Top Remote Senior Level Machine Learning Engineer Jobs in CO

Build, deploy, and maintain AI-powered agents, APIs, and applications for People operations on Snowflake. Turn messy business requirements into production systems, integrate with Workday/Notion/case tools, ensure data governance and security, design multi-model LLM reliability controls, and operate full lifecycle including CI/CD, monitoring, and incident fixes while partnering with non-technical stakeholders.

Design, develop, and deploy machine learning models and pipelines to optimize operations. Lead full ML project lifecycle, ensure model evaluation/monitoring, collaborate cross-functionally, mentor junior engineers, and drive continuous improvement in ML applications and processes.

Lead advanced analytics and ML efforts to extract insights from large-scale historical data, design features and data representations for models and LLM/agentic systems, partner with product and engineering to build data pipelines and prototypes, evaluate AI workflows, and drive innovation through experiments and empirical analysis to inform product strategy.

Build and operate Coinbase's LLM and agent platform: unified model gateway, AI Hub, secure microVM agent runtime, knowledge base integrations, AI FinOps, observability and evaluation tooling, and production-grade agent deployments with teams across the company.

Leads and manages an applied machine learning team developing fraud detection and identity verification models. Responsibilities include people management, coaching, code review, production ML systems, model lifecycle ownership, experimentation, deployment, monitoring, fraud research, cross-functional prioritization, and communicating results. The role remains hands-on while partnering with Product, Engineering, Risk, and leadership to drive measurable business impact and shape future product strategy using machine learning and AI.

Design and deploy machine learning models for financial document processing, optimize large language models, collaborate with cross-functional teams, and guide junior peers in a fast-paced environment.

Lead complex modeling projects combining deep learning, LLMs, and traditional techniques. Prototype, deploy, and monitor production models, mentor data scientists, collaborate with engineering/product, and translate results into business impact for insurance customers.

Lead and deliver productionized ML solutions across audience, marketing, pharma direct, and employer analytics. Design segmentation, propensity, attribution, and identity models; apply causal inference and experimentation; operationalize models with MLOps; evaluate generative AI/LLM use cases; set technical roadmap and mentor data scientists to drive measurable business impact.

Take Deepgram's speech models and optimize, compile, and run them on resource-constrained embedded and edge hardware. Work across model compression, runtime performance (C/C++/Rust), RTOS/bare-metal and embedded Linux environments, vendor NPUs/DSPs and inference runtimes, benchmarking, deployment pipelines, OTA updates, and partner with silicon vendors to enable real-time, low-power on-device voice experiences.

Research, design, and implement discrete optimization and mission-planning algorithms for multi-agent autonomous systems; improve and maintain C++ mission-planning software; define technical roadmaps; mentor engineers; perform full software and hardware-in-the-loop simulations.