Senior Program Manager

Location: Hybrid/Onsite Presence Required, Boulder, CO

About the Company

Foresight Diagnostics is an early-stage, venture-backed molecular diagnostics company that is developing non-invasive cancer detection technologies to improve the lives of patients worldwide. Our portfolio of cell-free DNA based liquid biopsy tests are rooted in novel and proprietary methods developed at Stanford University. Our approach enables the earlier detection of smaller tumors, leading to more personalized and effective cancer treatment strategies for patients. We have deep expertise in molecular biology, bioinformatics, and Next Generation Sequencing (NGS), and maintain a dynamic, fast-paced work environment with significant opportunities for high-impact contribution and rapid professional growth. Foresight Diagnostics is headquartered in Boulder, Colorado.

About the Role

The Senior Program Manager will own, drive, communicate, and engage all project partners to enable accountability, problem solving, and on time delivery. To successfully execute at this level and with tight timelines, verbal communication and tool implementation, utilization, and management, paired with onsite presence (3 days a week) are critical to our shared success and our ability to deliver on Foresight’s mission. This is a full-time position working standard business hours, but may require the flexibility to work diverse schedules, including evenings, weekends, and holidays. The Program Manager role reports into the SVP, Business and Laboratory Strategy & Operations.

What You Will Do

Technical

• Lead end-to-end delivery of LIMS/LIS and lab informatics software work streams from initial scoping through validation, go-live, and post release support.

• Orchestrate SDLC and CSV in a regulated setting (IQ/OQ/PQ, Part 11, change control), with clear status/risk reporting to leadership.

• Support the integration of instruments, automation, and bioinformatics pipelines with LIMS via APIs/HL7/FHIR; manage migrations, UAT, training, and software release readiness.

• Lead project planning and execution, including scope, schedule, budget, and resource management and product design and development, ensuring processes are followed in accordance with regulations and general controls.

• Develop project strategy and plans achieving buy-in from leadership and stakeholders.

• Communicate project status, issues, and risks to senior leadership and stakeholders.

• Ensure stakeholders/team members understand and adhere to project scope, coordinate on process development, implementation, and improvement, efficiently and effectively assess and remediate technical issues, and manage changes through defined change control protocols.

• Extract and refine user needs and requirements from stakeholders.

• Guide teams to focus on the most valuable deliverables.

• Communicate product status and risks to cross functional teams.

• Support the technical teams with Agile implementation and ceremony execution.

• Facilitate and encourage collaboration across departments to ensure projects are completed successfully, within budget and on time.

• Develop project and program management tools and conduct opportunity and risk management activities including identification, mitigation and realization for assigned projects/programs.

• Coordinate with the SVP, Business and Laboratory Strategy & Operations and peers to develop and implement project management policies, procedures, and standards.

• Identify opportunities for improvement in portfolio level processes, inform senior leadership of proposed solutions, and collaborate on implementation.

What You Will Bring

• Proven track record shipping Lab Informatics software, LIMS features in CLIA/CAP settings, including validation deliverables and inspection preparation.

• Practical experience with LIMS platforms/programs and data exchange standards (e.g., LabWare/LabVantage; HL7/FHIR/REST) will be a plus.

• Strong Agile program skills (Jira/Confluence) with requirements-to-test traceability and vendor/SOW management.

Team

• Cultivate, build and maintain positive and collaborative relationships within teams and cross-functionally.

• Partner with Alliance Management Team to ensure successful internal and external partner engagement and execution to delivery timelines.

• Operate as a thought leader and hold cross-functional teams accountable to regulatory, quality, scientific and performance standards.

• Foster a culture of continuous improvement, identifying areas for process improvement and implementing changes as appropriate.

What You Will Bring

• 5+ years of experience in project/product management, with experience in biotechnology and clinical lab industries including direct experience delivering LDT and IVD products in FDA and CAP/CLIA regulated environments.

• Program and product management experience supporting diagnostics, MRD experience preferred.

• PMP or other project management certifications preferred.

• Proven track record of successfully managing complex projects from initiation to closure and have led projects bringing products to market in a biotechnology environment (diagnostics product experience preferred).

• Proficiency in project management tools and software.

• Ability to influence without power.

• Energy, motivation, and flexibility with excellent oral and written communication.

• Situational awareness, coupled with facilitation, problem solving, and conflict resolution skills to drive cross-functional decision-making.

• Familiarity with design control, translating user needs to product requirements, agile development, SWOT analysis, and product lifecycle management tools.

• Ability to manage multiple projects and tasks concurrently with strong attention to timeline and performance metrics.

• Demonstrated ability to work in a dynamic fast-paced environment, establish, and meet deadlines for product delivery.

• Experience developing complex diagnostics including assay and software components.

• Ability to think critically to overcome hurdles and devise solutions.

• This position may be required to work across time zones as needed to support project schedules.

Physical and Mental Requirements, Working Conditions

• Learn new tasks, remember processes, maintain focus, complete tasks independently, make timely decisions in the context of a workflow, ability to communicate with others, ability to complete tasks in situations that have a speed or productivity quota.

• Sedentary work. Exerting up to 10 pounds of force occasionally and/or negligible amount of force frequently or constantly to lift, carry, push, pull or otherwise move objects. This position requires close visual acuity to perform an activity such as: preparing and analyzing data and figures; transcribing; viewing a computer terminal; extensive reading.

• Work is performed in an office environment and requires the ability to operate standard office equipment and keyboards. Must have the ability to walk short distances, and/or drive a vehicle to deliver and pick up materials.

• This position requires the ability to identify and resolve quality issues.

• This position is full-time and requires an on onsite and in-person presence at least three (3) days per week in Boulder, CO.

Compensation and Benefits

This role is offering a salary between $145,000-185,000 and is bonus eligible. Foresight offers benefits including paid vacation, sick time, and parental leave (if applicable), alongside medical, dental, vision, life, disability coverage, flexible spending accounts, and a 401k with company match.

The application deadline for this job opening is December 15, 2025.

You will be working on interesting problems with extremely high impact. We promote the professional development of our employees and will encourage upward mobility within the company for high performing employees. Foresight Diagnostics is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.