Senior Manager, IT Business Partner – Commercial Systems

About CG Oncology, Inc.

Are you ready to make a difference in the world and become part of our patient-centered team that is focused on Attacking Bladder Cancer for a Better Tomorrow? At CG Oncology, we believe that by having exceptionally talented individuals on our team who share our passion and enjoy working together, we can truly achieve our Vision and Mission to benefit patients around the world.

Every day we are making significant advancements across our multiple pipelines and are growing rapidly to meet the needs of our patients who cannot afford to wait to benefit from our novel immunotherapies. Please review this job posting and our Values and if they resonate with you and are what you expect from your organization and team, then we would like to hear from you.

About the role

The Senior Manager, IT Business Partner – Commercial Systems is responsible for providing IT-owned support, administration, and business partnership for CG Oncology’s enterprise systems across the Commercial environment. This includes systems supporting Patient Access, Sales & Market Access, Communications & Patient Advocacy, Marketing, Business Analytics & Operations, Strategy & Business Operations and related Commercial business processes.

This role serves as the IT partner for assigned Commercial applications, with responsibility for system administration, access management, vendor coordination, issue resolution, release support, change control, system lifecycle documentation, and commercialization efforts. The position partners closely with commercial business system owners to ensure systems are identified, implemented, configured, maintained, secured, and supported in a compliant, scalable, and business-aligned manner.

This role operates under a clear separation of accountability between business and technology teams. Business Owners are responsible for defining requirements, aligning initiatives to business priorities, driving use‑case adoption, and partnering on end‑user enablement. Technology Owners (IT) are accountable for platform performance, user experience, security, architecture, integrations, onboarding, upgrades, and lifecycle management. This model ensures clarity of ownership, scalability, and effective partnership.

This role does not own front-end business process execution, operations, or functional data ownership. Those responsibilities remain with the applicable business system owners within each function. Reporting to the Senior Director, IT, this role supports a clear separation between functional business ownership and IT systems administration while helping CG Oncology build a scalable enterprise support model as the company advances toward commercialization.

Location: Remote

Essential Functions

• Enterprise Systems Support and Administration
• • Provide IT-owned support and administration for assigned Commercial enterprise systems across Patient Access, Market Access, Sales Operations, Sales, Communications & Patient Advocacy, Marketing, Business Analytics & Operations, Strategy & Business Operations and related Commercial business processes.
  • Provide sustainable operational support for Commercial systems such as CRM, data warehouse, EDI, Master Data Management, Alignment, Call Plans, IC, marketing technologies, …etc. Log, track, prioritize, and resolve system administration requests, incidents, and service tickets, ensuring timely resolution, appropriate escalation, adherence to defined SLAs, and ongoing ownership, maintenance, and operational excellence.
  • Act as a bridge across Commercial and enterprise data domains, partnering with Finance, Compliance, HR, and other functions to reinforce a single, governed, and scalable enterprise data foundation.
  • Leverage the existing data warehouse as a system of record, improve connectivity and data flow across platforms, and prevent the creation of parallel or fragmented data environments through standardization and integration discipline.
  • Manage back-end system administration activities, including user access, role assignments, permissions, workflows, configuration updates, support tickets, and system maintenance.
  • Serve as an IT point of contact for assigned Commercial applications, ensuring systems are supported in a compliant, secure, scalable, and business-aligned manner.
  • Support system availability, issue triage, troubleshooting, escalation, and resolution in partnership with vendors, IT, and functional business owners.
  • Accountable for overall health, compliance posture, and performance of assigned Commercial systems throughout their lifecycle.
  • Accountable for system architecture across the commercial landscape and integrations between systems, including data flows and integrations between Commercial, Finance, Compliance, HR, and enterprise platforms
  • Guide the RFP process and align internal stakeholders to requirements to assess viable solutions that best fit the needs
• IT Business Partnership and Functional Alignment
• • Compile and synthesize Commercial business needs across Patient Access, Sales & Market Access, Channel Strategy, Pricing, Omnichannel, Communications & Patient Advocacy, Marketing, and related Commercial functions.
  • Facilitate formal governance forums to review, align, and prioritize system‑related requests. Drive documented decision‑making and obtain formal sign‑off through a core Commercial business committee, operating under defined rules of engagement and escalation.
  • Partner with business system owners and functional stakeholders to understand system needs, document requirements, seek solutions, support gaps, and improvement opportunities.
  • Lead the development, maintenance, and execution of business system roadmaps (internal and product driven), ensuring alignment with business priorities, regulatory requirements, and IT strategy.
  • Collaborate with business and Finance stakeholders to identify, estimate, and plan budget requirements for IT initiatives and system components defined in the systems roadmap, supporting annual and long‑range planning.
  • Ensure enterprise alignment and scalability. Lead the selection and implementation of technology solutions that align with enterprise architecture standards, integrate with existing systems, support cross‑functional needs, and scale with business growth.
  • Drive operational rigor in regulated environments. Apply structured governance, best practices, and lifecycle discipline to technology initiatives, including the implementation and expansion of Commercial systems to meet evolving regulatory and business requirements.
  • Translate business needs into IT support requirements, system enhancements, configuration requests, vendor tickets, and implementation plans.
  • Maintain clear separation between functional business process ownership and IT systems administration responsibilities.
  • Provide cross-functional coordination across IT, Patient Access, Sales & Market Access, Communications & Patient Advocacy, Marketing, Business Analytics & Operations, Strategy & Business Operations, and external vendors.
  • Balance regulatory, operational, and business priorities across multiple systems and stakeholder groups.
  • Help partner with the business systems owners to build, maintain and secure data assets that align with IT policies •
  • Stay up to date with the ever-changing landscape and technology trends that support commercial operations and IT
• Compliance, and Audit Readiness
• • Support Commercial system lifecycle and releases (internal and product). Coordinate system changes, enhancements, and releases through defined processes, including impact assessments, testing coordination, documentation updates, and ongoing system lifecycle supports.
  • Ensure compliant Commercial system support. Align assigned system support activities with applicable Commercial regulatory and compliance requirements, including data privacy laws (e.g., GDPR, CCPA), Sunshine Act / Open Payments reporting, SOX‑relevant controls, internal SOPs, data integrity standards, and company policies.
  • Maintain audit-ready documentation for system administration, access control, configuration, change management, and vendor support activities.
• Vendor, Release, and Change Management
• • Coordinate with technology vendors on system releases, upgrades, support tickets, enhancement requests, defects, and issue resolution.
  • Assess the impact of vendor updates and system changes, including required testing, documentation, training, and stakeholder communication.
  • Track and communicate system issues, risks, dependencies, and upcoming changes to appropriate stakeholders.
  • Support vendor performance monitoring and escalation for assigned Commercial systems.
• Process Improvement and System Lifecycle Management
• • Identify opportunities to improve system usability, compliance, scalability, efficiency, and cross functional support.
  • Lead the development and maintenance of system roadmaps, architecture, support models, SOPs, work instructions, and governance practices for assigned Commercial systems.
  • Drive remediation of incomplete or sub‑optimal integrations (e.g., collaboration platforms), rationalize the technology stack, improve interoperability, and ensure systems are fully connected and delivering measurable business value.
  • Partner with IT leadership and business owners prioritize enhancements, resolve gaps, and mature enterprise systems support as CG Oncology scales.
  • Partner with business system owners to prioritize adoption initiatives, standardize usage patterns, and drive measurable outcomes from existing technology investments.
• User Enablement and Documentation
• • Support user enablement, system training coordination, communication of system changes, and adoption of standardized processes.
  • Maintain system support documentation, user guides, access records, configuration records, artifacts, and related IT/Commercial documentation.
  • Provide guidance to users on system support pathways, issue escalation, and appropriate use of assigned applications.
  • Build and maintain knowledge base for commercial technologies

Qualifications

• Bachelor’s degree in information technology, computer science, business systems, life sciences, engineering, or a related field.
• Seven years of progressive experience supporting enterprise systems, business applications, IT systems, or regulated technology platforms in biotech, pharmaceutical, life sciences, or another regulated environment.
• Experience supporting Commercial systems across one or more functional areas, such as Patient Access, Sales & Market Access, Communications & Patient Advocacy, Marketing, Business Analytics & Operations, Strategy & Business Operations, data warehouse, master data management, CRM, marketing technologies or related business functions.
• Working knowledge of Commercial requirements, system development life cycle, change control, access management, data integrity, compliance readiness, and system lifecycle support.
• Experience with enterprise application administration, including user access, role permissions, workflows, configuration support, issue triage, release support, and vendor coordination.
• Demonstrated ability to partner with business system owners, IT, vendors, and cross-functional stakeholders to support regulated applications.
• Ability to translate business needs into IT support requirements, system enhancements, implementation plans. configuration requests, and
• Strong communication, documentation, problem-solving, and stakeholder management skills.
• Available for limited domestic travel as business needs require.

Please note that CG Oncology does not accept unsolicited information and/or resumes from search firms or agencies for our job postings. Any resumes or client information submitted to our careers page or any employee of CG Oncology by any search firm or agency without an applicable contract in place will become the property of CG Oncology and no fee(s) will be paid.

Total Rewards

CG Oncology offers very competitive and comprehensive Total Rewards, helping to support and reward our global team of high-performing employees focused on developing bladder-saving therapeutics for patients afflicted with bladder cancer.

• HIGHLY COMPETITIVE SALARIES   
• ANNUAL PERFORMANCE/MERIT REVIEWS
• ANNUAL PERFORMANCE BONUSES
• EQUITY
• SPECIAL RECOGNITION

Well-Being Benefits

In addition to our Total Rewards, CG Oncology offers a variety of Well-Being Benefits to meet the majority of the needs of our unique and growing workforce.  These benefits are designed to support our team to achieve a healthy balance between work and their personal lives to remain refreshed, engaged, and creating an environment where each person can find a deeper meaning and purpose in their work.

Well-Being Benefits eligibility begins the 1st of the month after hire.  While a majority of these benefits are for our US-based workforce, we continue to assess comparable levels of benefits for our international team members that are aligned with country-specific regulations and their national programs offered.

• FULLY REMOTE WORK ENVIRONMENT
• REST AND RECHARGE BENEFITS - Unlimited Flexible Time Off
• HOLIDAYS –In 2026 we will observe 14 holidays
• RETIREMENT – 401K with 100% company Safe Harbor match up to 4% of base salary
• HEALTH (MEDICAL, DENTAL, VISION) – PPO & HDHP – Cigna/Principal
• HEALTH SPENDING ACCOUNTS - HSA (with Annual Company Contribution), FSA, FSA-DC
• ILLNESS & DISABILITY PROTECTION – Company Paid LTD Coverage + Voluntary Plans
• LIFE INSURANCE – Company Paid 1 x base salary + Voluntary Plans
• ADDITIONAL EXCLUSIVE BENEFITS – Voluntary Legal, Pet, Plus More

CG Oncology is an Equal Opportunity Employer:

All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.  At CG Oncology, we are building a community of intelligent and passionate team members that share our Vision, Mission and Values, and while the biotechnology space can feel limited in BIPOC, non-binary and even female representation, we endeavor to make hiring decisions that will continue to grow and support our team in the direction of maintaining cultural diversity and sustainability.