GeneDx (Nasdaq: WGS) delivers personalized and actionable health insights to inform diagnosis, direct treatment, and improve drug discovery. The company is uniquely positioned to accelerate the use of genomic and large-scale clinical information to enable precision medicine as the standard of care. GeneDx is at the forefront of transforming healthcare through its industry-leading exome and genome testing and interpretation services, fueled by the world’s largest, rare disease data sets. For more information, please visit www.genedx.com.
Summary
GeneDx, the world's leading genomics diagnostics company, is seeking a Senior Software Engineer to join our Data Applications team within our Data Platform organization. In this role, you will be responsible for collaboratively designing, developing, and maintaining our data-centric applications.
You will be the technical thought leader on a supportive and cross-functional team with well-defined roles and responsibilities. You will work with Product Managers and Designers to understand your key user personas (both internal to the company and external), their pain points, and how our applications can better enable their workflows. You will work with other technical leads and engineers to break down, estimate, implement, and document both technical and user-centered requirements. As a thought leader, you will lead the team in determining architectural approaches, identifying technical dependencies, overseeing the maintenance of technical debt, and guiding your more junior peers.
Job Responsibilities
- Design, develop, test, and maintain scalable and robust data applications using Python, React, Next.js, and PostgreSQL.
- Collaborate with the team to understand requirements, empathize with our users, and translate that information into technical solutions.
- Develop and optimize database schemas, queries, and data processing pipelines to ensure high performance and data integrity.
- Implement intuitive and responsive user interfaces for data analysis, visualization, and reporting using modern web technologies.
- Identify and address performance bottlenecks, security vulnerabilities, and other technical challenges.
- Participate in code reviews, mentor more junior engineers, and provide constructive feedback to maintain code quality and best practices.
The Objectives
- Be a key contributor to building out the new Clinical Operations Platform; a suite of applications which empower our Clinical Team to ultimately help more patients at a cheaper cost via automation.
- Ensure that existing and new Clinical Operations applications meet the highest standard of industry best practices possible such that they are scalable, performant, flexible, secure, and reusable. All while maintaining minimal technical debt.
Education, Experience, and Skills
- Bachelor's or Master's degree in Computer Science, Software Engineering, or a related field.
- 8+ years of professional experience in full stack development. A focus on building clinical-centric applications is a plus.
- Strong proficiency in Python (or similar backend language) and Next.js, React (or similar front-end framework), with a proven track record of delivering high-quality, scalable, performant, and maintainable code.
- Strong Proficiency in SQL for complex data retrieval, manipulation, and analysis. Bonus points for designing schemas, optimizing queries, and ensuring data integrity.
- Any experience working in the health-tech, genetics, and/or bioinformatics space is a plus.
- Familiarity with cloud platforms (e.g., AWS, Azure, GCP) and DevOps practices is desirable.
- Strong problem-solving skills, with the ability to debug and resolve complex technical issues efficiently.
- Excellent communication and collaboration skills, with the ability to work effectively in a team-oriented environment.
- Proven ability to take ownership of projects and drive them to completion, meeting deadlines and delivering high-quality results.
- Proven ability to mentor teammates and drive architectural decisions for applications within a broader platform
Certificates, Licenses, Registrations
- None
Physical Demands
This is a sedentary role that requires prolonged sitting while working at a computer. Physical demands include:
- Sitting for extended periods (up to 8 hours per day)
- Repetitive use of hands and fingers for typing and mouse operation
- Visual acuity for reading computer screens and documents
- Ability to communicate effectively via phone and video calls
- Occasional lifting of up to 10 pounds (office supplies, equipment)
Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions of this position.
Work Environment
This is a fully remote position. The employee will work from a home office or other suitable remote location with reliable high-speed internet access. Work is performed in a climate-controlled environment using standard office equipment, including a computer, phone, and video conferencing tools. Your standard work schedule and hours will be established in collaboration with your leader and may be adjusted to align with evolving business needs.
Acknowledgements
The above job description is not intended to be an all-inclusive list of duties and standards of the position. Incumbents will follow any other instructions and perform any other related duties, as assigned by their supervisor.
#LI-REMOTE
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Science - Minded, Patient - Focused.
At GeneDx, we create, follow, and are informed by cutting-edge science. With over 20 years of expertise in diagnosing rare disorders and diseases, and pioneering work in the identification of new disease-causing genes, our commitment to genetic disease detection, discovery, and diagnosis is based on sound science and is focused on enhancing patient care.
Experts in what matters most.
With hundreds of genetic counselors, MD/PhD scientists, and clinical and molecular genomics specialists on staff, we are the industry’s genetic testing experts and proud of it. We share the same goal as healthcare providers, patients, and families: to provide clear, accurate, and meaningful answers we all can trust.
SEQUENCING HAS THE POWER TO SOLVE DIAGNOSTIC CHALLENGES.
From sequencing to reporting and beyond, our technical and clinical experts are providing guidance every step of the way:
TECHNICAL EXPERTISE
- High-quality testing: Our laboratory is CLIA certified and CAP accredited and most of our tests are also New York State approved.
- Advanced detection: By interrogating genes for complex variants, we can identify the underlying causes of conditions that may otherwise be missed.
CLINICAL EXPERTISE
- Thorough analysis: We classify variants according to our custom adaptation of the most recent guidelines. We then leverage our rich internal database for additional interpretation evidence.
- Customized care: Our experts review all test results and write reports in a clear, concise, and personalized way. We also include information for research studies in specific clinical situations.
- Impactful discovery: Our researchers continue working to find answers even after testing is complete. Through both internal research efforts and global collaborations, we have identified and published hundreds of new disease-gene relationships and developed novel tools for genomic data analysis. These efforts ultimately deliver more diagnostic findings to individuals.
Learn more About Us here.
At GeneDx, we're driven by urgency and purpose: helping patients get diagnosed earlier. Our mission, to empower everyone to live their healthiest life through genomics, drives our team to make a tangible impact each day – and shapes our culture where high standards, strong teamwork, and meaningful ownership are the norm. We act with intention, support one another, and deliver work we're proud to put our names on.
Here’s what you can expect day to day:
1. Play like a champion (step up, redefine what’s possible, own it)
We bring energy, focus, and a bias for action. We step up, take initiative, and deliver on our commitments – with quality, speed, and care.
We push past the obvious. We challenge assumptions, raise the bar, and make thoughtful, decisive calls — choosing progress over perfection.
We stay curious, ask questions, and share direct feedback with respect. We adapt quickly and keep learning through collaboration and continuous improvement.
If you’re motivated by meaningful work, a fast-moving environment, and teammates who care deeply about outcomes, you’ll thrive at GeneDx.
Benefits include:
- Paid Time Off (PTO)
- Health, Dental, Vision and Life insurance
- 401k Retirement Savings Plan
- Employee Stock Purchase Plan
- Employee Discounts
- Voluntary benefits
- Programs for parents and parents-to-be
- We provide expert support for family planning, pregnancy, and postpartum care, including up to 22 weeks of fully paid parental leave (U.S.) and up to $25K annually for fertility, adoption, or surrogacy.
GeneDx is an Equal Opportunity Employer.
All privacy policy information can be found here.
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