Top Remote Staff Software Engineer Jobs in Denver & Boulder, CO

Lead design and implementation of developer tooling (SDKs, CLI, workflows), set API governance and technical standards, advocate developer experience across product teams, run community events and livestreams, and deliver high-impact cross-team SDK and platform initiatives to improve reliability, performance, and developer adoption.

Lead the Mapping Engineering team as a Staff Software Engineer, focusing on designing scalable distributed backend systems for autonomous vehicle mapping, collaborating with cross-functional teams, and mentoring engineers.

Join the MongoDB Server Query Optimization team to build a distributed open-source query optimizer, focusing on enhancing query performance and robustness. Responsibilities include innovation in flexible schema databases, mentoring team members, and contributing to the technical roadmap based on extensive experience in the database domain.

Drive the Continuous Integration team, ensuring build systems' reliability and scalability, and mentor CI engineers while improving developer productivity through automation and tooling.

As a Staff Software Engineer, you will lead the development of computer vision systems for sidewalk inspection, overseeing model lifecycle, system architecture, and mentoring while improving deployment practices.

The Staff Software Engineer will lead technical projects for the Patient Matching team, focusing on scalable systems and API design. Responsibilities include system architecture, mentoring engineers, and collaborating with various stakeholders to enhance patient experiences in mental healthcare.

The role involves leading application performance improvements across multiple platforms, focusing on measurable metrics and driving engineering standards and workflow optimization, using both hands-on coding and strategic influence.

The Staff Engineer will lead the Systems team, design scalable cloud infrastructure, optimize data pipelines, and ensure platform reliability and security.

Lead a cross-functional engineering team with hands-on architecture and coding. Mentor engineers, drive technical execution, improve delivery practices, and collaborate with Product and QA to deliver reliable, modern cloud-based AI platform solutions.

Lead the development of high-performance software systems, mentor junior engineers, and contribute to technology strategy while ensuring scalable and maintainable solutions.

Lead full‑stack development for the Care Journey product, owning design and delivery of GraphQL/Python APIs and React/React Native experiences. Write technical specs, drive large cross‑team projects, ensure HIPAA/GDPR compliance, mentor engineers, participate in on‑call, and deliver performant, scalable systems across web and mobile.

Lead end-to-end engineering of an AI-driven biomanufacturing platform: design and deploy LLM-powered agents and RAG systems, build full-stack React/Node/MongoDB pipelines, harden AWS infrastructure for regulated (GxP/Part 11) production, and deploy/integrate with customer LIMS/ERP/QMS.

Lead design and implementation of a production inference platform for LLMs. Define roadmap, integrate and optimize inference runtimes, manage GPU infrastructure, and build systems for deployment, autoscaling, observability, and operational excellence. Benchmark models/runtimes, partner with ML and product teams, make architectural tradeoffs, and mentor engineers to scale AI infrastructure.

The Staff Software Engineer will lead AI integration into software design, develop scalable systems, and mentor other engineers while improving best practices.

The role involves leading the architecture and implementation of hypervisor features, mentoring engineers, and driving technical vision for Lynx's Mosaic platform.

Lead delivery of high-complexity digital banking implementations: design and build Java Spring Boot microservices, REST APIs, cloud-native containerized deployments, data and DB migrations, event streaming, monitoring and performance optimization. Act as a customer-facing technical lead conducting code reviews, test strategies, and cross-functional coordination to resolve operational issues.

Lead the Payments Team by architecting and maintaining high-performance backend services, addressing complex engineering challenges, and mentoring engineering talent.

As a Senior Staff Engineer, you will lead technical vision and architectural direction for Payments Compliance, ensuring scalable and cohesive compliance systems while partnering with cross-functional teams to navigate regulatory requirements.

Act as the technical lead between LQMs and client contracts: diagnose workflows, design and deploy software and infrastructure, wrap scientific logic, integrate agentic systems, and own end-to-end compute and data pipeline deployments to enable scientific delivery.

As a Staff Software Engineer, you will lead technical initiatives for the Core Platform team, focusing on infrastructure and security systems to enhance developer productivity and reliability.

Senior technical leader responsible for architecting and building cloud-native, microservices-based platforms with AI capabilities. Lead design and delivery of scalable search and AI solutions (LLMs, RAG), data pipelines, search optimization (Elastic/OpenSearch/Solr), CI/CD and DevOps adoption, observability, and mentor engineering teams while driving responsible AI practices and stakeholder collaboration.

Design, implement, deploy, and operate scalable backend services, data pipelines, and cloud infrastructure. Influence architecture, mentor engineers, collaborate with data science and product, and improve engineering practices and code quality.

The Security Software Engineer will design and implement security controls for MongoDB Atlas, collaborating across engineering teams and ensuring adherence to high security standards.

Lead design and delivery of enhancements to a next-generation AI agent platform. Own large features and infrastructure, mentor engineers, set technical standards, drive cross-team initiatives, improve reliability and SLOs, and influence product and process decisions to scale systems supporting millions of interactions.

The Staff Software Engineer will focus on quality-driven engineering, automated testing, CI/CD pipelines, AI integration, and mentoring junior engineers while collaborating remotely.