Top Remote Staff Software Engineer Jobs in Denver & Boulder, CO

The Security Software Engineer will design and implement security controls for MongoDB Atlas, collaborating across engineering teams and ensuring adherence to high security standards.

Lead design and delivery of enhancements to a next-generation AI agent platform. Own large features and infrastructure, mentor engineers, set technical standards, drive cross-team initiatives, improve reliability and SLOs, and influence product and process decisions to scale systems supporting millions of interactions.

The Staff Software Engineer on the AUE team is responsible for designing and maintaining offensive cybersecurity services, mentoring team members, managing projects, ensuring code quality, and driving technical direction within a collaborative environment.

Build and maintain complex customer-facing features, support other engineers, and take ownership of technical decisions while collaborating with Product and Design teams.

The Staff Software Engineer will focus on quality-driven engineering, automated testing, CI/CD pipelines, AI integration, and mentoring junior engineers while collaborating remotely.

The role involves architecting scalable backend systems and data pipelines, providing technical leadership, and ensuring best practices in software development.

The Staff AI Engineer will design and build AI Assistants that automate workflows, integrate enterprise tools, and ensure systems are production-grade and secure. Responsibilities include developing APIs, enhancing assistant quality, collaborating with teams, and evaluating new AI models and tools.

Technical leader for the Planning and Recruiting team responsible for designing and scaling backend services for clinical trial matching, patient workflows, and provider integrations. Primarily backend-focused (Java/Kotlin) while contributing to frontend (React/TypeScript). Define architecture, APIs, observability, CI/CD, and production operations. Partner with product and design, lead cross-team initiatives, and mentor engineers to deliver reliable, scalable systems that improve clinical trial access.

As a Staff Software Engineer in Infrastructure, you will lead a team in building high-performance, distributed systems, guide project direction, mentor engineers, and improve data ingestion architecture.

Lead frontend architecture and technical direction for shared UI systems and design system. Build, maintain, and document reusable component libraries; collaborate with UX, product, and engineering. Champion accessibility, testing, performance, and design-to-code workflows. Mentor engineers, review contributions, and deliver major UI initiatives end-to-end while balancing technical debt and product needs.

Lead frontend architecture and product development for member-facing web and mobile apps. Build high-performance, accessible React/React Native UIs, own end-to-end features including APIs and backend services, mentor engineers, drive design system and frontend standards, and collaborate with Product, Design, Clinical, and Data teams to deliver scalable, user-centered health experiences.

Lead design and delivery of customer-facing data product applications, building full-stack experiences (frontend, backend, APIs) using TypeScript, React, Node.js, and Python. Partner with Product and data teams to convert analytics and prototypes into production-grade workflows, establish software engineering best practices, mentor engineers, and prioritize customer value through testing, observability, and operational ownership.

Lead end-to-end engineering for an AI-driven biomanufacturing platform: design and deploy LLM-powered agents and RAG systems, build full-stack React/Node.js/MongoDB platform and document intelligence pipelines, evolve AWS infra for GxP/Part11/SOC2 compliance, implement CI/CD, observability, and work with customers to integrate with LIMS/ERP/QMS.

The Staff Software Engineer will design and build user-facing features for clinical AI applications, ensuring quality and security while collaborating cross-functionally.

The Staff Software Engineer will lead feature delivery by building frontend and backend components, focusing on architecture, optimization, security, and performance in a fast-paced environment.

The Staff Software Engineer will build and maintain GoGuardian's Safety product suite, lead architectural decisions, mentor developers, and champion AI adoption in engineering workflows.

The Staff Software Engineer will lead the design of the Integrations Platform's architecture, authoring framework, and integration strategies while coaching other engineers and ensuring high-quality integrations over multiple quarters.

The Staff Software Engineer will architect and implement core services and systems, provide technical leadership, and mentor engineers while focusing on scalable, high-performance software development.

The Staff Software Engineer will design and develop scalable cloud services, focusing on AI infrastructure, with hands-on system architecture, mentoring, and engineering culture shaping responsibilities.

As a Staff Software Engineer, you'll develop and maintain backend systems for Foodsmart's platform, ensuring performance and scalability, while collaborating with front-end teams to support member experiences and clinical workflows.

Lead technical execution of projects, manage the codebase health, adopt AI-driven SDLC, mentor engineers, and ensure quality delivery of full-stack applications.

Design and build agentic LLM pipelines and full-stack AI features. Implement Python/FastAPI backends and TypeScript/React tooling, prompt-engineer models, develop eval datasets and observability, and partner with product teams to deploy reliable production LLM workflows.

As a Staff Software Engineer, you'll design and build backend services, lead system design efforts, mentor engineers, and ensure system quality and reliability.

Lead high-impact initiatives and architect enterprise-grade APIs while mentoring engineers. Collaborate across teams to influence technical strategy and scale platform architecture.

Lead the development of identity and access projects, design authentication systems, engage with stakeholders, and mentor team members.