Top Remote Artificial Intelligence Engineer Jobs in Denver & Boulder, CO

Architects and develops AI-powered systems, tools, agents, backend services, APIs, and experimentation frameworks using foundational AI models. Integrates AI capabilities with microservices, AWS, Snowflake, and complex data systems while ensuring scalability, reliability, and maintainability. Translates business problems into technical solutions, prototypes AI applications, collaborates with product and engineering teams, evaluates emerging AI technologies, and documents system designs and integration patterns.

Design and deploy production AI assistants, copilots, agents, RAG systems, and workflow automation using enterprise data. Build AI backend services, APIs, microservices, and AWS serverless workflows; integrate enterprise platforms; implement observability, responsible AI, human-in-the-loop controls, and traceability. Partner with Data, IT, and business teams to improve operational processes and decision-making while managing production incidents, model rollbacks, performance, accuracy, and cost.

Build and ship production AI systems across retrieval, knowledge graphs, inference, agentic workflows, and data platforms. Develop customer-context retrieval, scored signals, evaluation and observability capabilities, and workflows that turn insights into action. Work hands-on with large and small models, durable orchestration, cloud deployment, inference-cost optimization, and high-volume observability data. Establish reusable engineering patterns, collaborate with product and platform teams, and mentor through strong technical contributions.

Build production AI agents and agent-powered features from research and prototyping through deployment. Develop evaluation infrastructure with golden datasets, regression suites, and offline/online scoring. Own retrieval and context pipelines, production instrumentation, failure taxonomies, and cost and latency budgets. Partner with data science and product management on experiments and agent behavior, while establishing LLM engineering patterns, guardrails, and reusable tooling.

Owns the strategy, architecture, and implementation of production AI and machine learning systems for personalization, search ranking, relevance, and patient-provider matching. Builds recommendation engines, retrieval models, LLM applications, and scalable ML infrastructure while establishing AI safety, evaluation, and MLOps standards. The role requires hands-on model development, technical leadership, mentoring, and responsible deployment of AI in a regulated mental healthcare environment.

Design, build, test, deploy, monitor, and maintain production LLM-based agentic solutions for Commercial Customer Success. Integrate agents with CRMs and Samsara systems, define evaluation frameworks and success metrics, implement automated tests and monitoring, iterate on models and prompts, and demonstrate impact on customer outcomes and retention.

Own product-layer performance for agentic AI systems in healthcare. Design prompting, retrieval, context, memory, tool use, evaluation, escalation, and human-review workflows. Build production-grounded evaluations, diagnose failures, improve accuracy, reliability, latency, cost, and steerability, and approve model changes. Partner with Product and Engineering while maintaining model cards, intended-use guidance, limitations, and failure-mode documentation for safe, transparent deployment.

Build and deploy AI-powered solutions across Sales, Marketing, and Customer Support. Diagnose workflows, identify constraints, evaluate whether AI is appropriate, and own initiatives from discovery through deployment. Develop LLM applications using prompt engineering, RAG, agentic architectures, orchestration, guardrails, and enterprise integrations. Measure business value through flow metrics, adoption, ROI, and feedback loops while partnering with technical and non-technical stakeholders.

Hands-on technical leader who designs, builds, and deploys production-grade AI automation and agentic workflows. Responsibilities include rapid prototyping, RAG and document-intelligence systems, API integrations, orchestration, monitoring, reusable AI assets, and mentoring a small engineering team to deliver frequent releases and measurable business impact.

Build AI-powered workflows, agents, integrations, and internal tools that automate People Operations. Partner with People, Engineering, and IT to modernize onboarding and other employee processes, while implementing secure access controls, human oversight, escalation paths, and production-ready architectures. Prototype with users, iterate quickly, and measure improvements in efficiency, employee experience, and operational consistency.

Build and ship production-grade agentic AI workflows across Acquia’s digital experience platform. Architect stateful multi-agent systems using LangGraph, Temporal, and Pydantic; own LangFuse observability, evaluation, and prompt management; establish standards for RAG and tool calling; partner on secure, reliable enterprise architectures; evaluate AI tooling; mentor engineers; and support customer architecture and roadmap discussions.

Take Deepgram's speech models and optimize, compile, and run them on resource-constrained embedded and edge hardware. Work across model compression, runtime performance (C/C++/Rust), RTOS/bare-metal and embedded Linux environments, vendor NPUs/DSPs and inference runtimes, benchmarking, deployment pipelines, OTA updates, and partner with silicon vendors to enable real-time, low-power on-device voice experiences.

Engineer AI-powered threat detections, automated response playbooks, and continuous adversary emulation. Apply machine learning and LLMs to security operations, conduct threat hunting and AI red teaming, map coverage to MITRE ATT&CK, and develop detection-as-code through CI/CD. Build production-grade Python integrations, measurable containment capabilities, and safe autonomous defenses with guardrails. Mentor security professionals and collaborate across threat response, cyber defense engineering, and platform teams.

Design, build, and operate agentic AI systems end-to-end for Professional Services. Translate stakeholder needs into secure, scalable multi-agent architectures, define performance benchmarks, manage deployments and incident response, advise leadership, mentor teammates, and maintain runbooks and production tooling including on-call responsibilities.

Build and productionize agentic workflows, RAG pipelines, AI services, backend systems, and ML pipelines for sales automation. Integrate Salesforce, quoting engines, data lakes, and internal platforms using scalable, event-driven architectures. Lead 0-to-1 development of tools for account research, lead prioritization, and quoting while ensuring reliability, observability, performance, and resilience across the GTM technology stack.

Build AI-augmented BI dashboards, semantic layers, and AI-ready metadata. Use AI-assisted tools to accelerate SQL and dashboard development, productionize ML outputs into BI, enforce data quality and governance, and present insights to business stakeholders including C-suite.

Leads Wasabi’s AI infrastructure, data factory, and developer partnerships strategy. Hunts and originates new relationships, develops joint go-to-market and co-selling motions, structures revenue-generating deals, and manages executive partner relationships. The role collaborates with Business Development, Sales, Marketing, and Product, builds the developer ecosystem, tracks pipeline and revenue performance, and represents Wasabi at industry events. Candidates need deep AI infrastructure and storage expertise, an established industry network, and a proven record of closing strategic partnerships.

Build reference software codebases, support NGOs developing generative AI products, integrate diverse data sources, create experimentation tools, and deliver rapid cloud-based solutions. The role includes advising and mentoring partner organizations, conducting rigorous experiments, improving analytics infrastructure, organizing technical workshops, and visiting NGO sites to identify technical needs. Candidates need strong full-stack engineering, backend, data engineering, cloud, database, and generative AI experience.

Lead architecture and implementation of autonomous inbound/outbound AI agents, build scalable LLM ops and signal-intelligence data pipelines, integrate identity resolution and third-party CRM systems, and maintain production-ready, well-documented systems for Series B diligence.

Design, prototype, and deploy LLM-powered agents, RAG workflows, and automations that accelerate internal teams and customer-facing product features. Integrate AI systems with SaaS tools, build reusable components and evaluation frameworks, embed with business teams to deliver measurable outcomes, and establish standards for responsible AI, monitoring, and cost control across the company.

Lead the architecture, development, and deployment of scalable AI-powered backend systems. Design APIs and inference workflows, fine-tune and productionize LLM and transformer models, establish MLOps and governance standards, and evaluate AI technologies. Mentor engineers, guide cross-functional technical initiatives, improve system reliability and performance, and shape the organization’s AI strategy and roadmap.

Design, build, and deploy Microsoft Copilot and Power Platform solutions (PowerApps, Power Automate, Dataverse) and locally-run AI tooling (Claude). Provide solution architecture, prompt engineering, integrations (Graph API/REST), compliance with Azure/Entra/Purview/DLP, mentoring, testing, and adoption support within regulated environments.

Develops, configures, tests, and supports AI solutions, workflows, integrations, and model-enabled applications. Creates technical instructions and documentation, troubleshoots and optimizes AI systems, coordinates technical tasks, and collaborates with architects, delivery leaders, project teams, and stakeholders. Requires a college degree or equivalent, three years of related experience, technical communication skills, and the ability to travel and participate in on-call availability.

Develop, deploy, and operate machine learning and generative AI solutions across AWS, Azure, GCP, and OCI. Build ML pipelines, data workflows, model-serving infrastructure, and cloud-native AI integrations. Monitor model performance, drift, bias, reliability, and costs while troubleshooting production workloads. Collaborate with data scientists, developers, and infrastructure teams, document architectures and procedures, and follow governance, compliance, and change-management practices for federal government environments.

Design and implement multi-step agentic AI workflows (orchestration, retrieval, tool use, state management) using frameworks like LangGraph/LangChain. Build retrieval pipelines over proprietary CRE data, evaluate and monitor model quality with human-in-the-loop processes, integrate Anthropic models on AWS Bedrock, implement guardrails and observability, and rapidly prototype features with Product and Design to deliver trustworthy, source-linked AI capabilities that perform real business actions.