Top Remote Machine Learning Jobs in Denver & Boulder, CO

Develop and operate production ML and AI systems powering patient experiences such as matching, ranking, recommendations, onboarding, and personalization. Build reusable ML infrastructure, pipelines, evaluation, observability, and model-serving capabilities. Provide technical leadership across the ML lifecycle, guide architecture, evaluate custom versus foundation-model approaches, and partner with ML and Patient Engineering teams to deliver reliable, scalable AI products.

Leads the AI Engineering team across applied AI features and foundational ML infrastructure. Responsibilities include managing Senior and Staff engineers, hiring and coaching, deploying LLM-powered capabilities, building MLOps and AI observability platforms, balancing product delivery with platform investment, and ensuring privacy, compliance, evaluation rigor, and clinical safety in production systems.

Develop and maintain production machine learning models, build scalable training and serving technologies, optimize real-time and batch ML pipelines, and monitor model performance and drift. The role involves deep neural networks, recommendation systems, automated retraining, ML research, engineering excellence, and communicating technical concepts to diverse audiences. Candidates need 6+ years of industry ML experience, strong coding skills, and experience deploying neural networks at scale.

Build and operate production machine learning systems for Safety AI, including low-latency APIs, data pipelines, model serving, evaluation, monitoring, and rollout infrastructure. Process large-scale camera and telematics data, optimize cloud and edge-to-cloud execution, track model performance and drift, and partner with applied scientists, firmware engineers, platform teams, and product managers to deliver reliable safety features.

Develop autonomy evaluation metrics, statistical and machine-learning analyses, dashboards, and pipelines for simulation and on-road autonomous vehicle testing. Analyze perception, prediction, and planning performance; identify anomalous behavior and critical scenarios; apply VLMs and LLMs where appropriate; and support release gating and safety decisions. The role requires production Python, C++ debugging, technical leadership, cross-functional collaboration, and rigorous software engineering practices.

Own the end-to-end architecture, development, deployment, evaluation, and operations of AI and machine learning systems. Build predictive ordering models, agentic workflow copilots, retrieval and evaluation infrastructure, safety guardrails, and responsible AI practices. Prioritize AI initiatives based on business outcomes, establish model governance and production standards, advise product and engineering leadership, and mentor experienced contributors.

Develop and optimize machine learning-based underwriting, settlement, and collection strategies across multiple consumer credit products. Build predictive models, decision systems, experimentation frameworks, and AI-assisted workflows using financial and behavioral data. Partner with Product, Engineering, Finance, Legal, and Compliance to improve portfolio performance, member outcomes, and responsible access to credit.

Develops and productionizes deep learning and machine learning perception models for robotics and recycling sortation. Responsibilities include experimenting with neural network architectures, designing computer vision solutions, conducting statistical experiments, deploying successful models, collaborating with data, modeling, and cloud infrastructure teams, and improving ML infrastructure.

Leads Lyra Health’s AI/ML engineering roadmap, scales and mentors machine learning teams, and drives production-grade systems for clinical applications. Responsibilities include people leadership, quarterly planning, technical architecture, design reviews, model governance, ML SDLC oversight, and deployment of reliable microservices on Kubernetes. The role partners with product, data science, and clinical stakeholders while ensuring safety, operational excellence, cloud scalability, and compliance for sensitive healthcare data.

Leads Tala’s Machine Learning Engineering team in building and operating platforms for model development, real-time inference, streaming features, batch processing, deployment, monitoring, and production reliability. Manages and develops 4–6 engineers, owns delivery and prioritization, provides architectural leadership, improves engineering practices and SLOs, and partners with Data Science, Data Engineering, Product, Credit, and Business Development teams.

Leads and develops a perception and machine learning engineering team building computer vision, sensor fusion, tracking, detection, and scene-understanding capabilities for autonomous systems. Owns roadmap planning, technical decisions, delivery, model development and deployment workflows, field readiness, hiring, performance management, and cross-functional execution with autonomy, embedded, data, hardware, product, programs, and field operations teams.

Design, build, and maintain optimization technology, full-stack systems, and data-intensive scheduling infrastructure. Improve optimization algorithms using linear optimization, machine learning, and generative AI. Lead complex technical initiatives, establish testing and observability, support scalable operations, troubleshoot customer issues, participate in on-call rotations, and mentor engineers while partnering closely with product and engineering teams.

The Staff ML Engineer will design and operate Samsara's ML platform, collaborating with teams to enhance ML features and improve safety outcomes. Responsibilities include overseeing system reliability, leading technical direction, and mentoring engineers.

Build and scale production AI systems for Prophetic’s real estate intelligence platform. Responsibilities include developing agentic systems, data pipelines, inference workflows, evaluation benchmarks, geospatial processing, and machine learning applications across hundreds of millions of records. The role requires shipping reliable Python services, optimizing throughput and cost, integrating research into products, and collaborating with engineering and product teams.

Design, develop, and implement AI/ML models; analyze large datasets; integrate AI solutions into existing systems; apply MavLink for autonomous systems; collaborate across teams and improve ML development processes.

Lead the development of machine learning systems for Cedar Pay's Personalization Engine, manage ML engineers, and ensure ML model effectiveness.

Staff-level ML and agent systems engineer responsible for production model lifecycles, multi-step agentic systems, evaluations, retrieval and context engineering, and model cost and latency optimization. The role owns technical direction for Code Understanding products, improves model and agent quality, establishes evaluation and monitoring standards, mentors engineers, collaborates with customers, and delivers reliable AI-powered developer experiences at enterprise scale.

Designs, builds, and operationalizes enterprise AI, generative AI, machine learning, and agentic AI solutions. Develops integrations, orchestration services, reusable tooling, deployment pipelines, monitoring, and governance controls. Partners with architecture, platform, data, and product teams to deliver scalable, secure, compliant AI capabilities across the organization.

The Staff Machine Learning Engineer will lead ML initiatives, develop ML systems, collaborate with cross-functional teams, and mentor junior engineers to optimize healthcare intake workflows using advanced machine learning techniques.

Own the full machine learning lifecycle for search ranking and retrieval, including model training, deployment, serving, feature pipelines, evaluation frameworks, hybrid lexical-vector retrieval, large-scale embedding inference, query understanding, and permissions-aware multi-tenant search. Collaborate with infrastructure, AI, and backend teams to improve search relevance across ClickUp’s platform.

Partner with healthcare clients to discover, design, and deliver production-grade AI/LLM solutions. Architect cloud-native systems, build and deploy ML/LLM applications, prototype rapidly, troubleshoot distributed systems, and lead client engagements to drive measurable business outcomes while collaborating across product, platform, and engineering teams.

Design, productionize, and scale machine learning and optimization models, pipelines, libraries, and deployment platforms. Partner with data scientists, engineers, product managers, and business stakeholders to deliver ML capabilities, personalization systems, and reusable end-to-end workflows. Establish ML engineering best practices, troubleshoot data pipelines, mentor junior professionals, and help define BetterHelp’s ML platform strategy.

Build and maintain computer vision and machine learning pipelines for automated device inspection, grading, and quality assessment. Responsibilities include data preparation, feature engineering, model training and evaluation, production Python development, monitoring, annotation workflows, documentation, code reviews, and collaboration with product and operations teams. The role supports the full ML lifecycle and offers increasing ownership under senior engineering guidance.

Design and productionize machine learning, deep learning, LLM, personalization, recommendation, search, and retrieval systems. Collaborate with product, engineering, and analytics teams to deploy AI solutions that improve customer experiences, business growth, and operational efficiency. The role requires driving projects from ideation through deployment and delivering measurable business impact in a fast-moving fintech environment.

Leads AI/ML engineering teams across platform and delivery pods, managing employees and contractors while enforcing code, agent, review, and production-readiness standards. Partners on reusable templates, pipelines, and evaluation processes, ensures adoption across teams, manages contractor performance and conversion, and removes delivery blockers. The role requires hands-on credibility reviewing agent architectures, prompts, and evaluation suites, with experience operating as a player-coach in fast-moving organizations.