Top Senior Systems Engineer Jobs in Denver & Boulder, CO

Lead design and implementation of data architecture and scalable storage solutions, drive AI/GenAI thought leadership, oversee data governance and security, translate business requirements into technical plans, implement FastAPI endpoints, enhance LLMs through prompt engineering, and manage cross-functional teams to deliver advanced data and AI solutions.

Develop and optimize AI and machine learning algorithms, models, and scalable Python systems. Transform raw data into actionable insights, apply machine learning libraries and NLP techniques, improve data quality, and deliver automation solutions for clients. The role also involves complex data analysis, stakeholder collaboration, client relationship management, and navigating ambiguous business challenges.

Supports USSF space test and training capabilities through feasibility studies, mission engineering, CONOPS, requirements management, systems integration, verification, validation, acquisition, fielding, and sustainment. Collaborates with government, engineering, acquisition, and program stakeholders while aligning technical efforts with PPBE activities. Requires extensive DoD systems engineering experience, space systems knowledge, Cameo and SysML expertise, an active Top Secret clearance with SCI eligibility, and up to 25% travel.

Lead architecture and implementation of Cloudflare Tunnel systems (client and edge services). Design, code, test, monitor, and scale distributed, secure microservices. Mentor peers, drive roadmap, debug production issues, and collaborate with security, SRE, network engineering, and product teams.

Develops and leads system safety, mission assurance, reliability, and risk-management strategies for rocket motor and propulsion systems. Responsibilities include safety board coordination, hazard classification, risk registers, system-level failure assessments, lifecycle planning, flight-test safety, reliability assessments, and failure investigations. Collaborates with design, testing, manufacturing, mission operations, and program teams, while interfacing with Department of Defense safety review boards.

The role involves designing and leading the development of focal plane subsystems for space applications, overseeing project execution, and collaborating with technical teams.

Leads mission architecture across the systems engineering lifecycle, from concept development and trade studies through implementation and launch. Defines architectures, CONOPS, requirements, and technology roadmaps using MBSE. Supports proposals, business capture, IRAD, customer relationships, and multidisciplinary technical teams across ground, air, and space domains. Mentors systems engineers and communicates complex technical strategies to senior leaders and government or industry customers.

Leads mission architecture from concept through implementation and launch across ground, air, and space domains. Defines system architectures, CONOPS, requirements, and trade studies; applies MBSE and modeling practices; supports proposals, capture, IRAD, and technology roadmaps. Coordinates multidisciplinary teams, mentors systems engineers, and builds customer relationships. Requires active Secret clearance with ability to obtain Top Secret/SCI and five-day on-site work.

Leads mission architecture across the full systems engineering lifecycle, from concept development and trade studies through implementation and launch. Defines CONOPS, system requirements, MBSE models, and technical roadmaps across ground, air, and space domains. Supports proposals, capture efforts, IRAD, customer relationships, and multidisciplinary technical teams. Mentors systems engineers and communicates complex architectures to senior leadership and government or industry customers.

Leads mission architecture across space and defense programs from concept development through implementation and launch. Performs architecture development, trade studies, CONOPS definition, and MBSE modeling while translating customer needs into technical solutions. Supports proposals, capture activities, IRAD, and technology roadmaps; leads multidisciplinary teams, develops customer relationships, and mentors systems engineers. The role requires expertise across ground, air, and space domains and regular onsite work.

Leads mission architecture from concept through implementation and launch across ground, air, and space domains. Defines system architectures, CONOPS, requirements, and trade studies using MBSE. Supports proposals, business capture, IRAD, customer relationships, and technology roadmaps. Leads and mentors multidisciplinary engineering teams while communicating complex technical concepts to senior leaders and government or industry customers.

Leads mission architecture across space and defense programs from concept development through implementation and launch. Defines system architectures, CONOPS, requirements, and technical trade studies; applies MBSE; supports proposals, capture, IRAD, and technology roadmaps; develops customer relationships; and leads, mentors, and coordinates multidisciplinary engineering teams.

Design, build, and operate Cloudflare’s globally distributed cache and reverse-proxy data plane. Responsibilities include improving Pingora-based asynchronous systems, cache performance and correctness, purge and Tiered Cache services, APIs, observability, reliability, and production operations. The role owns features end to end, including design, implementation, testing, staged rollouts, incident response, and cross-team collaboration.

Build and operate secure, scalable multi-cloud infrastructure across AWS, GCP, and networking platforms. Develop self-service tooling, infrastructure-as-code defaults, cloud guardrails, and standardized platform patterns. Lead cross-team infrastructure initiatives, technical investigations, and operational improvements while partnering with security, compute, routing, and other infrastructure teams.

Performs cybersecurity engineering, system security assessments, vulnerability scanning, RMF compliance, secure configuration, troubleshooting, monitoring, and security documentation for a defense satellite communications and missile warning system. The role supports NIST, DoD, DISA, and customer cybersecurity requirements, develops authorization packages, collaborates with cross-functional teams, and uses endpoint protection, SIEM, and vulnerability management tools. An active Secret clearance and IAT Level II certification are required.

Designs and integrates secure information systems, cloud, and defense architectures; leads federal NIST RMF and ATO processes; implements security controls; performs vulnerability, threat, and risk assessments; advises engineering and program teams; and manages continuous monitoring, compliance, audit, and patch-management activities.

Leads the architecture, requirements, design, integration, verification, and operation of spacecraft TT&C communications for Blue Origin’s Sunrise satellite constellation. Owns RF link budgets, cascade analysis, CONOPS, interfaces, trade studies, testing, documentation, and risk mitigation. Provides technical direction for RF/microwave hardware, supports spacecraft commissioning and on-orbit operations, and leads and mentors the RF communications engineering team.

Leads integration and technical oversight of BE-7 propulsion hardware across lunar landers. Responsibilities include managing requirements, interface documents, performance parameters, risks, verification and validation, schedules, issue resolution, and NASA coordination. The role evaluates engine designs against program requirements and supports certification of human-rated lunar delivery systems.

Leads engineering and operational sustainment for a theater-wide air surveillance and communications system. Manages technical baselines, network design, maintenance, compliance, configuration management, fault isolation, performance monitoring, systems integration, modernization, and enterprise architecture evaluations. Supports hardware, software, and network sustainment, briefs military leadership, and assists field service representatives across Europe. Requires an engineering degree, 8+ years of relevant experience, operational air defense systems expertise, and an active Secret clearance.

Supports protected satellite communications payload and network operations for AEHF and Milstar systems. Performs on-site anomaly analysis, root-cause investigations, corrective action, operational planning, test conduction, payload software upload support, resource reallocation, and constellation reconfiguration. Coordinates with factory experts and stakeholders, develops anomaly resolution procedures, prepares technical briefings and reports, and supports mission operations, including occasional off-hours recall and surge activities.

Maintains cybersecurity posture for defense space systems through access control, security configuration, RMF compliance, vulnerability and incident response, policy enforcement, configuration management, and cybersecurity documentation. Coordinates with ISSM, security authorities, and cybersecurity offices to address risks, exceptions, and system changes. Requires DoD/IC space acquisition experience, Top Secret/SCI clearance, Security+ certification, and up to 10% travel.

Develops and applies systems engineering processes for defense and aerospace software, remote sensing, and sensor data processing systems. Responsibilities include requirements derivation and traceability, architecture modeling, standards and interface analysis, software conformance testing, certification documentation, issue resolution, and mentoring. The role requires onsite work in Boulder, U.S. citizenship, and the ability to obtain and maintain a DoD Secret clearance.

Own the reliability, availability, performance, observability, and security of Ophelia’s GCP telehealth platform. Define SLOs, improve monitoring and incident response, expand Terraform infrastructure, strengthen CI/CD, manage disaster recovery, and address latency and Cloud Run performance. Lead on-call maturity, HIPAA/SOC 2 infrastructure controls, and reliability education for engineers. Use AI-assisted tools for automation and incident triage while partnering with technical and non-technical stakeholders.

Leads systems engineering and SEIT execution for Red LAN sustainment, technical baseline management, software integration, interface engineering, requirements analysis, configuration-controlled changes, testing, and verification. Manages technical project risks, develops system and lower-level requirements, supports design reviews, prepares verification and acceptance procedures, and delivers technical documentation and briefings. Requires a bachelor's degree, 10–12 years of related experience, active TS/SCI clearance, and U.S. citizenship.

Leads spacecraft systems engineering across the product lifecycle, including requirements decomposition and traceability, system architecture, interface management, fault management, verification and validation, integration, launch support, and on-orbit operations. Collaborates with multidisciplinary engineering and program teams, manages technical risks and configuration baselines, supports reviews and mission readiness, and mentors junior engineers while driving systems engineering process improvements.