Top Remote Staff Software Engineer Jobs in Denver & Boulder, CO

The Staff Engineer will lead the Systems team, design scalable cloud infrastructure, optimize data pipelines, and ensure platform reliability and security.

The Staff Software Engineer will design, build, and scale systems for virtual care, collaborating across teams, optimizing performance, and mentoring engineers.

The Senior Staff AI Software Engineer will architect an AI-native pharmacy benefits platform, focusing on software development, system design, and mentoring junior engineers.

The Sr Staff Software Engineer will build core banking experiences, craft user flows, robust APIs, and integrate with third-party software, requiring significant back-end development experience.

Develop and deploy AI agents, integrating them with external systems and optimizing performance in multi-agent environments. Collaborate with product managers to align agent capabilities with business needs, exploring technologies in Generative AI and LLM orchestration.

As a Technical Leader, you'll architect backend systems for clinical trial matching, ensuring reliable services while mentoring engineers across the stack.

The Staff Software Engineer leads technical development, designs features, collaborates across teams, and ensures software quality in an agile environment.

Lead the design and delivery of agentic-first capabilities in Nexus Repository. Responsible for architecture, mentoring, and defining engineering practices for secure software supply chains.

The Staff Software Engineer - Core Ingest will design and develop distributed data processing systems, ensuring high-volume, low-latency performance while managing petabytes of data. Responsibilities include improving algorithms and architecting solutions across multiple teams, with a strong focus on scalability and reliability.

Design and implement scalable backend systems for analytics, optimizing performance and resource efficiency while mentoring engineers and managing petabytes of data.

The Staff Software Engineer will lead technical initiatives, drive quality code, mentor engineers, and work on scalable systems in a high-impact team environment.

The Staff Software Engineer will lead technical excellence, design scalable systems, mentor engineers, and drive innovation in a cross-functional team.

Build and scale ML-optimized HPC infrastructure, manage Kubernetes-based GPU/TPU superclusters, optimize for AI/ML training, and mentor teams while innovating in ML infrastructure.

The Staff Software Engineer will enhance Scala systems, build a Rust framework, improve observability, and drive AI tool adoption while shaping developer standards.

As a Staff Software Engineer, you'll design and develop systems to integrate AI in healthcare payment processes, mentor engineers, and optimize workflows.

Design and build scalable web applications, collaborate on product direction, and implement complex systems using ML techniques, ensuring software quality.

The role involves designing and building scalable backend systems, contributing to enterprise software solutions, and managing complex API development.

Develop user-centric UI applications, collaborate with teams, and design scalable solutions while enhancing production-ready code as a Frontend Engineer.

The Staff Software Engineer will design and build scalable backend systems, lead projects, and contribute to enterprise software solutions, focusing on application architecture, API development, and ML techniques.

The job involves leading the design and development of core components for a data platform, implementing scalable data processing pipelines in Go, providing technical leadership, and participating in an on-call rotation.

As a Staff Software Engineer, you will develop and maintain back-end features, advocate best practices, mentor juniors, and engage in system design.

As a Staff Software Engineer, you'll lead the development of AI-driven automations, improving data integration and platform capabilities for cybersecurity teams with over 8 years of experience in complex backend applications and distributed systems.

As a Staff Software Engineer, you will lead technical initiatives for the Core Platform team, focusing on infrastructure and security systems to enhance developer productivity and reliability.

The Staff Software Engineer will lead AI integration into software design, develop scalable systems, and mentor other engineers while improving best practices.

Lead the development of high-performance software systems, mentor junior engineers, and contribute to technology strategy while ensuring scalable and maintainable solutions.