Top Remote Machine Learning Jobs in Denver & Boulder, CO

The Senior Machine Learning Researcher will design experiments, research new algorithms, and collaborate on deploying models for computer vision and robotics applications.

Design, train, and evaluate advanced machine learning models for autonomous driving, simulation, and ML platforms. Lead small cross-functional engineering teams, establish data and experiment practices for petabyte-scale training, address long-tail model failures, and work with multimodal datasets exceeding 100TB. The role requires commercial robotics experience, mentoring capability, expertise in VLA or generative world models, Python/PyTorch, sensor processing, and potentially edge deployment.

As a Staff Machine Learning Engineer, you will design AI products on Edge devices, optimize ML model performance, and work with large-scale datasets, collaborating across teams to deliver impactful solutions.

The AI/Machine Learning Specialist designs and implements AI solutions, collaborates with cross-functional teams, and continuously improves ML processes.

Design and implement machine learning models to solve business problems, analyze data for insights, and optimize model performance.

Designs and operates production multi-agent AI systems, LLM workflows, scoring and optimization algorithms, and closed-loop autonomous processes. Responsibilities include AI model evaluation, production monitoring, governance, third-party AI integration, federated data retrieval, and identifying patentable inventions. The role requires deep machine learning expertise, algorithm development, and deployment experience across complex operational environments.

The Sr. Machine Learning Engineer will develop and deploy ML solutions for healthcare, manage data pipelines, and work with large datasets to enhance healthcare delivery.

As a Staff Applied ML Scientist, you will develop and maintain fraud detection models, conduct research on fraud types, and collaborate across teams to drive product development and real-time decision-making.

As a Senior Applied ML Scientist, you'll develop fraud detection models, research new fraud types, and write production code while collaborating across teams to enhance SentiLink's identity verification solutions.

Leads architecture and development of production-grade mapping and localization ML systems for autonomous vehicles. Designs neural models for detection, segmentation, tracking, depth estimation, 3D reconstruction, and semantic mapping; owns data strategy, evaluation, deployment, and fleet validation. Mentors engineers, drives technical roadmaps, collaborates cross-functionally, and advances vectorized HD mapping, foundation models, and real-time optimization.

Develop and optimize large-scale advertising ranking models for CTR and CVR prediction, calibration, user representations, and sequence modeling. Own machine learning systems end to end, including data pipelines, feature engineering, training, evaluation, deployment, and maintenance. Collaborate with platform, product, data science, and engineering teams to run experiments and improve advertiser outcomes, revenue, and user relevance. Apply deep learning and recommendation techniques within production latency, reliability, and cost constraints.

Design, productionize, and deploy machine learning forecasting models for ad inventory and campaign performance in low-latency, real-time advertising environments. Build scalable simulation, budgeting, and pacing systems; collaborate with cross-functional teams to deploy models at scale and optimize ad monetization.

Lead the hands-on development of Vida’s secure data and AI/ML platform, including ingestion, data modeling, MLOps, model serving, feature pipelines, LLM integrations, DevOps, observability, and infrastructure. Partner with security and IT to protect sensitive health data and meet HIPAA/HITRUST-aligned controls while establishing scalable engineering patterns across the organization.

Conduct machine learning research operations using existing infrastructure. Characterize neural network quality, failure modes, and edge cases; coordinate experiments with researchers; manage concurrent experiments and deadlines; review results; recommend theoretical or process improvements; and prepare technical reports communicating qualitative and quantitative findings.

Design, train, and productionize machine learning models for fraud and identity risk across the full ML lifecycle. Research new fraud types, perform feature engineering and labeling, write production-ready code for real-time decisioning, monitor models, and provide analyses to inform product, sales, and data acquisition.

Build and deploy LLM-powered agents and workflows using production templates, pipelines, and guardrails. Develop comprehensive evaluations, integrate with business systems and data sources, instrument cost and quality telemetry, and collaborate with business users to iterate within defined scopes. The role requires strong Python and TypeScript skills, production experience with agents, RAG, and tool use, as well as expertise in prompt and context engineering.

Develops AI/ML prototypes, APIs, microservices, integrations, and lightweight user interfaces for federal and DoD-aligned mission workflows. The role integrates and optimizes machine learning models for dashboards and applications, supports data ingestion and preprocessing, validates performance, and helps transition models into production. Collaboration with data scientists, architects, developers, PMO leadership, and cybersecurity teams is required. The position requires five years of relevant experience, a bachelor’s degree, ITIL v4 Foundation certification, and Public Trust or active Secret clearance.

Designs AI/ML pilots, predictive analytics and anomaly detection models, behavioral analytics, content classification, personalization algorithms, and end-to-end machine learning pipelines. Develops prototypes and production-ready solutions, evaluates AI technologies, supports experimentation, integrates ML insights into dashboards, and ensures model governance, explainability, bias mitigation, accuracy, and security compliance in federal and DoD-aligned environments.

Develop, deploy, and optimize scalable machine learning solutions, including predictive models, deep learning systems, data pipelines, and model-serving infrastructure. Monitor model performance, manage retraining and lifecycle processes, ensure quality and compliance, and support responsible AI practices. Collaborate with data scientists, engineers, product teams, and business stakeholders while researching emerging AI technologies and improving AI architectures.

Leads the architecture, development, deployment, and optimization of enterprise machine learning solutions. Responsibilities include designing scalable ML systems, developing predictive models, supporting MLOps and model lifecycle management, improving data quality and feature engineering, implementing governance and validation frameworks, and mentoring technical teams. The role also contributes to AI strategy, innovation initiatives, responsible AI practices, and organizational modernization.

Build, ship, and own end-to-end ML models for vendor matching, order routing, and supply-chain optimization. Partner with data engineering to productionize models, quantify impact, document work, and implement decision logic components toward agentic AI in a fast-moving healthcare startup environment.

Design and productionize ML models and agentic systems for intraday financial alpha generation. Build data pipelines, experiment frameworks, and portfolio optimization methods. Collaborate with quants and engineers to move models from research to live trading environments.

Lead causal inference and measurement efforts for payments, build and evaluate ML/AI and LLM-based models, optimize fraud mitigation and loss strategies, simulate interventions, and communicate findings to stakeholders to drive product and risk decisions.

Join Trexquant as a Global Alpha Researcher to develop trading signals, implement research, and apply machine learning for alpha discovery.

Lead end-to-end deployments of AI for hotel revenue teams: integrate PMS/CRS/RMS, ship ML/optimization models and agentic workflows, validate recommendations with revenue managers, define metrics, drive adoption, and hire/mentor the forward deployed engineering team.