Top Python Jobs in Denver & Boulder, CO

Senior level
Artificial Intelligence • Machine Learning • Natural Language Processing • Software • Generative AI
Develop and maintain open-source Python frameworks and ML developer tools, architect scalable libraries, grow early-stage projects, build real-time streaming capabilities, integrate modern frontend technologies, and collaborate with open-source contributors and the broader developer community.
Top Skills: JavaScriptPythonReactSvelteTypescriptWebrtcWebsockets
2 Months AgoSaved
Remote
Colorado
100K-130K Annually
Senior level
100K-130K Annually
Senior level
Healthtech • Pharmaceutical • Hospitality
Build and maintain scalable backend applications, serverless functions, microservices, data workflows, ETL pipelines, and cloud-native architectures using Python and AWS. Manage databases, APIs, batch jobs, and real-time integrations while optimizing performance, scalability, security, compliance, and cost. Collaborate with product, engineering, analytics, and data teams; contribute to architecture, CI/CD, infrastructure automation, development standards, and technical mentorship. Healthcare claims data experience is required.
Top Skills: Amazon Api GatewayAmazon AuroraAmazon KinesisAmazon RdsAmazon RedshiftAmazon S3AWSAws GlueAws LambdaAws Step FunctionsCi/CdData LakesData WarehousesDevOpsETLHipaaHl7Infrastructure As CodeMicroservicesMySQLPostgresPythonServerless ComputingSQLStored Procedures
Reposted 2 Months AgoSaved
In-Office
Colorado
102K-157K Annually
Senior level
102K-157K Annually
Senior level
Hardware • Database • Defense
Develop, prototype, integrate, and test Python-based software for missile warning/tracking missions. Contribute to containerization, testing, deployment, and provide technical guidance to team members while supporting DoD programs and maintaining high software engineering standards.
Top Skills: DockerGitlab-Ci/CdGrpcJenkinsKafkaMicroservicesPostgisProtobufPythonRedisRest ApisSQLZmq
2 Months AgoSaved
Remote
Colorado
200K-225K Annually
Senior level
200K-225K Annually
Senior level
Artificial Intelligence • Computer Vision • Machine Learning • Analytics
Develop open source SDKs, enterprise APIs, UIs, and backend systems supporting large-scale computer vision datasets. Build scalable, maintainable, performant, and well-tested software for unstructured data and AI workflows. Contribute to enterprise deployments across customer clouds and on-premises environments, while improving tooling, automation, engineering practices, and open source community initiatives in a remote-first team.
Top Skills: DocumentdbElasticsearchMongoDBPythonTypescript
Reposted 2 Months AgoSaved
Remote
Colorado
Senior level
Senior level
Artificial Intelligence • Information Technology • Professional Services • Software
The Senior Full Stack Developer will design, develop, test, and debug software solutions, collaborating with teams and optimizing applications. Responsibilities include user interaction design, back-end functionality, and ensuring software scalability and security.
Top Skills: CSSDjangoDockerFastapiFlaskGitGnu/LinuxHTMLJavaScriptMongoDBMySQLNode.jsOraclePostgresPythonReactSvnVue
Reposted 2 Months AgoSaved
In-Office or Remote
Colorado
135K-155K Annually
Senior level
135K-155K Annually
Senior level
Machine Learning • Other
The Backend Software Engineer will develop and maintain backend systems for data processing related to coffee farming, utilizing Python and PostgreSQL. Responsibilities include feature development, problem-solving, and adapting systems to regulatory changes while ensuring system resilience.
Top Skills: AWSCi/CdDockerPostgresPostgresql/PostgisPythonTerraform
Reposted 2 Months AgoSaved
In-Office or Remote
Colorado
2K-2K Annually
Mid level
2K-2K Annually
Mid level
Cloud • Software
As a Python and Kubernetes Software Engineer, you will develop data analytics solutions using open source tools, collaborating with a distributed team.
Top Skills: AirflowApache SupersetApache TrinoAWSAzureClickhouseDbtDockerDvcFeastGCPKubernetesLxdMlflowPythonTemporal
Reposted 2 Months AgoSaved
In-Office or Remote
Colorado
Senior level
Senior level
Cloud • Software
The Python Engineer will write maintainable Python software, lead technical initiatives, collaborate globally, and contribute to community engagement at Canonical.
Top Skills: CC++DockerGoKubernetesLinuxNoSQLPythonRustSQL
Reposted 2 Months AgoSaved
Remote
Colorado
100K-130K Annually
Mid level
100K-130K Annually
Mid level
Digital Media
The Senior Software Engineer will develop features, maintain quality, review code, and collaborate on product design for the EnrollWise platform, focusing on back-end and some front-end work.
Top Skills: AWSDjangoJavaScriptPython
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Reposted 2 Months AgoSaved
In-Office or Remote
Colorado
Senior level
Senior level
Digital Media
Develop and enhance features for EnrollWise, contribute to a scalable software architecture, review code, collaborate on design and technical feasibility, and maintain software quality.
Top Skills: ApolloAWSDjangoDjango OrmGraphQLNextjsPythonReact
2 Months AgoSaved
Remote
Colorado
Senior level
Senior level
Information Technology • Software • Consulting
Build and maintain full-stack wealth management platform features using Python and Angular or React. Design service-oriented architectures and REST/SOAP APIs, work with relational databases and ORMs, contribute to AWS or Azure cloud architecture, and deploy using container technologies. Collaborate in Agile/Scrum ceremonies, participate in code reviews and demos, and work independently with distributed teams.
Top Skills: AngularAWSAzureConfluenceDjangoDockerEcsFlaskJavaScriptJIRAJSONKubernetesMySQLOracleOrmPostgresPythonReactRestSoapSQLSQL Server
Reposted 2 Months AgoSaved
In-Office or Remote
Colorado
36K-126K Annually
Entry level
36K-126K Annually
Entry level
Agency • Information Technology
Develop and maintain scalable Python backend applications and RESTful APIs. Optimize performance, design and manage SQL/NoSQL schemas, implement security/authentication, write tests, automate CI/CD tasks, and collaborate with front-end, product, and QA teams.
Top Skills: BitbucketCSS3DjangoDjango OrmFastapiFlaskGitGitHTML5JavaScriptMongoDBMySQLPostgresPytestPythonRedisSqlalchemyUnittest
3 Months AgoSaved
Remote
Colorado
Mid level
Mid level
Software
Build and own backend surfaces for Plane: APIs, data models, migrations, real-time sync (CDC/event streams), caching, and query performance. Instrument, monitor, and debug production incidents; collaborate with product and frontend teams across locations.
Top Skills: AsyncioAWSDatadogDjangoFastapiFigmaGitGoKafkaKubernetesNode.jsPostgresPythonRabbitMQRancherRedisSentrySlackSQL
3 Months AgoSaved
Remote or Hybrid
Colorado
165K-210K Annually
Senior level
165K-210K Annually
Senior level
eCommerce • Information Technology • Machine Learning • Marketing Tech • Database • Analytics • Big Data Analytics
Design and implement scalable backend and distributed systems for a marketing intelligence platform. Build near-real-time ingestion and processing, scale an incrementality/experimentation product, integrate AI-powered workflows, improve data ingestion/exports and connection-state systems, and contribute frontend components to deliver end-to-end product experiences.
Top Skills: AIAPIsData ProcessingDistributed SystemsMachine LearningMicroservicesPythonRbacReactReal-Time Data IngestionTypescript
Reposted 3 Months AgoSaved
Remote
Colorado
Expert/Leader
Expert/Leader
Artificial Intelligence • Information Technology • Machine Learning • Software • Virtual Reality • Analytics
Nagarro seeks an Associate Principal Engineer with extensive IT experience in Python to drive strategic value and innovation in product engineering.
Top Skills: Python
Reposted 3 Months AgoSaved
In-Office
Colorado
60K-60K Annually
Senior level
60K-60K Annually
Senior level
Artificial Intelligence • Information Technology • Software • Consulting
Develop high-performance, highly available server-side systems in Python using Django/Flask. Build REST/SOAP/JSON APIs, work with messaging systems (RabbitMQ/ActiveMQ, Kafka preferred), Cassandra and Zookeeper. Apply distributed systems, algorithms, advanced data structures, networking and OS knowledge. Participate in Agile/Scrum processes. Bachelor's degree required.
Top Skills: ActivemqApache KafkaApache ZookeeperCassandraDjangoFlaskJSONNoSQLPythonRabbitMQRestSoap
Reposted 3 Months AgoSaved
Remote
Colorado
125K-200K Annually
Senior level
125K-200K Annually
Senior level
Software • Cybersecurity
The Forward Deployed Engineer will serve as a technical bridge between clients and engineering teams, writing custom code and integrations, while ensuring customer success with Socket's security platform through strong relationships and expert technical guidance.
Top Skills: Automation ScriptsCi/CdDevOpsPythonSastWebhook Implementations
4 Months AgoSaved
In-Office or Remote
Colorado
Entry level
Entry level
Gaming • Mobile • Travel
Build and maintain Python tools for web scraping, automation, integrations (Airbnb, marketplaces), ad automation, chatbots (Chatwoot), workflow automation (Spiffworkflow), automated tests, and data analysis.
Top Skills: BpmnChatwootClaude CodeCursorDjangoFlaskGitGitlabLinuxNoSQLPytestPythonRequestsSeleniumSpiffworkflowSQLUnittestVs Code Copilot
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