a high-performing team, and contribute to model development and production deployment.
Top Skills: Data WarehousingDatabricksEhrFhirHl7Machine LearningRedshiftSnowflake
Reposted 3 Days AgoSaved
Remote
Colorado
160K-220K Annually
Senior level
160K-220K Annually
Senior level
Artificial Intelligence • Fintech • Machine Learning • Software • Financial Services
Embed with clients to gather requirements and design AI-driven solutions for fraud and fincrime. Architect, train, evaluate, and deploy custom AI agents and workflows, optimize model performance, establish risk metrics and evaluation pipelines, and collaborate with engineering/product teams to scale into production.
Top Skills: Ai AgentsEvaluation PipelinesFine-TuningMachine LearningModel DeploymentPrompt EngineeringPythonSQL
Reposted 11 Days AgoSaved
Remote or Hybrid
Colorado
141K-238K Annually
Senior level
141K-238K Annually
Senior level
Artificial Intelligence • Cloud • Sales • Security • Software • Cybersecurity • Data Privacy
The Staff Machine Learning Engineer will design and build scalable ML systems, mentor engineers, and drive AI strategy at SailPoint, focusing on AI-powered identity security solutions.
Top Skills: AirflowAWSCloudbeesDbtJenkinsPythonPyTorchQlikScikit-LearnSnowflakeSparkSQLTableauTensorFlow
Reposted 7 Days AgoSaved
Remote
Colorado
Senior level
Senior level
Machine Learning • Software
The Senior Machine Learning Engineer will design, prototype, build AI systems, evaluate ML models, and improve Vectara's AI Agents with a focus on reliability and performance.
Top Skills: Deep LearningMachine LearningNatural Language ProcessingPandasPythonPyTorchRetrieval-Augmented GenerationTransformers
Reposted 7 Days AgoSaved
Remote
Colorado
225K-255K Annually
Senior level
225K-255K Annually
Senior level
Security
As a Machine Learning Engineer, you'll design, build, and maintain models to detect security threats, ensuring model efficiency and aligning initiatives with business goals.
Top Skills: AWSDockerGCPGenerative AiKubernetesLlmsMachine LearningPandasPythonScikit
Reposted 7 Days AgoSaved
Remote
Colorado
Senior level
Senior level
AdTech
Lead the Performance ML team at MNTN, driving strategy and deployment of predictive models for ad technology, while managing, mentoring, and scaling engineering teams.
Top Skills: Data ScienceGoogle Cloud PlatformMachine Learning
Reposted 14 Days AgoSaved
Remote or Hybrid
Colorado
122K-160K Annually
Senior level
122K-160K Annually
Senior level
Edtech • Information Technology • Software
The Machine Learning Engineer develops production ML algorithms and recommendation systems, collaborates with teams, and optimizes user experiences.
Top Skills: DockerKubernetesNode.jsPythonTensorFlowTypescript
Reposted 9 Days AgoSaved
Remote
Colorado
150K-200K Annually
Senior level
150K-200K Annually
Senior level
Healthtech • Software
As a Senior Machine Learning Engineer, you will design and implement systems for ML and NLP, optimizing models and tools for Clover's healthcare solutions.
Top Skills: LlmMachine LearningNatural Language ProcessingNumpyPandasPythonPyTorchScikit-LearnTensorFlow
Reposted 9 Days AgoSaved
Remote
Colorado
120K-195K Annually
Senior level
120K-195K Annually
Senior level
Gaming
The Senior Machine Learning Engineer will develop core ML models, manage data pipelines, and collaborate with stakeholders to deliver scalable ML solutions.
Top Skills: BeamBigQueryData EngineeringGCPIcebergJavaKubernetesMachine LearningParquetPythonScalaSnowflakeSparkSQL
Reposted 9 Days AgoSaved
Remote
Colorado
175K-300K Annually
Senior level
175K-300K Annually
Senior level
Software
The Senior Machine Learning Researcher will design experiments, research new algorithms, and collaborate on deploying models for computer vision and robotics applications.
Top Skills: AlgorithmsComputer VisionDeep LearningMachine LearningMlops
11 Days AgoSaved
In-Office or Remote
Colorado
110K-135K Annually
Senior level
110K-135K Annually
Senior level
Legal Tech
Advise clients on antitrust eDiscovery compliance using machine learning and generative AI. Build and validate TAR/AI models (Epiq AI, Relativity, Reveal, Brainspace), craft LLM prompts, draft defensible protocols, train/transfer workflows to review teams, and support client-facing, pre-sales, and thought-leadership activities. Must manage multiple projects and meet deadline-driven schedules.
Top Skills: BrainspaceClaudeCopilotEpiq Ai (Eai)GeminiGenerative AiHarveyLarge Language ModelsMachine LearningMicrosoft O365Power BIPythonRelativity (ServerRelativity Active LearningRelativity AirRelativityone)Reveal AiSQLTar 1.0Tar 2.0
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