At Caris, we understand that cancer is an ugly word—a word no one wants to hear, but one that connects us all. That’s why we’re not just transforming cancer care—we’re changing lives.
We introduced precision medicine to the world and built an industry around the idea that every patient deserves answers as unique as their DNA. Backed by cutting-edge molecular science and AI, we ask ourselves every day: “What would I do if this patient were my mom?” That question drives everything we do.
But our mission doesn’t stop with cancer. We're pushing the frontiers of medicine and leading a revolution in healthcare—driven by innovation, compassion, and purpose.
Join us in our mission to improve the human condition across multiple diseases. If you're passionate about meaningful work and want to be part of something bigger than yourself, Caris is where your impact begins.
Position Summary
Serve as a Staff DevOps Engineer specializing in AWS and Kubernetes to design, implement, and optimize scalable, secure cloud-native infrastructure. Lead PoC initiatives, oversee monitoring solutions, and translate SOX compliance into actionable cloud implementation plans. Break down silos by building a comprehensive team knowledge base, ensuring broad support capabilities. Provide technical leadership in cloud migration, security, and DevOps best practices, driving innovation and operational excellence across the organization.
Job Responsibilities
Lead the design, implementation, and management of Kubernetes clusters on AWS EKS, ensuring high availability, scalability, and security. Implement and manage advanced features including autoscaling, monitoring, logging, and security policies.
Spearhead proof-of-concept (PoC) initiatives for new tools and environments, evaluating their potential benefits for the organization.
Manage the full lifecycle of Kubernetes clusters, including regular upgrades, patch management, version control, and performance optimization.
Provide expert-level support and guidance to teams for deploying and optimizing applications on Kubernetes, including container orchestration and service mesh implementation.
Design and implement monitoring and alerting solutions for applications and infrastructure using CloudWatch, Prometheus, and Datadog.
Develop observability standards and dashboards, leveraging AI/AIOps approaches and SRE agents to enable anomaly detection, alert noise reduction, and automated root cause analysis.
Develop and maintain Infrastructure as Code (IaC) using tools such as Terraform or AWS CDK, and implement CI/CD pipelines for efficient application deployment and image management.
Design and implement security solutions, including the deployment and management of security tools, and translate SOX compliance requirements into actionable implementation plans for cloud environments.
Lead initiatives for cloud migration and modernization of legacy applications, collaborating with cross-functional teams to support their cloud and infrastructure needs.
Provide technical leadership and mentorship to junior engineers on cloud technologies and DevOps practices, implementing knowledge-sharing initiatives to ensure broad support capabilities across the team.
Stay current with emerging AWS services and features, evaluating their potential benefits and optimizing cloud resource utilization and cost-efficiency.
Develop and maintain comprehensive documentation, including a team knowledge base, runbooks, and process documentation to eliminate information silos.
Proactively identify areas of inefficiency and develop strategic plans for process improvements across the DevOps and cloud infrastructure landscape.
Participate in on-call rotations to support critical cloud infrastructure and respond to emergency issues as needed.
Required Qualifications
Bachelor's degree in Computer Science, Information Technology, or related field.
7+ years of experience in DevOps or Site Reliability Engineering roles.
5+ years of hands-on experience with AWS services and cloud architecture.
5+ years of hands-on experience with Kubernetes, including deep expertise in cluster management, troubleshooting, and optimization.
Strong proficiency in at least one programming language (e.g., Python, Go, Java).
Extensive experience with Infrastructure as Code tools (e.g., Terraform, CloudFormation, AWS CDK).
Deep understanding of containerization technologies (Docker) and orchestration platforms (Kubernetes) including security best practices.
Experience with CI/CD tools and methodologies, particularly GitLab CI and Github actions.
Strong knowledge of networking concepts and implementation in cloud environments.
Excellent problem-solving skills and ability to troubleshoot complex systems.
Proven ability to lead PoC initiatives and evaluate new technologies.
Demonstrated experience in creating and maintaining technical documentation and knowledge bases.
Demonstrated ability to identify operational inefficiencies and develop strategic plans for process improvements in complex cloud and DevOps environments.
Strong analytical skills with the ability to translate technical insights into actionable business recommendations.
Strong communication and mentoring skills, with the ability to effectively transfer knowledge to team members of varying experience levels.
Proficient in Microsoft Office Suite, specifically Word, Excel, Outlook, and general working knowledge of Internet for business use.
Preferred Qualifications
AWS Professional level certifications (e.g., Solutions Architect Professional, DevOps Engineer Professional).
Kubernetes certifications (e.g., CKA, CKAD, CKS).
Experience with multiple cloud platforms (e.g., AWS, GCP) for multi-cloud architectures.
Knowledge of database technologies, including MySQL, PostgreSQL, and DynamoDB.
Proficiency with specific monitoring and observability tools such as Prometheus, Grafana, and ELK stack.
Familiarity with serverless architectures and microservices.
Hands-on experience with configuration management tools (e.g., Ansible, Chef, Puppet).
Experience in implementing knowledge management systems or tools in a DevOps environment.
Contributions to open-source projects or personal projects demonstrating cloud expertise.
Physical Demands
Ability to sit for extended periods while working on a computer.
Training
All job specific, safety, and compliance training are assigned based on the job functions associated with this employee.
Other
This position may require periodic travel and some evenings, weekends and/or holidays.
Job may require after-hours response to emergency issues and on-call availability as required.
Willingness to pursue ongoing professional development and stay current with emerging technologies in the field.
Job responsibilities may be modified or expanded at the discretion of management to meet changing business needs and organizational requirements.
Annual Hiring Range
$140,000 - $179,000
Actual compensation offer to candidate may vary from posted hiring range based upon geographic location, work experience, education, and/or skill level. The pay ratio between base pay and target incentive (if applicable) will be finalized at offer.
Description of Benefits
- Highly competitive and inclusive medical, dental and vision coverage options
- Health Savings Account for medical expenses and dependent care expenses
- Flexible Spending Account to pay for certain out-of-pocket expenses
- Paid time off, including: vacation, sick time and holidays
- 401k match and Financial Planning tools
- LTD and STD insurance coverages, as well as voluntary benefit options
- Employee Assistance Program
- Pet Insurance
- Legal Assistance
- Tuition Assistance
Conditions of Employment: Individual must successfully complete pre-employment process.
This job description reflects management’s assignment of essential functions. Nothing in this job description restricts management’s right to assign or reassign duties and responsibilities to this job at any time.
Caris Life Sciences is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, gender, gender identity, sexual orientation, age, status as a protected veteran, among other things, or status as a qualified individual with disability.
Top Skills
Similar Jobs
What you need to know about the Colorado Tech Scene
Key Facts About Colorado Tech
- Number of Tech Workers: 260,000; 8.5% of overall workforce (2024 CompTIA survey)
- Major Tech Employers: Lockheed Martin, Century Link, Comcast, BAE Systems, Level 3
- Key Industries: Software, artificial intelligence, aerospace, e-commerce, fintech, healthtech
- Funding Landscape: $4.9 billion in VC funding in 2024 (Pitchbook)
- Notable Investors: Access Venture Partners, Ridgeline Ventures, Techstars, Blackhorn Ventures
- Research Centers and Universities: Colorado School of Mines, University of Colorado Boulder, University of Denver, Colorado State University, Mesa Laboratory, Space Science Institute, National Center for Atmospheric Research, National Renewable Energy Laboratory, Gottlieb Institute


