Top Remote Staff Software Engineer Jobs in Denver & Boulder, CO

As a Staff Software Engineer, you'll develop full-stack software applications, mentor team members, and participate in design discussions while advocating for best coding practices.

Lead the technical direction of Care & Onboarding platforms by driving architectural decisions, overseeing large initiatives, and enhancing engineering quality.

As a Fullstack Staff Software Engineer at Babylist, you will lead projects in health technology, mentor team members, and drive impactful decisions using AI and modern tech stacks.

Design, build, and maintain high-throughput data ingestion and processing pipelines; integrate AI-powered infrastructure; implement and support complex computing algorithms and distributed services; own systems end-to-end including architecture, observability, reliability, and operational support; lead architectural initiatives and reduce system complexity while maintaining performance on large-scale real-time data.

Build and operate Coinbase's LLM and agent platform: design the LLM gateway, agent runtime, knowledge bases, AI spend governance, observability/eval tooling, and ship production agents while partnering cross-functionally to ensure secure, cost-effective, and responsible generative AI at scale.

Lead design and implementation of developer tooling (SDKs, CLI, workflows), set API governance and technical standards, advocate developer experience across product teams, run community events and livestreams, and deliver high-impact cross-team SDK and platform initiatives to improve reliability, performance, and developer adoption.

Lead the Mapping Engineering team as a Staff Software Engineer, focusing on designing scalable distributed backend systems for autonomous vehicle mapping, collaborating with cross-functional teams, and mentoring engineers.

Join the MongoDB Server Query Optimization team to build a distributed open-source query optimizer, focusing on enhancing query performance and robustness. Responsibilities include innovation in flexible schema databases, mentoring team members, and contributing to the technical roadmap based on extensive experience in the database domain.

Architect and scale an internal AI platform and APIs to integrate LLMs into developer workflows. Build autonomous agents, RAG systems, and production-grade tooling to boost developer productivity, ensure reliability, security, and cost-efficiency, and collaborate across product, infrastructure, and security teams.

Drive the Continuous Integration team, ensuring build systems' reliability and scalability, and mentor CI engineers while improving developer productivity through automation and tooling.

Lead full‑stack development and architecture for Spark’s broker platform. Deliver customer‑facing features, partner with product/design, mentor engineers, resolve technical debt, and set engineering standards while using AI developer tools.

As a Staff Software Engineer, you will lead the development of computer vision systems for sidewalk inspection, overseeing model lifecycle, system architecture, and mentoring while improving deployment practices.

As a Staff Software Engineer Tech Lead, you will lead technical efforts for the POS app, mentor engineers, solve strategic challenges, and enhance development with AI tools.

As a Staff Software Engineer, you'll design and operate traffic infrastructure, lead multi-team projects, ensure service reliability, and mentor engineers while utilizing AI tools for development efficiency.

The Staff Software Engineer will lead technical projects for the Patient Matching team, focusing on scalable systems and API design. Responsibilities include system architecture, mentoring engineers, and collaborating with various stakeholders to enhance patient experiences in mental healthcare.

Design and develop software solutions enhancing user experience for Governance features, contribute to open-source software, communicate technical designs, and support team quality through reviews.

The Staff Software Engineer will architect and code backend services and ML models, integrate systems, ensure quality, and mentor engineers in the AI & Strategy Engineering team.

The Senior Staff Software Engineer will lead major projects, drive architectural innovation, interface with customers for solutions, and mentor engineers. Experience in software engineering and a strong grasp of AI, cloud scale, and evolving technologies is essential.

Develop and manage high-performance back-end systems, design secure APIs, optimize performance in cloud environments, conduct testing, and manage ML model lifecycles.

Lead technical strategy and execution for multi-quarter initiatives; build and maintain AI-driven systems; mentor and raise the technical bar across teams; collaborate cross-functionally; ensure data security and HIPAA-compliant practices; operate in an AWS + Kubernetes environment while introducing new technologies as system load grows.

Build and lead development of the ESPM platform using Ruby on Rails. Define technical vision, design scalable data pipelines and architectures for petabyte-scale ingestion, implement features across the stack, collaborate with security researchers, mentor engineers, and ensure high-quality, tested deliveries.

Lead technical design and implementation of the ISPM product using Ruby on Rails. Build scalable data pipelines and systems to process large-scale identity telemetry, collaborate with security researchers and product teams, mentor engineers, and set architectural direction for detection and remediation features.

Lead technical strategy and architecture for Coinbase's Blockchain Platform, overseeing nodes, indexers, wallets, and asset lifecycle. Drive cross-team platform rearchitectures, enforce security and reliability standards, champion AI-driven automation, use observability to improve reliability, and represent the platform to executives to secure alignment and resources for large-scale blockchain infrastructure initiatives.

The Staff Software Engineer will architect and develop high-performance cloud services, resolve infrastructure bottlenecks, ensure engineering best practices, and mentor junior members.

The Staff Frontend Engineer will design and implement complex frontend systems, lead engineering efforts, and collaborate with cross-functional teams to deliver a sophisticated SaaS platform.