Top Remote Staff Software Engineer Jobs in Denver & Boulder, CO

As a Staff Software Engineer, you will lead technical initiatives for the Core Platform team, focusing on infrastructure and security systems to enhance developer productivity and reliability.

Lead the Payments Team by architecting and maintaining high-performance backend services, addressing complex engineering challenges, and mentoring engineering talent.

As a Senior Staff Engineer, you will lead technical vision and architectural direction for Payments Compliance, ensuring scalable and cohesive compliance systems while partnering with cross-functional teams to navigate regulatory requirements.

The Staff Software Engineer will lead AI integration into software design, develop scalable systems, and mentor other engineers while improving best practices.

The role involves leading the architecture and implementation of hypervisor features, mentoring engineers, and driving technical vision for Lynx's Mosaic platform.

As a Staff Software Engineer, you'll lead the development of AI-driven automations, improving data integration and platform capabilities for cybersecurity teams with over 8 years of experience in complex backend applications and distributed systems.

Lead architecture and delivery of integration domains for an AI-driven SecOps platform. Own roadmaps, design microservice integrations (REST, GraphQL, streaming, LLM APIs), mentor engineers, set technical direction, and champion AI tooling to accelerate development, automation, and reliability.

Own and drive architecture for a major clearing-house domain: backend systems in Go on GCP, data pipelines that ingest and deduplicate unstructured vulnerability reports, customer onboarding and entitlement workflows, enforce observability and production readiness, set engineering standards, and collaborate on interfaces and roadmap planning.

Build and maintain electricity cost modeling REST APIs and DBT data pipelines, translate SME requirements into designs, participate in technical reviews, improve engineering processes, and collaborate across remote squads to deliver energy analytics and battery performance simulations.

Build and maintain electricity cost modeling REST APIs and DBT-driven data pipelines. Translate SME requirements into engineering designs, participate in design reviews, improve engineering practices, and deliver scalable analytics and battery performance simulations to inform DER ROI.

Lead architecture and build platform services for GoDaddy's Internal Developer Platform used by 1,000+ engineers. Design high-scale APIs, infrastructure orchestration, and AI-powered developer tooling. Partner with infrastructure, security, and platform teams. Own production systems (performance, reliability, on-call) and drive technical direction to improve developer productivity across APIs, CLI, and UI.

Design, develop, and maintain production-scale APIs and distributed systems in Golang on Kubernetes. Provide technical leadership, participate in design reviews, write tests and documentation, collaborate cross-functionally, improve developer workflows including AI-assisted tooling, and support on-call operations.

The Security Software Engineer will design and implement security controls for MongoDB Atlas, collaborating across engineering teams and ensuring adherence to high security standards.

Lead design and delivery of enhancements to a next-generation AI agent platform. Own large features and infrastructure, mentor engineers, set technical standards, drive cross-team initiatives, improve reliability and SLOs, and influence product and process decisions to scale systems supporting millions of interactions.

The Staff Software Engineer on the AUE team is responsible for designing and maintaining offensive cybersecurity services, mentoring team members, managing projects, ensuring code quality, and driving technical direction within a collaborative environment.

Build and maintain complex customer-facing features, support other engineers, and take ownership of technical decisions while collaborating with Product and Design teams.

The Staff Software Engineer will focus on quality-driven engineering, automated testing, CI/CD pipelines, AI integration, and mentoring junior engineers while collaborating remotely.

The role involves architecting scalable backend systems and data pipelines, providing technical leadership, and ensuring best practices in software development.

The Staff AI Engineer will design and build AI Assistants that automate workflows, integrate enterprise tools, and ensure systems are production-grade and secure. Responsibilities include developing APIs, enhancing assistant quality, collaborating with teams, and evaluating new AI models and tools.

Technical leader for the Planning and Recruiting team responsible for designing and scaling backend services for clinical trial matching, patient workflows, and provider integrations. Primarily backend-focused (Java/Kotlin) while contributing to frontend (React/TypeScript). Define architecture, APIs, observability, CI/CD, and production operations. Partner with product and design, lead cross-team initiatives, and mentor engineers to deliver reliable, scalable systems that improve clinical trial access.

As a Staff Software Engineer in Infrastructure, you will lead a team in building high-performance, distributed systems, guide project direction, mentor engineers, and improve data ingestion architecture.

Lead frontend architecture and technical direction for shared UI systems and design system. Build, maintain, and document reusable component libraries; collaborate with UX, product, and engineering. Champion accessibility, testing, performance, and design-to-code workflows. Mentor engineers, review contributions, and deliver major UI initiatives end-to-end while balancing technical debt and product needs.

Lead frontend architecture and product development for member-facing web and mobile apps. Build high-performance, accessible React/React Native UIs, own end-to-end features including APIs and backend services, mentor engineers, drive design system and frontend standards, and collaborate with Product, Design, Clinical, and Data teams to deliver scalable, user-centered health experiences.

Lead design and delivery of customer-facing data product applications, building full-stack experiences (frontend, backend, APIs) using TypeScript, React, Node.js, and Python. Partner with Product and data teams to convert analytics and prototypes into production-grade workflows, establish software engineering best practices, mentor engineers, and prioritize customer value through testing, observability, and operational ownership.

Lead end-to-end engineering for an AI-driven biomanufacturing platform: design and deploy LLM-powered agents and RAG systems, build full-stack React/Node.js/MongoDB platform and document intelligence pipelines, evolve AWS infra for GxP/Part11/SOC2 compliance, implement CI/CD, observability, and work with customers to integrate with LIMS/ERP/QMS.