Lead Program Manager, Enterprise M&A and Business Transformation

McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve – we care.

What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow’s health today, we want to hear from you.

Job Title: Lead Program Manager, Enterprise M&A and Business Transformation

Current Need:

Mckesson's Lead Program Manager will participate in leading the planning, execution, and governance of complex IT separation and Transition Service Agreement (TSA) initiatives in support of a major corporate transaction. This role spans the full transaction lifecycle, managing pre–Day 1 readiness, TSA definition and enablement and post–Day 1 operational stabilization, including licensing continuity, cost optimization and rapid TSA exit planning. The Program Manager will coordinate cross-functional teams to ensure services across applications are identified, bundled, costed, enabled, and successfully transitioned to future-state operations.

Key Responsibilities:

• Program Leadership & Governance – 40% - Lead in the end-to-end delivery of TSA scope definition, schedule build, enablement workstreams, and post–Day 1 stabilization, ensuring alignment with transaction timelines and strategic objectives. Establish governance cadence, manage project schedules and dependencies and participate in building M&A playbook as required. Provide consistent status reporting as well as develop other artifacts needed for Steering Committee meetings and other ELT reviews. Assist in managing associated vendors in support of various workstreams and deliverables.

• IT Separation Readiness & Execution – 25% - Participate in planning and execution of IT separation activities, including application disposition, rationalization, disentanglement, data separation, network engineering, and sourcing/commercial deliverables. Monitor service delivery, resolve operational issues, ensuring service continuity during the TSA period. Support TSA exit plans, including transition timelines, cutover sequencing, licensing agreement optimization, knowledge transfer, and readiness testing for new service providers or internal ownership.

• Cross-Functional Stakeholder Engagement – 15% - Facilitate collaboration at the working level between IT, business units, legal, finance, sourcing, and external partners to ensure pre- and post- Day 1 deliverables are accurate, feasible, and mutually agreed. Resolve conflicts and maintain alignment across workstreams.

• Risk & Issue Management – 10% - Proactively identify and communicate risks related to TSA delivery, IT separation, and transaction interdependencies. Escalate critical blockers with recommended solutions.

• Change Management & Communication – 10% - Lead structured change management for separation initiatives, ensuring impacted stakeholders are informed, trained, and prepared for operational transition.

Critical Business Experience:

• 10+ years of program management experience in large-scale IT or M&A separation programs.
• Experience managing multi-million-dollar budgets and complex interdependent schedules.
• Strong background in IT infrastructure, applications, portfolio management, and cross-functional business engagement.

Specialized Knowledge/Skills:

• Understanding of Transition Service Agreements (scope, costing, bundling, run/enablement costs).
• Strong governance, risk management, and vendor management capabilities.
• Excellent facilitation, communication, and executive stakeholder management skills.
• Ability to operate effectively in a fast-paced, high-stakes transaction environment.

Minimum Qualifications:

• Education: Bachelor’s in Business, IT, or related field; PMP preferred; Agile SAFe a plus.
• Experience: Typically requires 13+yrs of experience with over 10+ years in program management, especially in IT/M&A separation; budget and schedule management.
• Skills: TSA knowledge, governance, vendor management, stakeholder communication, and ability to thrive in high-stakes environments.

Working Conditions: Environment (Office, warehouse, etc.) – Traditional office or remote work environment with periodic travel for key program milestones and stakeholder meetings.

Travel requirement: 10%

Relocation is not budgeted for this role

Candidate must be authorized to work in the U.S, now or in the future, without the support from McKesson.

We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. The pay range shown below is aligned with McKesson's pay philosophy, and pay will always be compliant with any applicable regulations. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered. For more information regarding benefits at McKesson, please click here.

Our Base Pay Range for this position

McKesson is an Equal Opportunity Employer

McKesson provides equal employment opportunities to applicants and employees and is committed to a diverse and inclusive environment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, age or genetic information. For additional information on McKesson’s full Equal Employment Opportunity policies, visit our Equal Employment Opportunity page.

Join us at McKesson!