Staff Accountant

Based in South San Francisco, Mission Bio is the leader in single cell multi omics solutions for precision medicine. Our mission is to empower researchers and clinicians to eradicate cancer, and our Tapestri® Platform is at the center of that effort. As the industry’s first high throughput single cell multi omics solution, Tapestri is trusted by leading academic medical centers, cancer institutes, and biopharma companies to advance research and accelerate the development of curative therapies, including the future of cell and gene therapy.

Following a successful equity financing round led by Ally Bridge Group, we are entering an exciting growth phase focused on innovation, deeper commercial partnerships, and broader clinical adoption. Our expanded tri omics capabilities now combine targeted gene expression and genotyping in a single assay, opening up new opportunities across oncology and therapeutic development.

We are a dynamic and diverse team that lives by the culture of One Cell. One Team. One Vision. We are collaborative, driven, and deeply curious. These values fuel our innovation and unite us in our mission.

This is a high-impact opportunity to join our Finance team during a pivotal time of growth. As a Staff Accountant, you’ll play a key role in strengthening our financial foundation through supporting month-end close, reconciling accounts, and ensuring the accuracy and integrity of our financial data. Your work will directly contribute to the transparency and efficiency that enable our teams to make informed, strategic decisions.

If you’re a detail-oriented, mission-driven accounting professional ready to grow your career in a cutting-edge biotech company shaping the future of precision medicine, we’d love to hear from you.

You’ll play a vital part in supporting the financial health of our organization through a wide range of accounting responsibilities including accounts payable, receivables, payroll, and monthly close activities. This position is ideal for someone who enjoys both detail-oriented work and cross-functional collaboration.

You’ll work closely with teams across the company to ensure accurate reporting, maintain compliance, and help build scalable financial processes as we continue to grow. This is an excellent opportunity to deepen your accounting expertise within a fast-paced, mission-driven environment.

Accounts Payable (AP)

• • Review, code, and process vendor invoices accurately and in a timely manner using NetSuite.
  • Ensure appropriate approval workflows and compliance with company policies.
  • Prepare bi-monthly check runs, ACH payments, and credit card reconciliations.
  • Maintain vendor records, respond to inquiries, and resolve discrepancies.
  • Manage the AP inbox and act as a liaison for vendor billing questions.
  • Prepare annual 1099 reporting and maintain vendor documentation.

Accounts Receivable (AR)

• • Generate and distribute customer invoices for products and services.
  • Post cash receipts and apply payments to customer accounts.
  • Monitor aging reports and follow up with customers on past-due balances.
  • Collaborate cross-functionally to ensure timely and accurate invoicing.
  • Support credit checks and assist with collections as needed.

Payroll

• • Process payroll, ensuring accuracy of hours, salaries, bonuses, and deductions.
  • Administer payroll taxes and employee benefit deductions in coordination with HR.
  • Process 401(k) contributions and ensure timely fundings.
  • Partner with the payroll provider to confirm all filings are accurate and up to date.
  • Maintain accurate employee records and assist with year-end W-2 reporting.

General Accounting

• • Prepare journal entries and perform account reconciliations.
  • Assist with month-end, quarter-end, and year-end close activities.
  • Support preparation of financial statements in accordance with GAAP.
  • Help maintain and improve internal controls, documentation, and accounting procedures.

• Bachelor’s degree in Accounting, Finance, or a related field.
• 1–3 years of accounting experience, including AP, AR, and payroll.
• Solid understanding of U.S. GAAP and the full accounting cycle.
• Proficiency with NetSuite, Bill.com, Expensify, and Microsoft Excel.
• Strong attention to detail, organizational skills, and ability to meet deadlines.
• Excellent communication and interpersonal skills; comfortable working cross-functionally.

What can Mission Bio offer you?

The base salary for this role is between $70,000 to $80,000 depending on experience.

Additional Benefits We Offer (US Only):

• Participation in the company’s long-term incentive programs, which ensure eligible employees participate in the company’s success
• Comprehensive benefits for U.S. employees, including medical, dental, and vision insurance, pre-tax commuter options, and a 401(k) plan
• Flexible working hours and an unlimited vacation policy to support personal well-being and productivity
• Training and professional development opportunities, including dedicated time with your manager to define growth goals and expand your expertise

Mission Bio is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. We welcome and encourage diversity in the workplace regardless of race, gender, sexual orientation, gender identity, disability or veteran status or any other characteristic protected by federal, state or local laws.

Agency Disclaimer:
Please note that Mission Bio is not accepting agency submissions for this role. Any resumes received from third-party recruiters or staffing agencies without a prior signed agreement will be considered unsolicited, and Mission Bio will not be obligated to pay any referral fees related to this position.