Vice President, Commercial Pipeline

Crinetics is a pharmaceutical company based in San Diego, California, developing much-needed therapies for people with endocrine diseases and endocrine-related tumors. We were founded by a dedicated team of scientists with the simple belief that better therapies developed from rigorous innovation can lead to better lives. Our work continues to make a real difference in the lives of patients. We have a prolific discovery engine and a robust preclinical and clinical development pipeline. We are driven by science with a patient-centric and team-oriented culture. Crinetics is known for its inclusive workplace culture. We are also a dog-friendly workplace. This is an exciting time to join Crinetics as we shape our organization into the world’s premier fully integrated endocrine company from discovery to patients. Join our team as we transform the lives of others.

Position Summary:

The Vice President, Commercial Pipeline will report directly to the Chief Commercial Officer. This role is responsible for developing and leading the global and U.S. marketing strategy for all Crinetics programs that are post‑Phase 1 in clinical development. This leader will define early commercialization pathways, build disease‑area and asset‑level strategies, and ensure seamless progression from clinical development to launch readiness. This role will partner closely with R&D, Clinical Development, Medical Affairs, and Commercial to shape market positioning, inform lifecycle planning, and prepare the organization for future product launches.

This role requires a strategic, enterprise‑minded leader who thrives in a science‑driven, fast‑growing organization and who can translate complex clinical and scientific insights into impactful marketing strategies that drive value across Crinetics’ advancing pipeline.

Essential Job Functions and Responsibilities:

These may include but are not limited to:

• Key member of the commercial leadership team contributing to pipeline strategy, prioritization, and long‑range planning.
• Lead the development of integrated global and U.S. marketing strategies for all programs entering and progressing through Phase 2 and Phase 3 clinical development.
• Build a robust forecasting and market assessment framework to enable data‑driven decision‑making and commercial readiness.
• Partner cross‑functionally to incorporate market insights, competitive intelligence, patient needs, and clinical data into asset strategies.
• Identify and translate physician, patient, and stakeholder insights into actionable marketing approaches.
• Partner with GPLs to build commercial road map.
• Lead commercial sub-teams for pipeline programs.
• Shape early brand positioning, value proposition, messaging platforms, and disease education strategies.
• Develop commercial launch roadmaps and ensure alignment with clinical, regulatory, and medical functions.
• Oversee pre‑launch activities including disease awareness, stakeholder mapping, early expert engagement, and payer insight development prior to transition to marketing team.
• Serve as the commercial voice in clinical development planning, including protocol design and target product profile evolution.
• Establish and manage relationships with external agencies, consultants, and key partners.
• Manage departmental budget and ensure effective resource allocation.
• Present pipeline marketing strategies, forecasts, and recommendations to Senior Leadership and the Board of Directors.
• Drive operational processes and communication pathways across marketing, commercial, and R&D teams.
• Prepare for indication expansions and future lifecycle management opportunities across multiple therapeutic areas.
• Other duties as assigned.

Education and Experience:

Required:

• Bachelor’s degree required in a business‑related, marketing, or life sciences field (advanced degree preferred).
• A minimum of 15+ years of pharmaceutical or biotechnology commercial experience with at least 6 years in pipeline/early‑phase marketing, new product planning, commercial strategy, or related roles.
• At least 14 years of experience leading, building, and developing teams.
• Proven success developing marketing strategies for clinical‑stage assets, ideally in rare diseases, endocrinology, or adjacent therapeutic areas.
• Strong understanding of clinical development processes, regulatory considerations, and evidence‑generation strategies.
• Demonstrated ability to integrate scientific, clinical, and market inputs to guide asset strategy.
• Experience partnering with cross‑functional teams including Clinical Development, Medical Affairs, Regulatory, Market Access, and Commercial.
• Exceptional strategic thinking with the ability to lead through ambiguity and fast‑paced growth.
• Strong leadership acumen with proven ability to influence without authority.
• Demonstrated success working with patient communities, advocacy partners, and KOLs.
• Familiarity with digital and innovative marketing channels.

Physical Demands and Work Environment:

Physical Activities: On a continuous basis, sit at desk for a long period of time; intermittently answer telephone and write or use a keyboard to communicate through written means. Some walking and lifting up to 25 lbs. may be required. The noise level in the work environment is typically low to moderate. The physical demands described above are representative of those that must be met by an employee to successfully perform the essential functions and responsibilities of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions and responsibilities.

Laboratory Activities (if applicable): Biology and chemical laboratory environment experience needed. Environmental health and safety requirements also apply.

Travel:

You may be required to travel for up to 30% of your time.

Equal Opportunity Employer:

Crinetics is proud to be an Equal Opportunity Employer. We provide equal employment opportunities to all employees and employment applicants without regard to unlawful considerations of sex, sexual orientation, gender (including gender identity and/or expression), pregnancy, race, color, creed, national or ethnic origin, citizenship status, religion or similar philosophical beliefs, disability, marital and civil union status, age, genetic information, veteran status or any personal attribute or characteristic that is protected by applicable local, state or federal laws.

Salary Range

In addition to your base pay, our total rewards program consists of a discretionary annual target bonus, stock options, ESPP, and 401k match. We also provide top-notch health insurance plans for employees (and their families) to include medical, dental, vision and basic life insurance, 20 days of PTO, 10 paid holidays, and a winter company shutdown.