Top Remote Artificial Intelligence Engineer Jobs in Denver & Boulder, CO

As an AI Engineer, you will build and scale AI business applications, focusing on generative AI. Responsibilities include rapid prototyping, applying software engineering best practices, and providing production support.

The AI Engineer Manager leads the Data and Analytics Engineering team in developing AI solutions, manages client accounts, analyzes data, and fosters team leadership and relationships with clients.

Lead design and implementation of agentic AI workflows and integrations for Acquia DAM. Build, ship, and observe production AI features (auto-tagging, search, governance), set AI engineering standards, evaluate models and tooling, mentor engineers, and represent AI architecture to product and customers.

Take Deepgram's speech models and optimize, compile, and run them on resource-constrained embedded and edge hardware. Work across model compression, runtime performance (C/C++/Rust), RTOS/bare-metal and embedded Linux environments, vendor NPUs/DSPs and inference runtimes, benchmarking, deployment pipelines, OTA updates, and partner with silicon vendors to enable real-time, low-power on-device voice experiences.

As a Senior AI Engineer, you'll design and implement AI-driven solutions, focusing on full-stack development and production-grade applications while mentoring junior team members.

Architect and scale an internal AI platform and APIs to integrate LLMs into developer workflows. Build autonomous agents, RAG systems, and production-grade tooling to boost developer productivity, ensure reliability, security, and cost-efficiency, and collaborate across product, infrastructure, and security teams.

As a Principal AI Engineer, you'll design production-grade systems integrating generative AI in mental healthcare, overseeing architecture and applied research.

Design and implement AI capabilities, transition prototypes to production, build agent workflows, optimize data retrieval, and automate evaluation processes.

Design, prototype, and deploy LLM-powered agents, RAG workflows, and automations that accelerate internal teams and customer-facing product features. Integrate AI systems with SaaS tools, build reusable components and evaluation frameworks, embed with business teams to deliver measurable outcomes, and establish standards for responsible AI, monitoring, and cost control across the company.

Lead the development of innovative AI solutions, guide teams through complex challenges, and collaborate with diverse stakeholders to enhance operational effectiveness and achieve strategic objectives.

This role involves defining AI architecture, improving system quality, leading teams, and building production-ready AI systems at Drata.

Lead architecture and delivery of AI-native features for a multi-tenant SaaS platform. Drive cross-functional technical initiatives, design scalable microservice systems, integrate LLMs and agent frameworks, set engineering standards, and mentor engineers to elevate technical execution.

The role involves designing AI systems for mental healthcare, focusing on building scalable, production-grade systems that enhance patient engagement and clinical operations. Responsibilities include setting technical standards and ensuring safety and reliability while working with advanced AI technologies.

Architect and implement enterprise GenAI platforms (RAG and agentic systems), design knowledge retrieval, orchestration, tool-using agents and human-in-the-loop workflows, ensure production readiness and governance with product/data/security teams, define platform engineering best practices, and solve complex platform challenges with broad autonomy.

As a Staff AI Engineer, you'll lead AI product development, overseeing technical direction, system deployment, and model evaluation while collaborating across teams.

Build the core AI platform and high-performance Rust backend powering an AI-native trading copilot. Implement streaming responses, low-latency tool execution, caching, orchestration of models and tools, secure APIs, auditing/tracing, and safe, auditable trading action infrastructure. Partner with product and frontend to enable AI-native UX and translate trading domain requirements into resilient platform primitives.

Lead ownership of reliability, evaluation, and safety for an AI copilot in a trading platform. Build eval systems, benchmarks, automated quality gates, monitoring, and model improvement loops; partner with engineering and product to define safe tool contracts and ensure predictable, auditable assistant behavior in trading workflows.

Build end-to-end full-stack AI features on a Ruby on Rails backend and React frontend, design and run experiments (A/B tests and AI evaluations), implement AI infrastructure for reliable LLM inference, and iterate quickly to scale production-ready LLM-powered products.

The AI Automation Lead will architect and deliver multi-agent AI workflows, develop full-stack applications, and lead technical decisions across engineering teams.

The Principal AI/ML Engineer will develop machine learning models for campaign optimization in AdTech, collaborating across engineering and product teams to enhance advertising capabilities.

Design, build, deploy, and maintain scalable, resilient backend services for a Voice AI platform. Lead cross-cutting projects, make architectural decisions, integrate AI platforms, implement observability and evaluation frameworks, and mentor engineers.

Design, build, deploy, and iterate production-ready AI agents and LLM-based solutions that integrate with enterprise workflows. Rapidly prototype, evaluate, and optimize agents for performance, cost, and adoption. Partner across functions to redesign workflows, contribute to an AI Center of Excellence, and ensure responsible, secure, and scalable agent development.

Design, build, and operate large-scale LLM infrastructure and data platforms for training, fine-tuning, and inference. Provision GPU clusters, optimize GPU utilization, implement model lifecycle management, deploy inference frameworks, create evaluation and observability systems, and collaborate with data scientists to productionize AI capabilities. Mentor engineers and enforce MLOps/DataOps best practices.

Build and scale AI platform infrastructure for internal agents across AWS/GCP. Integrate identity (Okta, OAuth2/OIDC), implement agentic security, containerized deployments (Docker/Kubernetes), CI/CD and Terraform-based pipelines, run vendor evaluations, and design observability/telemetry for LLM-driven workflows while collaborating with security, identity, and engineering teams.

Design, build, and deploy AI agents and multi-step automation workflows for Client Experience. Integrate systems via APIs, partner with stakeholders, ensure governance and security, and track metrics for efficiency and customer outcome improvements.