Top Remote Senior Level Machine Learning Engineer Jobs in CO

Build and operate Coinbase's LLM and agent platform: unified model gateway, AI Hub, secure microVM agent runtime, knowledge base integrations, AI FinOps, observability and evaluation tooling, and production-grade agent deployments with teams across the company.

Lead design, development, and deployment of production-grade, large-scale ML systems. Influence ML strategy, integrate models with platform and data infrastructure, mentor engineers, communicate results to stakeholders, and mature ML infrastructure and abstractions across teams.

The Senior Machine Learning Engineer will design, implement, and optimize machine learning models, drive AI initiatives, and collaborate cross-functionally to enhance SailPoint's AI capabilities.

Lead the development of fraud prediction models using machine learning, collaborating across teams to build, scale, and monitor models in production.

Take Deepgram's speech models and optimize, compile, and run them on resource-constrained embedded and edge hardware. Work across model compression, runtime performance (C/C++/Rust), RTOS/bare-metal and embedded Linux environments, vendor NPUs/DSPs and inference runtimes, benchmarking, deployment pipelines, OTA updates, and partner with silicon vendors to enable real-time, low-power on-device voice experiences.

Develop scalable machine learning services for data enrichment, managing the ML lifecycle from model training to deployment, and ensuring performance and reliability standards.

As a Staff Machine Learning Engineer, you will design AI products on Edge devices, optimize ML model performance, and work with large-scale datasets, collaborating across teams to deliver impactful solutions.

Build and productionize agentic workflows and RAG pipelines, integrate LLMs into the GTM stack, and develop high-performance backend services and ML pipelines. Connect quoting engine, Salesforce, and data lakes, solve synchronization and architectural challenges, and ensure observability, scalability, and reliability for sales automation tools.

The Staff Machine Learning Engineer will lead ML initiatives, develop ML systems, collaborate with cross-functional teams, and mentor junior engineers to optimize healthcare intake workflows using advanced machine learning techniques.

Lead design and delivery of low-latency market-making and automated trading strategies. Translate quantitative research into production systems, build backtesting and real-time decision engines, ensure scalability and observability, manage risk-aware optimization, and influence cross-functional teams on strategy and technical direction.