Top Remote Artificial Intelligence Engineer Jobs in Denver & Boulder, CO

As a Staff AI Engineer, you'll lead AI product development, overseeing technical direction, system deployment, and model evaluation while collaborating across teams.

The role involves designing AI systems for mental healthcare, focusing on building scalable, production-grade systems that enhance patient engagement and clinical operations. Responsibilities include setting technical standards and ensuring safety and reliability while working with advanced AI technologies.

Hands-on technical leader who designs, builds, and deploys production-grade AI automation and agentic workflows. Responsibilities include rapid prototyping, RAG and document-intelligence systems, API integrations, orchestration, monitoring, reusable AI assets, and mentoring a small engineering team to deliver frequent releases and measurable business impact.

Take Deepgram's speech models and optimize, compile, and run them on resource-constrained embedded and edge hardware. Work across model compression, runtime performance (C/C++/Rust), RTOS/bare-metal and embedded Linux environments, vendor NPUs/DSPs and inference runtimes, benchmarking, deployment pipelines, OTA updates, and partner with silicon vendors to enable real-time, low-power on-device voice experiences.

Own end-to-end voice platform migration and scaling: LiveKit migration, real-time turn-taking, VAD, SIP/WebRTC, multi-agent handoff, training/fine-tuning voice models, inference cost optimization, and retrieval-based grounding using Supabase/pgvector.

Architect and scale an internal AI platform and APIs to integrate LLMs into developer workflows. Build autonomous agents, RAG systems, and production-grade tooling to boost developer productivity, ensure reliability, security, and cost-efficiency, and collaborate across product, infrastructure, and security teams.

Design and scale a reusable Customer Success AI platform: build foundational AI infrastructure (orchestration, memory, context, workflow engines), optimize model routing, observability, governance, and security, lead architecture and standards, mentor engineers, and partner cross-functionally to deliver enterprise-grade, multi-product AI capabilities.

Design, prototype, and deploy LLM-powered agents, RAG workflows, and automations that accelerate internal teams and customer-facing product features. Integrate AI systems with SaaS tools, build reusable components and evaluation frameworks, embed with business teams to deliver measurable outcomes, and establish standards for responsible AI, monitoring, and cost control across the company.

This role involves defining AI architecture, improving system quality, leading teams, and building production-ready AI systems at Drata.

Lead technical direction and architecture for DAP Repository Flows, design and ship autonomous and scheduled agents that operate on customer repositories, improve DAP onboarding, collaborate across teams on platform interfaces, mentor engineers, and solve high-scale technical problems to raise engineering quality.

Lead design, build, and deploy of large-scale data platforms for LLMs, RAG, and agentic AI systems. Hands-on coding, architecting fault-tolerant pipelines, establishing MLOps/DataOps best practices, mentoring engineers, and operationalizing research into production across Exabyte-scale distributed systems.

Own and improve the AI Social render pipeline and agent loops that generate on-brand Instagram carousels and reels. Build prompts, structured outputs, tool-calling, and media composition to ship high-quality generative image, video, voice, and music products in collaboration with product, design, and content strategy.

Build and operate Coinbase's LLM and agent platform: unified model gateway, AI Hub, secure microVM agent runtime, knowledge base integrations, AI FinOps, observability and evaluation tooling, and production-grade agent deployments with teams across the company.

Design, build, and operate agentic AI systems end-to-end for Professional Services. Translate stakeholder needs into secure, scalable multi-agent architectures, define performance benchmarks, manage deployments and incident response, advise leadership, mentor teammates, and maintain runbooks and production tooling including on-call responsibilities.

The Principal AI/ML Engineer will develop machine learning models for campaign optimization in AdTech, collaborating across engineering and product teams to enhance advertising capabilities.

Design, build, and operate large-scale LLM infrastructure and data platforms for training, fine-tuning, and inference. Provision GPU clusters, optimize GPU utilization, implement model lifecycle management, deploy inference frameworks, create evaluation and observability systems, and collaborate with data scientists to productionize AI capabilities. Mentor engineers and enforce MLOps/DataOps best practices.

Design, build, deploy, and iterate production-ready AI agents and LLM-based solutions that integrate with enterprise workflows. Rapidly prototype, evaluate, and optimize agents for performance, cost, and adoption. Partner across functions to redesign workflows, contribute to an AI Center of Excellence, and ensure responsible, secure, and scalable agent development.

Lead architecture and delivery of AI-native features for a multi-tenant SaaS platform. Drive cross-functional technical initiatives, design scalable microservice systems, integrate LLMs and agent frameworks, set engineering standards, and mentor engineers to elevate technical execution.

Design, build, deploy, and maintain scalable, resilient backend services for a Voice AI platform. Lead cross-cutting projects, make architectural decisions, integrate AI platforms, implement observability and evaluation frameworks, and mentor engineers.

Build and scale AI platform infrastructure for internal agents across AWS/GCP. Integrate identity (Okta, OAuth2/OIDC), implement agentic security, containerized deployments (Docker/Kubernetes), CI/CD and Terraform-based pipelines, run vendor evaluations, and design observability/telemetry for LLM-driven workflows while collaborating with security, identity, and engineering teams.

Build end-to-end full-stack AI features on a Ruby on Rails backend and React frontend, design and run experiments (A/B tests and AI evaluations), implement AI infrastructure for reliable LLM inference, and iterate quickly to scale production-ready LLM-powered products.

Build the core AI platform and high-performance Rust backend powering an AI-native trading copilot. Implement streaming responses, low-latency tool execution, caching, orchestration of models and tools, secure APIs, auditing/tracing, and safe, auditable trading action infrastructure. Partner with product and frontend to enable AI-native UX and translate trading domain requirements into resilient platform primitives.

Lead ownership of reliability, evaluation, and safety for an AI copilot in a trading platform. Build eval systems, benchmarks, automated quality gates, monitoring, and model improvement loops; partner with engineering and product to define safe tool contracts and ensure predictable, auditable assistant behavior in trading workflows.

As a Principal Data Engineer, you will design and implement LLM, AI-powered security data platforms, mentor engineers, and drive the adoption of data solutions across teams.

Design, develop, and deploy AI/ML models and pipelines; collaborate with teams to integrate models via APIs or microservices; monitor model performance and ensure scalable production deployments.