Senior Director, Strategic Portfolio Management Team Lead

Role Summary:
Are you energized by the chance to bring clarity and simplicity to complex challenges? As Senior Director, Strategic Portfolio Team Lead, you'll transform Pfizer's digital portfolio management from a patchwork of processes into a unified, streamlined engine for innovation. You'll architect the standards, tools, and practices that empower portfolio leaders across every Center of Excellence and Creation Center to deliver on our boldest ambitions.
You will serve as the enterprise architect and challenger for Pfizer's digital investment agenda - ensuring every initiative is rigorously aligned to our digital strategy and future vision. You will partner with the Portfolio Leads to proactively inspect, challenge, and recommend bold moves to optimize resource allocation, accelerate value creation, and drive operational discipline. You will influence and enable the Digital & Technology Leadership Team to act with discipline and foresight-making recommendations that help fund the few, finish the vital, and re-balance as priorities shift.
Role Responsibilities:

• Enterprise Portfolio Strategy & Governance
  • Set and govern the standards, methodologies, and tools for portfolio management across the enterprise, ensuring consistency, transparency, and strategic alignment.
  • Lead cross-functional prioritization and value realization efforts, partnering with Digital & Technology LT and portfolio leads to optimize resource allocation and maximize business impact.
  • Continuously assess the portfolio through rigorous reviews, surfacing start/stop/scale recommendations that keep investments aligned to Pfizer's digital strategy.
• Innovation & Continuous Improvement
  • Champion the integration of AI, advanced analytics, and best-in-class practices to modernize portfolio management and accelerate decision-making.
  • Act as a change agent, driving continuous improvement and fostering a culture of innovation and accountability.
  • Identify low-value work, bottlenecks, and duplication across portfolio processes; recommend simplification, standardization, and automation in partnership with Digital Process Reinvention Lead.
• Strategic Collaboration & Influence
  • Collaborate with the Portfolio Value Storyteller and Reinvention team to ensure a unified, compelling narrative for digital investments and to reimagine portfolio processes.
  • Influence senior management decisions, providing strategic recommendations that shape the direction of Pfizer's digital transformation.
  • Make actionable recommendations to Digital & Technology leaders on portfolio optimization.
• Center of Excellence Leadership
  • Operate as the strategic leader of a Center of Excellence for portfolio management, ensuring that standards, insights, and innovations are shared and adopted across all business units.
• Leadership & Enablement
  • Build, mentor, and empower a high-performing team (2-4 direct reports), cultivating a culture of innovation, accountability, and continuous learning.
  • Mobilize matrixed resources and partnerships to deliver breakthrough results.
  • Provide transparent insights, dashboards, and decision intelligence that enable senior leaders to act proactively and decisively.

BASIC QUALIFICATIONS

• A bachelor's degree (digital technology preferred)
• 12+ years in portfolio management, strategy, or program leadership roles.
• Proven experience developing and implementing enterprise-wide standards or tools.
• Demonstrated ability to lead cross-functional teams and influence at the executive level.
• Experience with digital transformation and AI-enabled portfolio practices.
• Recognized thought leader in digital transformation and portfolio management.
• Experience leading in large, matrixed organizations.
• Strong analytical skills and proficiency with portfolio management tools.
• Exceptional communication and stakeholder engagement capabilities.

PREFERRED QUALIFICATIONS

• MBA or relevant advanced degree

Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

• Our business is a 7x24x365 endeavor. This role may on occasion require physical or virtual participation on a weekend, holiday, or after normal business hours.

Work Location Assignment: Hybrid
Last Date to Apply for Job: 1/6/2026
The annual base salary for this position ranges from $204,700.00 to $341,100.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 22.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
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