Top Senior Systems Engineer Jobs in Denver & Boulder, CO

Build and improve the Enterprise AI operating model through AI-enabled processes, operational reporting, knowledge management, stakeholder forums, intake governance, and asset registry oversight. The role translates complex program information into executive narratives, coordinates decision-making, enables cross-functional alignment, and continuously improves planning, prioritization, governance, communication, and execution mechanisms.

Leads systems engineering for satellite ground systems supporting a national missile tracking program. Responsibilities include requirements derivation and traceability, system architecture, concept of operations, integration, verification and validation, milestone reviews, technical risk management, and performance tracking. The role coordinates cross-functional teams, government stakeholders, and subject matter experts while architecting command-and-control, mission operations, telemetry, data processing, and network infrastructure solutions for ground-to-space mission support.

Lead project-level systems engineering for a solar physics space mission from concept through operational delivery. Provide technical authority, mission architecture, requirements management, design trade studies, risk mitigation, technical governance, and hardware lifecycle oversight. Coordinate multidisciplinary engineering teams, the Principal Investigator, science teams, executives, and NASA stakeholders. Develop CONOPS, lead technical reviews and readiness boards, deliver executive briefings, establish systems engineering standards, and mentor engineers.

Leads end-to-end systems engineering for a solar physics space mission, overseeing mission concepts, requirements, CONOPS, design trades, risk, verification, hardware execution, operational delivery, and technical governance. Serves as the primary technical liaison among engineering teams, the Principal Investigator, science teams, executives, NASA stakeholders, and government officials. Mentors engineers, establishes systems engineering standards, and provides strategic technical recommendations.

Leads electrical power and distribution subsystem engineering for spacecraft programs. Responsibilities include spacecraft power system development, battery and solar array engineering, payload interface development, power sizing and analysis, component procurement oversight, power architecture advancement, IR&D, and technical representation across mission programs. Requires extensive spacecraft electrical power experience and collaboration across engineering, program, and subcontractor teams.

Leads spacecraft electrical power system engineering across national defense and civil space programs. Responsibilities include power subsystem development, battery and solar array ownership, payload interface design, power sizing, proposal support, component procurement oversight, architecture advancement, IR&D, and mission-level technical representation. The role requires collaboration across teams, analysis using power simulation tools, and development of space-qualified hardware.

Designs, integrates, tests, and supports spacecraft and ground systems. Responsibilities include analyzing subsystem performance, developing spacecraft commands and telemetry, managing flight software configurations, maintaining command and telemetry tools, and resolving anomalies. The role collaborates with cross-functional engineering teams in an on-site office, laboratory, production, or cleanroom environment.

Leads space vehicle architecture for new business pursuits and mission areas, supporting spacecraft bus and systems solutions, capture strategy, RFIs, proposals, design reviews, and technical baselines. Interfaces with customers, partners, and multidisciplinary teams; develops engineering documentation, assesses technical risks, supports IRAD initiatives, and coaches systems engineers. Requires extensive systems engineering leadership, customer engagement, presentation skills, and an active Top Secret/SCI clearance.

Develop and maintain electrical special test equipment systems for payloads and spacecraft. Lead requirements, system design, software development, verification, documentation, troubleshooting, production support, cost estimation, procurement tracking, and post-delivery customer support. Manage classified-program information assurance and rack-ingress processes, including software patching and cleansing. Support LabVIEW and Ruby codebases, collaborate across engineering and production teams, and mentor junior engineers.

Lead complex enterprise technical engagements for iPaaS and hybrid integration solutions. Design connectivity architectures spanning application integration, EDI, MFT, event streams, hybrid and multi-cloud environments. Conduct consultative discovery, lead proof-of-concepts, present to executives, and coordinate technical win teams for RFI/RFP responses. Advise customers on legacy modernization, API management, microservices orchestration, and secure AI-driven integrations.

Build and validate data-center performance and power models for SSD and DRAM products. Develop modeling, simulation, and analysis tools using Python, C, or C++; test server platforms; measure throughput, latency, bandwidth, endurance, and power; analyze AI and data-intensive workloads; and communicate technical recommendations to architects, product engineers, and system designers.

Develop and maintain population-scale NLP and LLM pipelines that extract and validate suicide-related phenotypes from VA clinical notes. Prepare analysis-ready datasets for statistical genetics research, ensure reproducibility and compliance with PHI/PII security requirements, troubleshoot performance and data quality issues, and provide technical documentation and milestone updates to the research team.

Provides senior systems engineering support for the GRIFFON ground integration and systems-of-systems integration contract. Responsibilities include defining interfaces, decomposing and tracing requirements in DOORS, developing system architectures, conducting trade studies, planning verification and integration campaigns, assessing technical baseline changes, and creating requirements sell-off plans. The role also supports digital engineering, MBSE, digital twins, Agile development, and risk reduction for system-level verification activities.

Architects and operates enterprise endpoint platforms across Windows and macOS, including device provisioning, application delivery, patching, compliance, security, automation, and lifecycle management. The role leads complex technical projects, resolves escalated endpoint issues, partners with security and support teams, evaluates technologies, improves employee experience, documents systems, and mentors engineers.

Develops, integrates, tests, maintains, and supports Java-based software systems and mathematical algorithms for Boeing’s C2BMC missile defense applications. Responsibilities include software architecture, requirements decomposition, interface development, design documentation, coding, debugging, performance optimization, agile execution, integration and testing, operational support, and technical issue resolution. The role collaborates with systems engineering, integration and test teams, and industry partners while supporting full software lifecycle activities for ballistic missile defense systems.

Provide senior systems engineering, integration, interoperability, sustainment, testing, troubleshooting, and technical advisory support for MILSATCOM and Protected MILSATCOM systems. Analyze architectures, cryptographic requirements, interfaces, modifications, and operational impacts; support AEHF capabilities and allied architectures; conduct technical assessments and site surveys; maintain engineering documentation; and assist operators and maintainers at CONUS and OCONUS locations.

Leads the design, development, integration, and validation of real-time space vehicle simulators in hardware-in-the-loop and software-only environments. Defines requirements, architectures, interfaces, and use cases; guides technical decisions and simulator quality; performs the full software lifecycle; and deploys containerized simulation components. The role requires systems engineering leadership, software development expertise, real-time operating systems knowledge, and experience with model-based simulation, control theory, and formal development practices.

Designs, implements, administers, and supports critical Linux infrastructure and high-transaction systems. Responsibilities include troubleshooting, root-cause remediation, security and compliance, infrastructure design, automation, monitoring, virtualization, application platform support, documentation, incident response, and technical leadership. The role also mentors engineers and collaborates with security, networking, storage, application, vendor, and customer teams.

Lead complex systems initiatives for Cloudflare Browser Isolation across Chromium, distributed services, and remote browsing infrastructure. Design and implement C++, Rust, Go, and TypeScript systems; investigate cross-layer performance and reliability issues; improve observability, capacity, rollout safety, and resilience. The role includes architectural decision-making, technical leadership, mentoring, cross-team coordination, incident response, and production on-call participation.

Supports Lunar Human Landing System development through systems engineering and engineering operations. Develops requirements, safety, verification, and validation baselines; coordinates cross-functional technical needs; plans major reviews and milestones; investigates anomalies; improves operational processes; and tracks technical progress, risks, decisions, and deliverables using tool-driven workflows.

Supports EADGE-T integrated air and missile defense modernization through systems engineering activities. Decomposes high-level requirements, manages requirements in DOORS Next, participates in design reviews, conducts trade studies and alternatives analyses, performs requirements verification, and contributes to system architecture using MBSE tools such as SysML and Cameo within an Agile Scrum environment.

Provides systems engineering and integration support for U.S. Space Force PNT capabilities. Responsibilities include requirements integration, architecture, baseline and lifecycle management, risk analysis, interface control, acquisition, testing, operations, sustainment, and technical documentation. The role collaborates with government personnel, contractors, and Integrated Product Teams to assess enterprise changes and support space and ground system capabilities.

Design, build, and operate the Linux-based edge appliance runtime and distributed control plane. Implement secure networking dataplanes (IPsec, MASQUE, eBPF), reliable fleet control and remote lifecycle management, telemetry and diagnostics, and drive product-focused technical leadership from architecture through rollout and incident response.

Develops Model Based Systems Engineering products and documentation for Space Force remote sensing and missile warning systems. Responsibilities include defining system and subsystem requirements, use cases, architectures, interfaces, software traceability, and test cases. Supports technical reviews, backlog grooming, engineering baseline alignment, and coordination with software, test, and engineering teams on large-scale national defense programs.

Provide Model Based Systems Engineering products and documentation for space-ground systems, including requirements, use cases, architectures, interfaces, traceability, and test cases. Support technical reviews, backlog grooming, engineering baselines, and coordination among systems, software, and test engineers. The role supports the Space Force FORGE Enterprise OPIR Solution program and requires on-site work in Boulder, Colorado.