Natera is at the forefront of personalized genetic testing, transforming the management of disease worldwide. We are seeking a seasoned and visionary Director of Product Management to lead the software product strategy and development for our Comprehensive Genomic Profiling (CGP) portfolio.
This is a critical leadership role where you will act as the "Orchestrator" and executive sponsor for the end-to-end CGP software ecosystem. You will own the full product lifecycle—from sample order to report delivery—acting as the bridge between cutting-edge R&D, clinical operations, and engineering. You will lead the transition of our Altera product from a send-out model to a fully in-house, leveraging our new high-throughput sequencing architecture.
This role requires a leader who thrives in a complex, regulated environment, possessing the strategic vision of a product leader combined with the execution rigor of a seasoned operator. You will live the ethos of agile, user-centered development with high agency and urgency, driving the team to navigate ambiguity and deliver critical milestones.
Key ResponsibilitiesStrategic Leadership & Vision- Define the CGP Software Vision: Develop and execute the multi-year software product roadmap for the CGP portfolio, balancing the need for rapid feature development with long-term commercial stability and regulatory compliance.
- The "L2" Architect: Translate high-level business goals (L1) into detailed functional workflows (L2 requirements) that component Product Owners consume to create their specific user stories. You are accountable for the cohesion of the final solution.
- End-to-End "Sample-to-Report" Ownership: Ensure that the sample journey remains unbroken across system boundaries (Portal -> LIMS -> Bioinformatics -> Report).
- Founder’s Mindset: Champion a culture of "high agency" and urgency, driving the team to make quick, data-driven decisions in ambiguous situations and deliver critical milestones in a fast-paced environment
- Focused Development: Lead the software strategy for bringing our tumor an liquid CGP products in house, moving from external partner integrations to a native Natera software stack.
- Operational Immersion: Passionately advocate for the needs of internal users (lab scientists, accessioning teams) by regularly shadowing operations to ensure software solves real physical problems in the lab
- Cross-Functional Orchestration: collaborate closely with Computational Biology, Bioinformatics, and Engineering teams to productionize complex algorithms into scalable clinical workflows. You will bridge the gap between scientific intent and software reality.
- Communication: Exceptional written and verbal communication skills, with the ability to simplify complex ideas for diverse audiences and influence stakeholders at all levels
- Systems Thinking: Ability to see the "big picture" and understand how software systems interact across the entire sample lifecycle
- Project Delivery: Drive project execution with the rigor of a seasoned project manager, ensuring cross-functional teams (Engineering, R&D, Lab Ops, Quality, Regulatory) stay on track to meet critical deadlines
- Agile Mastery: Expert in Agile methodologies and software development lifecycles
- Culture Building: Foster a product culture of accountability, user experience rigor, and cross-functional collaboration within the Oncology software unit.
- Mentorship: Mentor and guide Senior Product Managers and cross-functional team members, instilling best practices in product management and agile development.
- Experience: 10+ years of product management experience in healthcare IT, biotech, or software, with at least 5 years in a leadership role.
- Domain Knowledge: Deep familiarity with Oncology, Comprehensive Genomic Profiling (CGP), and Next-Generation Sequencing (NGS) workflows is required.
- Zero-to-One Track Record: Proven experience building and launching "Zero-to-One" software products.
- Regulated Industry Expertise: Deep experience in a highly regulated environment, with
- Technical Aptitude: Strong ability to understand technical complexities (APIs, LIMS architecture, Bioinformatics pipelines) and communicate effectively with engineering and scientific teams
- Education: BS/MS in a relevant technical, scientific, or quantitative discipline (MBA or PhD is a plus)
Compensation & Total Rewards
This range reflects a good-faith estimate of the base pay we reasonably expect to offer at the time of hire. Final compensation will vary based on experience, qualifications, and internal equity considerations.
This position is also eligible for additional compensation and benefits through Natera’s robust Total Rewards program, including:
Annual performance incentive bonus
Long-term equity awards
Comprehensive health benefits (medical, dental, vision)
401(k) with company match
Generous paid time off and company holidays
Additional wellness and work-life benefits
OUR OPPORTUNITY
Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.
The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.
WHAT WE OFFER
Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!
For more information, visit www.natera.com.
Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.
All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.
If you are based in California, we encourage you to read this important information for California residents.
Link: https://www.natera.com/notice-of-data-collection-california-residents/
Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.
For more information:
- BBB announcement on job scams
- FBI Cyber Crime resource page
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