Top Remote Systems Engineer Jobs in Denver & Boulder, CO

Lead end-to-end LLM inference performance across serving systems, models, GPU hardware, and workloads. Define rigorous benchmarks, diagnose bottlenecks from scheduling through kernels and interconnects, optimize single- and multi-node deployments, and deliver production-ready runtimes and configurations. Collaborate with product and infrastructure teams, evaluate inference technologies, and implement runtime fixes. The role requires strong Python engineering, production experience with serving engines such as vLLM or SGLang, GPU profiling, and knowledge of modern inference optimization techniques.

Lead complex presales engagements for Boomi’s API Management solutions across North America. Design API-first strategies, governance models, security policies, developer portals, and enterprise architectures. Advise executive stakeholders on digital ecosystems and business value, lead proofs of concept and RFI/RFP responses, and demonstrate integration between API Management and iPaaS capabilities. The role requires deep expertise in API lifecycle management, gateways, identity and security frameworks, cloud platforms, microservices, service mesh, and event-driven architectures.

Lead systems engineering for a next-generation unmanned aircraft system. Responsibilities include defining system architecture, behaviors, requirements, interfaces, fault responses, and traceability; integrating avionics, autonomy, propulsion, sensors, and mission systems; conducting MBSE modeling, trade studies, safety analyses, flight testing, and performance validation; and coordinating cross-functional teams, DoD stakeholders, and government partners through development and operational deployment.

Build and lead development of full-stack agentic AI products for systems modernization. Responsibilities include creating coding harnesses and runtime layers, integrating source control, CI/CD, security, and developer tools, scaling coding-agent workflows, and partnering with customers, designers, and mission teams. The role requires production-grade, cybersecurity-compliant systems, strong product judgment, and close collaboration with forward-deployed engineering teams supporting national security missions.

Secure Runpod’s multitenant GPU cloud infrastructure across bare-metal and virtualized environments. Responsibilities include designing workload and network isolation, hardening Linux kernels and container platforms, testing hypervisor and hardware security, developing low-level controls in C, Go, or Rust, securing GPU and PCIe interactions, and responding to infrastructure security incidents with forensic capabilities for ephemeral containers.

Develop and govern Cameo-based SysML models for space and missile defense systems. Lead requirements traceability, architecture, interfaces, verification and validation modeling, model integration, and digital thread development. Support systems engineering processes, DoD compliance, Agile model delivery, classified programs, subcontractor evaluation, customer engagements, and proposal activities. Integrate MBSE models with PLM and enterprise data systems while mentoring teams and driving MBSE adoption.

Develop and maintain internal full-stack applications using C#/Blazor or Python. Build CI/CD pipelines and infrastructure automation with GitLab, Azure DevOps, GitHub, Artifactory, and SonarQube. Partner with cross-functional teams to improve software delivery, code quality, security, compliance, and operational visibility. Implement scalable enterprise solutions, infrastructure as code, secure development practices, and DevSecOps workflows.

Lead the architecture, development, customization, and integration of NetSuite finance systems supporting accounting, Order-to-Cash, and Record-to-Report processes. Partner with Finance, Accounting, Tax, Treasury, Audit, and Data Engineering teams to implement controls, improve close processes, enhance reporting, ensure SOX and GAAP compliance, and manage integrations. Establish NetSuite engineering standards, mentor engineers, oversee data governance, and provide technical leadership for scalable finance technology solutions.

Deploy, upgrade, and maintain High-Speed Data infrastructure (DNS, DHCP, DOCSIS). Administer CentOS/RHEL systems, automate with Python/Ansible/Shell, troubleshoot escalations, create LLDs, run upgrades, train teams, perform on-call duties, and ensure security and high availability.

Supports enterprise platforms and applications by administering secure systems, monitoring and maintaining Tier-2/Tier-3 environments, analyzing data, performing network upgrades, and documenting system architectures. Designs, deploys, and maintains AWS and hybrid-cloud systems while administering Linux and Windows environments in large enterprises. Collaborates with engineers, developers, and testers to meet program needs and maintain security standards.

Design and build modular, high-performance distributed systems for AI model inference. Lead architecture decisions involving concurrency, data movement, APIs, system boundaries, and reliability. Develop extensible interfaces and composable components for model developers and contributors. Diagnose complex performance bottlenecks and support production software. The role values systems programming, abstraction design, GPU and accelerator optimization, inference frameworks, and research awareness.

Build and maintain lead-to-order business systems across Salesforce and connected platforms. Design complex applications, declarative automation, Apex and Lightning solutions, integrations, APIs, data models, and security controls. Remediate technical debt, lead migrations and tool rollouts, manage testing and cutovers, and ensure production systems are observable, documented, and governed. Partner cross-functionally to translate business requirements into scalable solutions while supporting AI capabilities in go-to-market workflows.

Own the reliability, availability, performance, observability, and security of Ophelia’s GCP telehealth platform. Define SLOs, improve monitoring and incident response, expand Terraform infrastructure, strengthen CI/CD, manage disaster recovery, and address latency and Cloud Run performance. Lead on-call maturity, HIPAA/SOC 2 infrastructure controls, and reliability education for engineers. Use AI-assisted tools for automation and incident triage while partnering with technical and non-technical stakeholders.

Senior Systems Engineer responsible for designing, deploying, maintaining, and modernizing DHA Application Lifecycle Management tools across secure military health networks. The role integrates AI/ML and LLM capabilities into DevSecOps pipelines, ensures RMF, STIG, HIPAA, and ATO compliance, evaluates architectures and integrations, manages technical risks and lifecycle roadmaps, supports testing and deployments, and provides engineering documentation, incident support, training, and stakeholder guidance.

Design and build advanced applications, integrate external APIs, and contribute to large open-source codebases for global clients. The role requires strong systems programming, networking, memory management, concurrency, operating-system concepts, data modeling, parallelism, API design, and technical documentation skills. Candidates should learn quickly, take ownership, navigate unfamiliar codebases, identify edge cases, and continuously improve through feedback. The process includes a technical assessment, interview, and OSS hackweek.

Architects, scales, and governs design systems, ensuring 1:1 parity between design assets and front-end code. Owns component libraries, design documentation, design tokens, accessibility standards, and UI pattern governance. Partners closely with development, product, and UX teams to guide implementation, manage component requests, conduct usability testing, reduce technical debt, and improve developer experience. Also maintains machine-readable documentation and AI-ready design infrastructure.

Leads complex power generation control systems projects, including planning, scheduling, design, programming, and implementation of hardware and software solutions. Focuses on turbine controls, instrumentation, electrical systems, and DCS/PLC integration. Contributes to proposals, technical scopes, estimates, and resource planning while coordinating with clients, contractors, and internal teams. The role is remote or hybrid and requires approximately 15–30% domestic and local travel.

Maintains client systems and infrastructure by managing user accounts, access permissions, servers, software installations, security patches, backups, and preventative maintenance. Monitors server performance, resolves connectivity issues, supports hardware installations, educates users, and escalates complex technical problems. The role combines systems administration, infrastructure support, troubleshooting, documentation, and customer service in a remote U.S. environment.

Leads power system studies and grid interconnection projects for utility-scale solar PV and battery storage systems. Performs short-circuit, arc-flash, load-flow, grounding, harmonic, ampacity, and power-quality analyses; designs collection systems; specifies equipment; prepares reports and presentations; manages project scope, schedules, and budgets; supports clients; and mentors junior engineers.

Maintains client infrastructure through user account and permissions management, server monitoring, software installation, security patching, backups, preventative maintenance, and connectivity troubleshooting. Provides remote technical support, trains users, performs minor equipment repairs, documents solutions, escalates complex issues, and builds strong customer relationships. The role supports systems administration and infrastructure operations while developing the engineer’s technical and customer-service capabilities.

Maintains client systems and infrastructure by managing accounts and permissions, monitoring servers, applying patches, installing software, conducting backups, resolving connectivity issues, and providing user support. The role also includes preventative maintenance, minor equipment repairs, technical escalation, documentation, and customer communication. It offers foundational systems administration experience with opportunities to develop through training, certifications, and increasingly complex assignments.

Leads technical pre-sales activities for cyber resilience and disaster recovery solutions. Partners with sales teams, account managers, and channel partners to understand customer needs, design architectures, conduct evaluations and proof-of-concepts, configure systems, respond to RFPs, and deliver technical presentations. Builds customer-specific solutions, validates interoperability and performance, positions offerings against competitors, and supports opportunities through technical close and revenue growth.

Lead the development of Benchmark’s spacecraft systems engineering function. Establish engineering practices, own system-level trades, requirements, verification planning, interface documentation, and spacecraft budgets. Evaluate COTS components, assess qualification evidence, coordinate cross-functional technical needs, and support spacecraft integration, testing, and delivery. Build and mentor the systems engineering team while driving technical rigor across spacecraft programs.

Summer internship to build production-facing realtime intelligence for a mobile app that optimizes campus quest participation. Design context-aware quest logic, detect stalls/drop-offs, suggest micro-actions, instrument evaluation loops, and ship components on top of existing realtime systems to improve behavioral outcomes like IRL quest completion and retention.

Administer and secure identity, email, network, firewall, and collaboration infrastructure for a distributed workforce. Responsibilities include Okta or equivalent SSO management, email security controls, incident response, network administration, routing, switching, VPNs, firewall policies, documentation, vendor management, and infrastructure improvement. The role partners with Security and Help Desk teams, troubleshoots complex issues, supports onboarding and offboarding, and manages moderately complex projects independently.