Lead Program Manager (SAP)

McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve – we care.

What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow’s health today, we want to hear from you.

McKesson is in the business of better health, and we touch the lives of patients in virtually every aspect of healthcare. We partner with payors, hospitals, physician offices, pharmacies, pharmaceutical companies, and others across the spectrum of care to build healthier organizations that deliver better care to patients in every setting. We believe in the importance of strong, vital organizations because we know that patients can only be healthy when our system is healthy.  

Every single McKesson employee contributes to our mission—by joining McKesson you act as a catalyst in a chain of events that helps millions of people all over the globe. Talented, compassionate people are the future of our company—and of healthcare. At McKesson, you’ll collaborate on the products and solutions that help us carry out our mission to improve lives and advance healthcare. Working here is your opportunity to shape an industry that’s vital to us all. 

Position Description

As a Lead Program Manager, you will be responsible for delivering large-scale, enterprise-wide modernization and transformation initiatives that align with McKesson’s strategic goals and Enterprise Architecture (EA) standards. This role requires strong leadership, the ability to drive execution across complex technological ecosystems, and experience working with enterprise platforms such as SAP, Oracle, and major integration technologies. The Lead Program Manager will serve as the connection point between business strategy and technical execution, ensuring programs deliver value, compliance, and scalability.

The Lead Program Manager will provide senior-level leadership for enterprise technology programs, ensuring strategic alignment, execution excellence, and adherence to Enterprise Architecture standards.

This role will:

• Drive end-to-end delivery of SAP, Oracle, and integration modernization programs.

• Act as a bridge between business leadership, Enterprise Architecture, and IT delivery teams.

• Oversee program budgets, risk management, and compliance adherence.

• Ensure platform implementations are secure, scalable, interoperable, and cost-efficient.

• Lead change management to maximize adoption and business value realization.

The successful incumbent will perform the following duties:

• Enterprise Architecture Alignment: Ensure program designs comply with EA frameworks, long-term roadmaps, and architectural standards.

• Program Management: Track record managing large-scale, multi-platform initiatives involving SAP, Oracle, and cross-system integrations.

• Vendor & Partner Management: Oversee large vendor ecosystems to deliver ERP and integration programs.

• Leadership & Collaboration: Influence across business, IT, and EA to align delivery with enterprise strategies.

• Governance & Compliance: Experience with SOX, HIPAA, GDPR, and data security frameworks.

• Financial Acumen: Manage budgets and cost optimization for enterprise programs.

• Adaptability: Ability to manage change in complex, dynamic environments.

Key Responsibilities

Program Leadership

• Lead end-to-end delivery of enterprise technology programs, ensuring compliance with Enterprise Architecture frameworks, standards, and governance.

• Manage program charter, roadmaps, budgets, risks, and cross-functional execution across multiple business units.

• Partner with Enterprise Architects to validate solutions, ensuring alignment with the target architecture and long-term technology strategy.

• Act as liaison between business stakeholders, IT teams, integration architects, and third-party vendors to ensure cohesive delivery.

• Collaborate with IT, operations, finance, legal, security, and customer-facing teams to deliver measurable business outcomes.

Strategic Alignment

• Translate enterprise objectives into actionable initiatives that leverage platforms such as SAP (ERP, supply chain, finance), Oracle (databases, applications), and integration technologies (APIs, middleware, cloud iPaaS).

• Identify architecture gaps and drive modernization programs to simplify legacy landscapes and enable interoperability across platforms.

• Drive continuous improvement of program management processes and ensure integration of new technologies supports EA standards.

Stakeholder Collaboration

• Drive collaboration with enterprise architecture, business leaders, and technical teams to ensure alignment with long-term roadmaps.

• Lead change management and adoption efforts to integrate new SAP, Oracle, or integration solutions into business operations.

• Provide executive-level communications on program progress, risks, and outcomes.

Program Delivery

• Oversee implementation and modernization of enterprise platforms (SAP S/4HANA, Oracle Cloud, middleware/integration services, and analytics platforms).

• Ensure programs deliver secure, scalable, and compliant solutions that integrate effectively with McKesson’s technology ecosystem.

• Support integration initiatives to connect SAP, Oracle, SaaS platforms, and cloud-native services using APIs, middleware, and ETL tools.

Governance, Risk & Compliance

• Ensure programs adhere to EA governance, data privacy, and compliance frameworks (HIPAA, GDPR, SOX).

• Conduct architecture reviews and risk assessments to minimize technical debt and ensure platform integrity.

Performance Metrics & Continuous Improvement

• Define and track KPIs measuring adoption, performance, and business impact of SAP, Oracle, and integration solutions.

• Identify opportunities to streamline processes, enhance interoperability, and reduce cost through continuous improvement.

Minimum Requirements:

Typically requires 10+ years of relevant experience

Critical Skills:

• 10+ years of professional experience with 8+ years leading enterprise-scale technology programs.

• Proven experience managing large transformation programs involving SAP, Oracle, integration middleware, and enterprise applications.

• Strong understanding of Enterprise Architecture principles, technology roadmaps, and governance frameworks.

• Enterprise Platforms: Hands-on experience with SAP (ERP, supply chain, finance), Oracle applications/databases, and integration technologies (APIs, middleware, iPaaS).

• Experience driving digital transformation, cloud adoption, and enterprise integration at scale.

• Vendor management experience, including contract negotiation and performance oversight.

• PMP, SAFe, TOGAF, or equivalent certification preferred.

• Strong analytical, problem-solving, and financial management skills.

Additional Knowledge/Skills

• Excellent stakeholder management, communication, and leadership skills.

• PMP, SAFe, TOGAF, or equivalent certification preferred.

• Strong analytical, problem-solving, and financial management skills.

Education

• Bachelors degree or equivalent experience

We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. The pay range shown below is aligned with McKesson's pay philosophy, and pay will always be compliant with any applicable regulations. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered. For more information regarding benefits at McKesson, please click here.

Our Base Pay Range for this position

McKesson is an Equal Opportunity Employer

McKesson provides equal employment opportunities to applicants and employees and is committed to a diverse and inclusive environment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, age or genetic information. For additional information on McKesson’s full Equal Employment Opportunity policies, visit our Equal Employment Opportunity page.

Join us at McKesson!