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Colossal Biosciences

Bioinformatics Engineer

Posted Yesterday
Be an Early Applicant
In-Office or Remote
2 Locations
100K-160K Annually
Mid level
In-Office or Remote
2 Locations
100K-160K Annually
Mid level
The Bioinformatics Engineer will implement workflows, develop and optimize bioinformatics tools, and manage cloud-based applications to enhance precision medicine and genomics.
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Bioinformatics Engineer

We are seeking a talented Bioinformatics Engineer with strong programming skills to tackle challenging bioinformatics and computational biology problems. The successful candidate will work collaboratively with scientists and engineers to improve existing and building new pipelines and develop visualization tools to support the exciting opportunities in precision medicine, comparative genomics, molecular evolution, and AI.  The candidate must have some experience in bioinformatics and deploying solutions on the cloud. Preference will be given to candidates with experience in nextflow and cloud deployment experience.

This position is based out of Dallas, TX but could also be remote from within the United States. Relocation assistance is available to Dallas if desired. For remote employees, travel to Dallas up to once per quarter is required. 

Duties and Responsibilities:

  • Implements bioinformatics workflows
  • Develop new bioinformatics methods and tools
  • Optimize bioinformatics workflows to run in a cloud environment

Required Skills and Abilities:

  • Candidate must have experience in bioinformatics
  • Experience setting up and configuring bioinformatics servers ie UCSC, CellXGene, Shiny, etc
  • Ability to implement, debug, and maintain computational tools in common programming languages (Python, R, C++, and/or Java)
  • Experience with bioinformatics data (e.g., DNA-seq, RNA-seq, scRNA-seq) and using common bioinformatics tools (e.g., BWA, BEDtools, GATK, IGV)
  • Great communication skills, including research report writing, code documentation, and oral presentation, with excellent attention to detail
  • Strong understanding of computer science fundamentals, including knowledge of data structures, the ability to design efficient algorithms, and skill in writing correct, readable code.
  • Proficiency with handling large-scale genomic data in a Linux and/or cloud environment (e.g., Google Cloud)
  • Experience with version control software (e.g., Git)
  • Ability to work independently and successfully in a matrix environment, prioritize and manage multiple tasks simultaneously, integrate cross-functional issues and balance competing priorities effectively
  • Design, develop, and implement cloud-based applications and services in AWS and Azure
  • Modernize applications to leverage cloud-native capabilities and improve performance and scalability
  • Optimize cloud infrastructure for cost, performance, and security
  • Manage and deploy virtual machines, serverless computing resources, and virtual networks

Education and Experience:

  • Masters with 2 years or bachelor’s with 5+ years of bioinformatics research experience in quantitative or basic science (computational biology, bioinformatics, computational chemistry)
  • Experience with version control software (e.g., Git)
  • Experience with workflow management software such as SnakeMate and Nextflow
  • Experience with cloud computing including AWS and Google Cloud
  • Experience with Laboratory Information Management Systems (LIMS)
  • Experience writing automated functional and unit test scripts
  • Experience with team-based coding, repository, and branch management
  • Experience writing automated functional and unit test scripts

Pay Range
$100,000$160,000 USD

What Colossal Offers You:

  • Medical, dental, and vision coverage
  • Unlimited PTO and company holidays so you can rest and recharge 
  • Flexible spending accounts (FSA)
  • Company matched 401k retirement plan
  • Paid parental leave up to 12 weeks
  • Education reimbursement 
  • An opportunity to help us return the Earth to a healthier state

The team at Colossal is committed, colorful, passionate, intelligent, collaborative, creative, experienced, scientific and world-class. That sounds like a lot to fit into one building. That’s why we are spread out in several locations that include laboratories, test facilities, academic institutions, libraries and offices. 

Through it all, however, we maintain a culture of positivity, hope, happiness and belief that we’re doing something big. Something Colossal.

Colossal is proud to be an equal employment opportunity workplace. We welcome people from all backgrounds as well as celebrate and support diversity. We are committed to providing an inclusive environment of mutual respect that is free from discrimination and harassment so everyone can thrive. 

EEO is the Law 

Search Firm Representatives: Colossal does not accept unsolicited assistance from search firms. No fees will be paid for a hired candidate where no pre-existing agreement is in place. We handle most recruitment in-house. 

Colossal is proud to be named a Best Place to Work by BuiltIn for 3 years in a row across multiple categories in 2023, 2024, and 2025:

  • #1 on the 50 Best Startups to Work For in Dallas in 2023!
  • 100 Best Midsize Places to Work in Dallas in 2024 & 2025
  • 100 Best Places to Work in Dallas, TX (All Size Employers) in 2024 & 2025

Built In 2025 Award Lists

Great Place to Work Certification Page

Most Loved Workplace Certification Page - Proud to be certified as a most loved workplace including: most loved CEO, most loved workplaces for LGBTQ+, most loved workplaces for women, and most loved workplaces for young professionals.

Newsweek's Most Loved Workplaces 2024 Award List - Excited to be amongst the winners of Newsweek's 2024 Most Loved Workplaces! 

            

 

Top Skills

AWS
Azure
Bedtools
Bwa
C++
Cellxgene
Gatk
Git
GCP
Igv
Java
Linux
Python
R
Shiny
Ucsc

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