Top Remote Senior Level Machine Learning Engineer Jobs in CO

Take Deepgram's speech models and optimize, compile, and run them on resource-constrained embedded and edge hardware. Work across model compression, runtime performance (C/C++/Rust), RTOS/bare-metal and embedded Linux environments, vendor NPUs/DSPs and inference runtimes, benchmarking, deployment pipelines, OTA updates, and partner with silicon vendors to enable real-time, low-power on-device voice experiences.

Develop scalable machine learning services for data enrichment, managing the ML lifecycle from model training to deployment, and ensuring performance and reliability standards.

The Principal ML Engineer at Agero will develop and productionize a Dispatch System using ML models, optimize decision-making processes, and lead a team to improve operational performance.

Build and operate Coinbase's LLM and agent platform: unified model gateway, AI Hub, secure microVM agent runtime, knowledge base integrations, AI FinOps, observability and evaluation tooling, and production-grade agent deployments with teams across the company.

As a Senior Staff Machine Learning Engineer at Affirm, you will lead complex ML system design and implementation, mentor engineers, and drive innovative ML strategies for financial services.

As a Staff Machine Learning Engineer, you will design AI products on Edge devices, optimize ML model performance, and work with large-scale datasets, collaborating across teams to deliver impactful solutions.

Build and productionize agentic workflows and RAG pipelines, integrate LLMs into the GTM stack, and develop high-performance backend services and ML pipelines. Connect quoting engine, Salesforce, and data lakes, solve synchronization and architectural challenges, and ensure observability, scalability, and reliability for sales automation tools.

The Staff Machine Learning Engineer will lead ML initiatives, develop ML systems, collaborate with cross-functional teams, and mentor junior engineers to optimize healthcare intake workflows using advanced machine learning techniques.

Lead design and delivery of low-latency market-making and automated trading strategies. Translate quantitative research into production systems, build backtesting and real-time decision engines, ensure scalability and observability, manage risk-aware optimization, and influence cross-functional teams on strategy and technical direction.

The Staff Machine Learning Engineer will design and build scalable ML systems, mentor engineers, and drive AI strategy at SailPoint, focusing on AI-powered identity security solutions.