Top Machine Learning Jobs in Denver & Boulder, CO

Design, build, and support high-throughput, low-latency LLM inference and data pipelines; collaborate with data scientists to post-train and evaluate models; implement scalable, production-ready systems with strong testing, monitoring, and performance focus; mentor engineers and iterate on architecture, reliability, and user-facing AI applications.

Lead research and engineering of production-grade LLM/GenAI systems for cybersecurity: design models and architectures, drive data labeling and evaluation, collaborate with product and engineering to deploy scalable solutions, mentor data scientists, set technical strategy, and advance AI safety, red-teaming, and applied ML innovations for detection and operational use.

Lead development and deployment of large-scale LLM and GenAI solutions for cybersecurity. Drive research strategy, model training, evaluation, safety/red-teaming, and cross-functional productization. Mentor data scientists, set technical standards, and represent the team through publications and thought leadership.

As a Staff Machine Learning Engineer, you will design AI products on Edge devices, optimize ML model performance, and work with large-scale datasets, collaborating across teams to deliver impactful solutions.

As an ML Ops Infrastructure Engineer, you will design CI/CD pipelines for ML, maintain deployment systems, and implement monitoring while collaborating with research teams to ensure model quality and performance.

The Sr. Machine Learning Engineer will develop and deploy ML solutions for healthcare, manage data pipelines, and work with large datasets to enhance healthcare delivery.

As a Staff Applied ML Scientist, you will develop and maintain fraud detection models, conduct research on fraud types, and collaborate across teams to drive product development and real-time decision-making.

As a Senior Applied ML Scientist, you'll develop fraud detection models, research new fraud types, and write production code while collaborating across teams to enhance SentiLink's identity verification solutions.

Design, train, and productionize machine learning models for fraud and identity risk across the full ML lifecycle. Research new fraud types, perform feature engineering and labeling, write production-ready code for real-time decisioning, monitor models, and provide analyses to inform product, sales, and data acquisition.

Lead and deliver complex, cross-team AI product programs, drive agent-first SDLC adoption, ensure integration and operational readiness of AI workflows, define metrics, communicate risks and status, and standardize TPM best practices across Product and Engineering.

Lead and align ML, data, and engineering teams to define multi-year AI roadmaps, deliver production ML solutions, ensure robust data pipelines, set success metrics tied to business outcomes, and grow/mentor senior managers and engineers.

Build, ship, and own end-to-end ML models for vendor matching, order routing, and supply-chain optimization. Partner with data engineering to productionize models, quantify impact, document work, and implement decision logic components toward agentic AI in a fast-moving healthcare startup environment.

Lead and build a data science organization to create a prediction engine for vendor matching, order routing, and supply chain optimization. Anchor projects to P&L, design measurement and experiment frameworks, ship rapid wins, hire and coach data scientists, work hands-on in modeling and technical design, partner with product and engineering (Snowflake), and evolve systems toward agentic AI while reporting impact in dollar terms.

Own end-to-end modeling for vendor matching, order routing, and supply-chain optimization. Build predictive, causal, RL and OR solutions; design autonomous decision logic; quantify counterfactual impact; ship production models with data engineering; mentor senior data scientists; write technical design docs; partner on quarterly priorities and expand into revenue cycle and finance domains.

Oversee global analytics and algorithm design initiatives for a nonprofit: identify high-impact projects, coordinate with student directors, collect feedback, design and run training for developers and technical advisors, and form partnerships to support implementation. Volunteer commitment ~5-6 hours/week.

Design and build reinforcement-learning training environments and diverse tasks to evaluate and improve LLM agents; iterate rapidly on task designs from customer feedback, deliver high-quality outputs with minimal supervision, and maintain PST overlap for collaboration.

Build and scale Gusto's ML/AI platform: design MLOps solutions, automated pipelines, model development frameworks, deployment, monitoring, CI/CD, and observability; collaborate with ML engineers and apply AI tools and best practices to production ML systems.

Lead and deliver complex, cross-team AI platform programs: manage schedules, risks, integration of AI workflows and agents, enable operational readiness, drive TPM best practices, and communicate status and metrics to stakeholders in a remote, multi-timezone environment.

Lead development of time-series and econometric models (ARIMA, VAR, state-space, WLS, panel data) and Bayesian probabilistic frameworks. Use causal inference and stochastic processes to produce actionable insights, work with large datasets on Databricks, communicate results to stakeholders, and mentor junior team members.

As a Senior Technical Product Manager, you will lead the AI Platform team to define roadmaps, collaborate with technical experts, and improve healthcare delivery by leveraging AI technologies.

Drive independent, high-impact research on frontier AI topics, publish findings, collaborate widely, and mentor new researchers in the field.

Design, build, and deploy conversational agents using Microsoft Copilot Studio. Gather stakeholder requirements, implement NLU/NLP, integrate with enterprise systems, test and refine agents, and provide documentation and user support for HR, policy retrieval, and procure-to-pay automations.

Design and implement conversational AI solutions using NLP, ML, and LLMs. Build ETL pipelines and integrate relational and NoSQL databases. Develop Voice AI interactions on Vertex AI, work with Nuance IVR and Microsoft platforms, and write production-grade Python code.

Design, build, and deploy conversational AI solutions on the Kore.AI platform. Create and configure chatbots (intents, entities, dialog flows), integrate with back-end systems and REST APIs, and develop responsive user interfaces using ReactJS alongside UI/UX designers.

Lead architecture and engineering for AI-powered applications across backend, mobile, and desktop. Own reliability, observability, APIs, and model integrations. Grow and mentor a small senior applications team, drive production readiness, and make high-impact tradeoffs across latency, cost, security, and user experience to deliver reliable, low-latency AI-enabled workflows.