Top Remote Machine Learning Engineer Jobs in Denver & Boulder, CO

The Staff Machine Learning Engineer will design and build scalable ML systems, mentor engineers, and drive AI strategy at SailPoint, focusing on AI-powered identity security solutions.

Own the research-to-production pipeline: harden training/evaluation workflows, build packaging/deployment tooling, design release gates, optimize inference and serving for latency/throughput, establish benchmarking and validation, and instrument feedback from production to accelerate research iteration.

Develops and productionizes deep learning and machine learning perception models for robotics and recycling sortation. Responsibilities include experimenting with neural network architectures, designing computer vision solutions, conducting statistical experiments, deploying successful models, collaborating with data, modeling, and cloud infrastructure teams, and improving ML infrastructure.

Lead end-to-end ML systems for identity verification, including document authenticity, face match, liveness and deepfake detection. Build GNN-based identity graphs, behavioral/device-intelligence models, vendor benchmarking/evaluation, and production enforcement. Mentor engineers and align ML architecture with Product, Compliance, Risk, and Security stakeholders.

Build and operate production machine learning systems for Safety AI, including low-latency APIs, data pipelines, model serving, evaluation, monitoring, and rollout infrastructure. Process large-scale camera and telematics data, optimize cloud and edge-to-cloud execution, track model performance and drift, and partner with applied scientists, firmware engineers, platform teams, and product managers to deliver reliable safety features.

Develop, implement, and deploy scalable machine learning models for healthcare solutions. Collaborate cross-functionally to integrate models, analyze data to improve performance, ensure data quality, and stay current with ML advancements to support patient care and operational efficiency.

Design, develop, and implement AI/ML models; analyze large datasets; integrate AI solutions into existing systems; apply MavLink for autonomous systems; collaborate across teams and improve ML development processes.

Design, build, and deploy production-grade ML systems for ICS/xOT cybersecurity, including threat detection, anomaly detection, NLP/LLM applications, and scalable data pipelines with observability and MLOps practices for cloud and on-prem environments.

Design, build, and deploy production ML systems for ICS/xOT cybersecurity, including threat detection, anomaly detection, NLP/LLM features, data pipelines, observability, MLOps, and containerized deployments across cloud and on-prem environments.

As a Staff Machine Learning Engineer, you will design AI products on Edge devices, optimize ML model performance, and work with large-scale datasets, collaborating across teams to deliver impactful solutions.

Conduct machine learning research operations using existing infrastructure. Characterize neural network quality, failure modes, and edge cases; coordinate experiments with researchers; manage concurrent experiments and deadlines; review results; recommend theoretical or process improvements; and prepare technical reports communicating qualitative and quantitative findings.

Leads the design, development, deployment, and optimization of generative AI and machine learning solutions. Architects agentic LLM workflows, integrates AI with enterprise systems, performs data engineering and analysis, and applies secure software practices for production deployment. Develops reusable AI frameworks, implements responsible AI controls, communicates technical concepts to stakeholders, and mentors engineers and data scientists. The role requires expertise in LLMs, RAG, prompt engineering, fine-tuning, model evaluation, and AI governance.

The Staff Machine Learning Engineer will lead ML initiatives, develop ML systems, collaborate with cross-functional teams, and mentor junior engineers to optimize healthcare intake workflows using advanced machine learning techniques.

Build and ship production LLM-powered agents, workflows, and integrations using platform templates, pipelines, and guardrails. Develop comprehensive evaluation suites, integrate business systems and data sources, instrument cost and quality telemetry, and collaborate with business users to iterate within defined scopes. Requires extensive software engineering experience, production LLM application expertise, strong Python and TypeScript skills, API craftsmanship, prompt and context engineering, and a commitment to guardrails and evaluation.

Build and deploy LLM-powered agents and workflows using production templates, pipelines, and guardrails. Develop comprehensive evaluations, integrate AI systems with business data sources, and instrument cost and quality telemetry. Collaborate with business users to rapidly iterate within defined scopes while maintaining production standards. The role requires extensive software engineering experience, production LLM application development, strong Python and TypeScript skills, API expertise, and retrieval or healthcare data experience as desirable qualifications.

Build and deploy LLM-powered agents, workflows, and integrations using production templates, pipelines, and guardrails. Develop comprehensive evaluation suites, integrate with business systems and data sources, and instrument solutions for cost and quality telemetry. Collaborate with business users to iterate rapidly within defined scopes. The role requires strong Python and TypeScript skills, production LLM application experience, API development, prompt and context engineering, and retrieval expertise.

Build and deploy LLM-powered agents and workflows using production templates, pipelines, and guardrails. Develop comprehensive evaluations, integrate with business systems and data sources, instrument cost and quality telemetry, and collaborate with business users to iterate within defined scopes. The role requires strong Python and TypeScript skills, production experience with agents, RAG, and tool use, as well as expertise in prompt and context engineering.

Develops AI/ML prototypes, APIs, microservices, integrations, and lightweight user interfaces for federal and DoD-aligned mission workflows. The role integrates and optimizes machine learning models for dashboards and applications, supports data ingestion and preprocessing, validates performance, and helps transition models into production. Collaboration with data scientists, architects, developers, PMO leadership, and cybersecurity teams is required. The position requires five years of relevant experience, a bachelor’s degree, ITIL v4 Foundation certification, and Public Trust or active Secret clearance.

Develop, deploy, and optimize scalable machine learning solutions, including predictive models, deep learning systems, data pipelines, and model-serving infrastructure. Monitor model performance, manage retraining and lifecycle processes, ensure quality and compliance, and support responsible AI practices. Collaborate with data scientists, engineers, product teams, and business stakeholders while researching emerging AI technologies and improving AI architectures.

Leads the architecture, development, deployment, and optimization of enterprise machine learning solutions. Responsibilities include designing scalable ML systems, developing predictive models, supporting MLOps and model lifecycle management, improving data quality and feature engineering, implementing governance and validation frameworks, and mentoring technical teams. The role also contributes to AI strategy, innovation initiatives, responsible AI practices, and organizational modernization.

Own the full machine learning lifecycle for search ranking and retrieval, including model training, deployment, serving, feature pipelines, evaluation frameworks, hybrid lexical-vector retrieval, large-scale embedding inference, query understanding, and permissions-aware multi-tenant search. Collaborate with infrastructure, AI, and backend teams to improve search relevance across ClickUp’s platform.

Design and productionize ML models and agentic systems for intraday financial alpha generation. Build data pipelines, experiment frameworks, and portfolio optimization methods. Collaborate with quants and engineers to move models from research to live trading environments.

Lead design, development, and deployment of large-scale production ML systems and platform strategy. Research and prototype ML and big-data technologies, integrate ML services across the org, mentor engineers and data scientists, and communicate complex ML solutions to technical and non-technical stakeholders.

Design, build, and deploy autonomous AI agents using LLMs and agent frameworks; integrate agents into e-commerce and supply chain systems; implement multi-agent orchestration, memory and tool integrations; fine-tune models and apply RL concepts; and build safety, monitoring, and MLOps pipelines.

Set the technical direction for machine learning at Payabli by maturing production risk models and launching new models across the payments lifecycle. Establish experimentation, monitoring, drift detection, benchmarking, retraining, and incident-response foundations. Translate payments challenges into modeling opportunities, connect model performance to business outcomes, influence the ML roadmap, and mentor engineers while partnering with product, engineering, and risk operations.