Top Remote Systems Engineer Jobs in Denver & Boulder, CO

Lead end-to-end LLM inference performance across serving systems, models, GPU hardware, and workloads. Define rigorous benchmarks, diagnose bottlenecks from scheduling through kernels and interconnects, optimize single- and multi-node deployments, and deliver production-ready runtimes and configurations. Collaborate with product and infrastructure teams, evaluate inference technologies, and implement runtime fixes. The role requires strong Python engineering, production experience with serving engines such as vLLM or SGLang, GPU profiling, and knowledge of modern inference optimization techniques.

Lead complex presales engagements for Boomi’s API Management solutions across North America. Design API-first strategies, governance models, security policies, developer portals, and enterprise architectures. Advise executive stakeholders on digital ecosystems and business value, lead proofs of concept and RFI/RFP responses, and demonstrate integration between API Management and iPaaS capabilities. The role requires deep expertise in API lifecycle management, gateways, identity and security frameworks, cloud platforms, microservices, service mesh, and event-driven architectures.

Lead systems engineering for a next-generation unmanned aircraft system. Responsibilities include defining system architecture, behaviors, requirements, interfaces, fault responses, and traceability; integrating avionics, autonomy, propulsion, sensors, and mission systems; conducting MBSE modeling, trade studies, safety analyses, flight testing, and performance validation; and coordinating cross-functional teams, DoD stakeholders, and government partners through development and operational deployment.

Build and maintain lead-to-order business systems across Salesforce and connected platforms. Design complex applications, declarative automation, Apex and Lightning solutions, integrations, APIs, data models, and security controls. Remediate technical debt, lead migrations and tool rollouts, manage testing and cutovers, and ensure production systems are observable, documented, and governed. Partner cross-functionally to translate business requirements into scalable solutions while supporting AI capabilities in go-to-market workflows.

Architects, scales, and governs design systems, ensuring 1:1 parity between design assets and front-end code. Owns component libraries, design documentation, design tokens, accessibility standards, and UI pattern governance. Partners closely with development, product, and UX teams to guide implementation, manage component requests, conduct usability testing, reduce technical debt, and improve developer experience. Also maintains machine-readable documentation and AI-ready design infrastructure.

Own and improve Onebrief’s corporate security stack across endpoints, identity, SaaS, browsers, Zero Trust, EDR, SIEM, and MDM. Establish secure configuration baselines, detect and remediate drift, integrate telemetry, and build API-driven or infrastructure-as-code automation. Translate CMMC 2.0 and NIST-aligned requirements into continuously validated technical controls and reliable audit evidence. Partner with Corporate IT, Security Operations, GRC, and application owners to strengthen security posture and reduce manual compliance work.

Supports the IHS Electronic Health Records Modernization program by designing, integrating, installing, configuring, testing, and maintaining biomedical and end-user devices. Develops solutions for complex device engineering, infrastructure, security, backup, and redundancy challenges; maintains technical documentation; collaborates with cyber and implementation teams; and may lead or mentor others. The role is fully remote, requires Oracle Health experience, and may involve up to 25% travel.

Leads systems engineering for a large-scale air surveillance and air defense communications system. Manages technical baselines, integration, modernization, testing, compliance, configuration control, architecture evaluations, and technical documentation. Coordinates software, hardware, networking, radar, field service, program management, and military stakeholders. Supports weapon-system interoperability, live and simulated exercises, operational training, and technical briefings for U.S. and partner leadership across Europe.

Designs, develops, deploys, administers, and sustains MuleSoft Anypoint Platform and/or Informatica integrations in AWS GovCloud. Builds secure REST APIs and Mule applications, manages API gateways and lifecycle governance, implements authentication, monitoring, CI/CD, and data synchronization, and integrates Navy logistics and mission-partner systems. The role also performs testing, documentation, incident triage, performance tuning, RMF/STIG support, stakeholder coordination, and knowledge transfer.

Lead architecture, integration, deployment, security, and sustainment of the Informatica Data Governance Suite in AWS GovCloud. Design highly available and recoverable infrastructure, implement Infrastructure as Code and CI/CD, establish security and compliance controls, coordinate multidisciplinary engineering work, oversee testing and monitoring, manage technical risks, and transfer operational knowledge to NAVSUP personnel.

Leads solution architecture and engineering for a MuleSoft Anypoint Platform implementation in AWS GovCloud. Designs highly available, secure, recoverable infrastructure; establishes Infrastructure as Code, DevSecOps, CI/CD, monitoring, and configuration standards; guides API and data integration; and coordinates RMF/ATO, STIG compliance, testing, risk management, deployment, documentation, and production sustainment. Provides technical leadership, stakeholder coordination, Government briefings, and knowledge transfer to Navy personnel.

Implements, configures, deploys, and supports software platforms and HL7 interfaces. Troubleshoots operating systems, databases, VPN connectivity, and application integrations; manages customer support tickets, SLAs, documentation, and implementation timelines. Advises customers on technical requirements, collaborates across teams to improve reliability, and participates in an on-call rotation.

Design and build production AI applications for enterprise clients, including data processing, retrieval, APIs, tools, integrations, evaluations, and deployment. Partner with client experts to improve system performance and reliability, support cloud, CI/CD, security, and operational processes, and communicate technical tradeoffs clearly. The role also involves automating internal workflows and helping clients adopt new AI-enabled ways of working.

Designs, implements, manages, and tests technical infrastructure and systems solutions. Gathers and translates business requirements, develops architectural documentation and standards, coordinates vendors, reviews technical work, mentors engineers, troubleshoots complex systems, and ensures compliance with risk, regulatory, audit, and internal control requirements. The role also maintains expertise in banking applications, supported technologies, and industry best practices.

Own and evolve Jira, Aha!, and related product and engineering platforms. Configure workflows, permissions, schemas, dashboards, automations, integrations, and reporting while improving governance, data quality, reliability, and adoption. Partner with Product, Engineering, TPM, Finance, and IT teams to translate business needs into scalable systems. Lead implementations, migrations, platform lifecycle management, troubleshooting, documentation, training, and tooling evaluations.

Supports internal and customer infrastructure platforms through incident triage, systems administration, cloud provisioning, Kubernetes deployments, identity management, monitoring, security hygiene, and runbook execution. The role requires Linux, networking, scripting, Git, cloud, container, and SaaS administration skills, with opportunities to grow into environment builds, configuration changes, compliance work, and platform ownership. It is fully remote, U.S.-based, and supports government-related environments requiring Secret clearance eligibility.

Leads enterprise systems architecture, administration, optimization, troubleshooting, upgrades, and outage response across servers, networks, virtualization, storage, databases, cloud services, and Microsoft 365. Provides technical leadership, supports security baselines, contributes to IT strategy and budgeting, manages projects, and collaborates with vendors and cross-functional teams. Uses and evaluates AI-assisted tools for coding, testing, troubleshooting, documentation, and research while validating outputs for security, privacy, and quality. Occasional business travel may be required.

Own the configuration, administration, data quality, routing, integrations, imports, and operational health of Salesforce and HubSpot for revenue teams. Manage lead and account assignment, HubSpot-Salesforce data flows, audits, bulk updates, issue triage, testing, change management, and documentation. Partner with Sales, Marketing, Customer Success, and Support while communicating system changes and resolving platform issues within defined SLAs.

Provide pre-sales technical leadership, solution design, demonstrations, proofs of concept, and deployment support for enterprise wired and wireless networking solutions. Design secure Wi-Fi, switching, routing, cloud-managed, and Zero Trust environments. Support post-sales escalations, channel partners, and customer success while relaying technical feedback to Product Management. Conduct RF planning, deliver technical training, and maintain expertise in enterprise networking trends and competitive products.

Designs, builds, and operates scalable machine learning platforms, pipelines, and infrastructure for model training, deployment, serving, and monitoring. Develops MLOps tooling, CI/CD workflows, model registries, feature stores, and experiment tracking. Ensures production reliability, observability, security, compliance, and cost efficiency across ML systems. Collaborates with product and engineering teams, integrates platforms with existing systems and data sources, and mentors engineers on reusable ML platform practices.

Lead systems engineering for a next-generation autonomous UAS, including system architecture, requirements decomposition, behavior modeling, avionics and autonomy integration, safety analysis, trade studies, flight testing, and performance validation. Collaborate with hardware, software, propulsion, manufacturing, flight operations, DoD stakeholders, and government agencies to develop a mission-ready aircraft from clean sheet through first flight and deployment.

Develop and support Oracle-based enterprise financial, billing, and revenue management solutions. Design OIC integrations connecting Oracle Fusion applications with external systems, configure ORMB modules, build middleware components, optimize performance, troubleshoot issues, and support upgrades. Collaborate with technology, finance, infrastructure, and operations teams while ensuring secure, compliant data exchange and maintaining technical documentation.

Design, build, monitor, and maintain large-scale Linux infrastructure supporting distributed S3-compatible object storage across multi-cloud environments. Responsibilities include kernel and storage optimization, network and hardware troubleshooting, automation with Chef or Ansible, observability, forecasting capacity, technical leadership, project coordination, mentoring, documentation, and on-call support.

Designs, develops, integrates, and maintains complex telecommunications and unified communications systems for the FAA. Serves as an Avaya Aura and OSSI subject matter expert, creating automation scripting frameworks and supporting system databases and interfaces. Responsibilities include systems lifecycle engineering, configuration, testing, documentation, training, technical guidance, and cloud deployments using platforms including Avaya, Juniper, Cisco, Zoom, and Microsoft products.

Summer internship to build production-facing realtime intelligence for a mobile app that optimizes campus quest participation. Design context-aware quest logic, detect stalls/drop-offs, suggest micro-actions, instrument evaluation loops, and ship components on top of existing realtime systems to improve behavioral outcomes like IRL quest completion and retention.