Top Remote Machine Learning Engineer Jobs in Denver & Boulder, CO

Develop and maintain production machine learning models, build scalable training and serving technologies, optimize real-time and batch ML pipelines, and monitor model performance and drift. The role involves deep neural networks, recommendation systems, automated retraining, ML research, engineering excellence, and communicating technical concepts to diverse audiences. Candidates need 6+ years of industry ML experience, strong coding skills, and experience deploying neural networks at scale.

Lead end-to-end LLM inference performance across serving systems, models, GPU hardware, and workloads. Define rigorous benchmarks, diagnose bottlenecks from scheduling through kernels and interconnects, optimize single- and multi-node deployments, and deliver production-ready runtimes and configurations. Collaborate with product and infrastructure teams, evaluate inference technologies, and implement runtime fixes. The role requires strong Python engineering, production experience with serving engines such as vLLM or SGLang, GPU profiling, and knowledge of modern inference optimization techniques.

Design, build, and support high-throughput, low-latency LLM inference and data pipelines; collaborate with data scientists to post-train and evaluate models; implement scalable, production-ready systems with strong testing, monitoring, and performance focus; mentor engineers and iterate on architecture, reliability, and user-facing AI applications.

Lead production-grade ML systems: build data pipelines, training and evaluation workflows, and scalable GPU inference. Fine-tune and adapt large models (LoRA, QLoRA, SFT, DPO, distillation), optimize deployments for latency/cost/reliability, and collaborate with product and engineering to ship robust, observable model-driven features.

Design, build, and operate large-scale ML systems across data, training, evaluation, inference, and deployment. Lead GPU-optimized training and inference pipelines, ensure reliability, performance, safety, and seamless integration into products. Own production deployments, monitoring, and cross-functional best practices to drive measurable model improvements and efficient research-to-production cycles.

Develop, implement, and deploy scalable machine learning models for healthcare solutions. Collaborate cross-functionally to integrate models, analyze data to improve performance, ensure data quality, and stay current with ML advancements to support patient care and operational efficiency.

Senior AI/ML Engineer responsible for translating federal supply chain and logistics problems into analytical solutions, developing forecasting, classification, and NLP models, and deploying them into production. The role owns model development, data pipelines, monitoring, retraining, drift detection, validation, documentation, and stakeholder communication. Work includes operating within government-controlled environments and meeting federal bias evaluation and documentation requirements.

Design, build, and deploy autonomous AI agents using LLMs and agent frameworks; integrate agents into e-commerce and supply chain systems; implement multi-agent orchestration, memory and tool integrations; fine-tune models and apply RL concepts; and build safety, monitoring, and MLOps pipelines.

Design, develop, and implement AI/ML models; analyze large datasets; integrate AI solutions into existing systems; apply MavLink for autonomous systems; collaborate across teams and improve ML development processes.

Build and deploy production AI/ML and GenAI systems across the full model lifecycle. Develop RAG pipelines, LLM integrations, data pipelines, labeling workflows, evaluation frameworks, and MLOps infrastructure. Apply AI to manufacturing, computer vision, predictive maintenance, supply chain, forecasting, inventory, supplier risk, and logistics. Collaborate with engineering, manufacturing, and operations teams to deliver measurable business outcomes.

Lead the design, development, deployment, and operation of production AI and ML systems. Build high-throughput Python services and Databricks pipelines, support traditional ML and LLM applications, establish testing and deployment standards, and develop monitoring for quality, reliability, latency, throughput, and cost. Partner with product, research, and responsible AI teams on governance and release criteria. Provide architectural leadership, conduct code reviews, mentor engineers, and resolve complex technical dependencies.

Build and deploy production AI/ML features across the model lifecycle, including GenAI systems, RAG pipelines, data pipelines, evaluation infrastructure, and MLOps. Apply machine learning to manufacturing, supply chain, computer vision, predictive maintenance, forecasting, inventory, and logistics problems. Collaborate with engineering, manufacturing, and operations teams to deliver measurable outcomes.

Designs, deploys, and scales production AI agents and agentic workflows within enterprise Java and Spring applications. Establishes evaluation, monitoring, guardrail, safety, testing, observability, deployment, and operational standards for LLM systems. Leads architectural decisions across AI services and microservices, productionizes models, evaluates emerging technologies, mentors engineers, and influences technical strategy across teams.

Build and deploy production AI agents, agentic workflows, and ML-enabled enterprise features within Java/Spring microservices. Implement evaluation, monitoring, guardrails, safety, testing, and observability for LLM applications. Collaborate with AI scientists, engineers, product managers, and technical specialists to productionize models, integrate RAG and tool calling, prototype solutions, and improve AI capabilities. The role also involves design reviews, agile planning, software quality ownership, and staying current with emerging AI technologies.

Build production machine learning benchmarks and evaluation systems for foundation models. Own backend infrastructure including data pipelines, execution environments, storage, and orchestration, as well as sandboxed environments for agentic evaluations. Partner with researchers, enterprise customers, and company leadership to scope and deliver technical solutions. Identify scalable evaluation patterns, communicate clearly, and operate effectively in an ambiguous, high-ownership startup environment.

Lead the design, development, deployment, and monitoring of production AI/ML applications for dairy-farm intelligence. Responsibilities include data wrangling, feature engineering, model selection, experimentation, MLOps, agent evaluation, observability, fine-tuning, AI governance, and integration with cloud infrastructure. The role also drives AI adoption, establishes engineering practices, collaborates cross-functionally, and may build React and TypeScript user experiences.

Lead the design, development, deployment, and monitoring of production AI/ML applications for dairy farm intelligence. Responsibilities include data wrangling, feature engineering, model selection, experimentation, MLOps, agent evaluation, observability, fine-tuning, AI governance, and adoption enablement. The role also involves collaborating on React and TypeScript user experiences, translating ambiguous requirements into scalable systems, and communicating technical tradeoffs across product, engineering, and dairy science teams.

Develop and maintain open-source Python frameworks and ML developer tools, architect scalable libraries, grow early-stage projects, build real-time streaming capabilities, integrate modern frontend technologies, and collaborate with open-source contributors and the broader developer community.

The Staff Machine Learning Engineer will design and build scalable ML systems, mentor engineers, and drive AI strategy at SailPoint, focusing on AI-powered identity security solutions.

Lead DigitalOcean’s AI security strategy, governance framework, and multi-year roadmap. Secure AI/ML systems across data ingestion, training, model serving, RAG, agents, and monitoring. Conduct threat modeling, adversarial testing, AI red teaming, and security reviews; develop guardrails and automation with engineering teams. Advise executives and the board on AI risk, define organizational controls, and guide responses to emerging threats including prompt injection, model supply-chain risks, and AI-enabled social engineering.

Lead technical direction for high-impact machine learning initiatives, from research and experimentation through production deployment. Build and fine-tune LLMs, document understanding systems, model-serving infrastructure, evaluation frameworks, and data feedback loops. Establish standards for model quality, calibration, reproducibility, and responsible deployment while mentoring ML engineers and influencing organizational roadmaps. The role requires hands-on software and ML engineering expertise, production-scale model development, and strong statistical judgment.

Own the research-to-production pipeline: harden training/evaluation workflows, build packaging/deployment tooling, design release gates, optimize inference and serving for latency/throughput, establish benchmarking and validation, and instrument feedback from production to accelerate research iteration.

Develops and productionizes deep learning and machine learning perception models for robotics and recycling sortation. Responsibilities include experimenting with neural network architectures, designing computer vision solutions, conducting statistical experiments, deploying successful models, collaborating with data, modeling, and cloud infrastructure teams, and improving ML infrastructure.

Develop, train, evaluate, and deploy machine learning models and AI-powered applications. Responsibilities include data preprocessing, feature engineering, deep learning development, cloud-based model deployment, and collaboration with data engineers, MLOps teams, and business stakeholders. The role also requires applying strong analytical and research skills while staying current with advances in artificial intelligence.

Build and operate production machine learning training systems on Amazon SageMaker using AWS Trainium. The role focuses on optimizing PyTorch code for Trainium hardware, understanding NeuronCore compilation, diagnosing device-level issues, tuning distributed training for cost and throughput, and delivering production pipelines. The engineer will collaborate directly with client and internal teams in a forward-deployed engineering environment.