Top Remote Artificial Intelligence Engineer Jobs in Denver & Boulder, CO

Lead design, build, and deploy of large-scale data platforms for LLMs, RAG, and agentic AI systems. Hands-on coding, architecting fault-tolerant pipelines, establishing MLOps/DataOps best practices, mentoring engineers, and operationalizing research into production across Exabyte-scale distributed systems.

Owns the strategy, architecture, and implementation of production AI and machine learning systems for personalization, search ranking, relevance, and patient-provider matching. Builds recommendation engines, retrieval models, LLM applications, and scalable ML infrastructure while establishing AI safety, evaluation, and MLOps standards. The role requires hands-on model development, technical leadership, mentoring, and responsible deployment of AI in a regulated mental healthcare environment.

Unpaid AI engineering internship to design, build, and deploy ML solutions (NLP, computer vision, recommenders). Work on data preprocessing, model training/fine-tuning, containerized FastAPI microservices, and scalable deployments on Google Cloud Run. Contribute to code reviews, GitHub repos, and integration of third-party AI APIs.

Design, build, deploy, monitor, and optimize production ML and LLM systems, including RAG pipelines, agentic workflows, fine-tuning, and embeddings. Own technical delivery from architecture through iteration, collaborate with client engineering and product teams, mentor junior ML engineers, and help establish internal technical standards and tooling.

The Technical Lead will design, build, and modernize IVR and Voice Bot platforms, providing technical ownership and leadership in a hands-on role within the Contact Center Technology department.

Lead the architecture, development, and scaling of data pipelines and infrastructure for a customer-facing Data Lake platform. Build ETL and ingestion systems using GCP, Debezium, Pub/Sub, Dataflow, BigQuery, Python, Golang, and SQL. Establish engineering standards, deliver strategic projects, mentor engineers, influence cross-functional technical decisions, optimize data services, and shape the platform roadmap.

Build and deploy production AI agents for real customers. Responsibilities include orchestrating LLM pipelines, integrating APIs and tools, developing React interfaces, implementing RAG and document-processing systems, deploying serverless applications, and monitoring performance. The role requires strong Python or JavaScript skills, hands-on OpenAI and multimodal LLM experience, vector databases, agent frameworks, function calling, and full-stack integration. Applicants must be pursuing a Master's or PhD in a technical field.

The Staff AI Engineer will analyze AI quality, implement improvements, manage projects, collaborate with teams, and shape AI capabilities in a remote-first environment.

Build and operationalize production AI solutions for federal clients, from stakeholder discovery and architecture through evaluation, deployment, governance, monitoring, and optimization. Develop LLM applications using retrieval, structured outputs, tool use, and agentic workflows. Define quality metrics, create evaluation sets, document limitations, advise clients on AI use cases, and mentor engineers while contributing to reusable internal patterns and products.

Owns AI capabilities end to end, from stakeholder discovery and technical design through development, evaluation, deployment, monitoring, and documentation. Builds LLM applications using retrieval, structured extraction, tool use, and agent patterns; defines measurable quality criteria; balances accuracy, cost, latency, security, and complexity; supports client delivery and proofs of concept; and mentors engineers new to AI.

Build production-quality AI applications for federal clients and internal products. Responsibilities include gathering requirements, designing prompts and retrieval workflows, integrating APIs and data, creating evaluations, investigating failures, documenting limitations, and supporting proofs of concept and client demonstrations. The role requires client-facing communication, comfort with ambiguity, and the ability to translate business needs into working software.

Build production-ready agentic AI applications that solve customer problems. Design workflows, plugins, and tool integrations; translate ambiguous needs into intuitive AI experiences; rapidly iterate applications into production; integrate APIs and enterprise systems; and partner with platform and product engineers. Own customer-facing quality, including user experience, reliability, performance, and evaluation, while identifying reusable patterns across deployments.

Lead Affirm’s enterprise AI security review program, threat model LLM and agentic systems, review code and configurations, and develop security guardrails, tooling, policies, and monitoring. Evaluate AI-enabled SaaS vendors, identify emerging vulnerabilities, support incident response, and lead cross-functional initiatives across Security, Engineering, Legal, Privacy, and Compliance. The role requires expertise in AI security architecture, threat modeling, IAM, cloud infrastructure, policy-as-code, and regulated enterprise environments.

Lead DigitalOcean’s AI security strategy, governance framework, and multi-year roadmap. Secure AI/ML systems across data ingestion, training, model serving, RAG, agents, and monitoring. Conduct threat modeling, adversarial testing, AI red teaming, and security reviews; develop guardrails and automation with engineering teams. Advise executives and the board on AI risk, define organizational controls, and guide responses to emerging threats including prompt injection, model supply-chain risks, and AI-enabled social engineering.

Build foundational systems for AI models across data modalities, develop agentic systems and specialized models, and implement reinforcement learning and active inference solutions. The role involves hands-on architecture and product development, requiring Python backend expertise, cloud deployment knowledge, DevOps practices, and the ability to contribute across the technical stack in an early-stage startup.

Create reinforcement learning environments to evaluate AI systems solving complex software engineering tasks with MCP tools. Responsibilities include designing reproducible environments, deterministic verification, golden reference solutions, bug fixes, feature implementation, codebase refactoring, and performance optimization across software codebases.

Build and own conversational voice AI products end-to-end: architect, implement, and deploy the platform. Design infrastructure, develop front-end and back-end systems, deliver reliable customer outcomes, and collaborate directly with the CTO to scale the product for enterprise customers.

Design, build, test, deploy, monitor, and maintain production LLM-based agentic solutions for Commercial Customer Success. Integrate agents with CRMs and Samsara systems, define evaluation frameworks and success metrics, implement automated tests and monitoring, iterate on models and prompts, and demonstrate impact on customer outcomes and retention.

Designs, develops, and operates enterprise-grade platforms for AI agents and Generative AI applications. Responsibilities include agent orchestration, LLM and AI service integration, secure tool and API invocation, prompt lifecycle management, governance and safety controls, observability, model evaluation, deployment, troubleshooting, and platform optimization. The role collaborates with engineering, security, product, and data teams to deliver scalable, reliable, and compliant AI solutions.

Own product-layer performance for agentic AI systems in healthcare. Design prompting, retrieval, context, memory, tool use, evaluation, escalation, and human-review workflows. Build production-grounded evaluations, diagnose failures, improve accuracy, reliability, latency, cost, and steerability, and approve model changes. Partner with Product and Engineering while maintaining model cards, intended-use guidance, limitations, and failure-mode documentation for safe, transparent deployment.

Build and modernize enterprise data and AI ecosystems, including real-time streaming pipelines, data products, semantic layers, knowledge graphs, RAG architectures, and GenAI infrastructure. Develop synthetic data workflows, automated data quality systems, and reliable cloud data platforms. Collaborate with architects, DevOps, and stakeholders, mentor engineers, lead prototypes, and apply AI solutions to insurance use cases while ensuring scalability, governance, monitoring, and operational resilience.

Build and deploy AI-powered solutions across Sales, Marketing, and Customer Support. Diagnose workflows, identify constraints, evaluate whether AI is appropriate, and own initiatives from discovery through deployment. Develop LLM applications using prompt engineering, RAG, agentic architectures, orchestration, guardrails, and enterprise integrations. Measure business value through flow metrics, adoption, ROI, and feedback loops while partnering with technical and non-technical stakeholders.

Design, deploy, and operate production clinical AI agents that synthesize patient data, retrieve clinical knowledge, use tools, generate care recommendations, and escalate to clinicians. Own LLM workflow reliability, observability, cost efficiency, evaluation, safety testing, RAG optimization, orchestration, and lifecycle management. Collaborate with clinical, product, and engineering teams to build reliable AI systems for chronic disease care.

Leads architecture, development, and delivery of secure cloud, data, process intelligence, and AI solutions for federal clients. Builds AWS cloud-native services, scalable data platforms, Celonis process-mining solutions, and agentic AI workflows using Amazon Bedrock and Azure OpenAI. Owns technical direction, engineering standards, security, testing, observability, deployment automation, and reusable product packaging. Supports A-123 continuous controls monitoring, agency implementations, demonstrations, and cloud environment deployments while collaborating with AWS and Celonis partners.

Provides technical leadership and architectural oversight for scalable AI-integrated software. Designs agentic AI systems, MCPs, APIs, RAG solutions, microservices, and prompt strategies; decomposes product goals into engineering tasks; reviews human- and AI-generated code; mentors distributed developers; and improves DevOps and CI/CD pipelines with AI-enhanced testing and reviews.