Jobs at Natera

On-site senior IT resource for a 25–75 person site who owns Level 2–3 escalations, end-user support, endpoint provisioning/imaging, and site networking. Partners with central IT on standards, security, and projects while managing vendors, inventory, access, and local compliance; documents runbooks and provides escalation/backstop support.

Lead a team of Laboratory Systems Scientists to implement, optimize, and scale laboratory systems and processes. Drive continuous improvement, technology transfer, asset management, and cross-functional operationalization to support high-throughput, regulated molecular testing. Partner with R&D, Bioinformatics, Software, Automation, Quality, Regulatory, and Product to align lab workflows with business objectives.

Design, develop, and execute manual and automated test cases for laboratory software in a CLIA-regulated environment. Validate functionality, data integrity, and workflows (including NGS-related processes), track defects, support verification/validation activities, maintain traceability and documentation, participate in risk assessments, and collaborate with lab operations, engineering, and quality teams to ensure compliant, reliable patient testing systems.

Lead evolution and governance of corporate and product brands, build scalable brand systems and creative operations, direct creative strategy and execution across channels, manage internal teams and external agencies, and partner cross-functionally to ensure consistent, high-quality brand experiences supporting rapid global growth.

Lead test architect for end-to-end integration testing of a complex genomics product portfolio. Design contract-first validations (OpenAPI/Avro), build resilient API and event-driven test frameworks, embed LLM-driven test generation and log analysis into CI/CD, mentor SQEs, enforce staging guardrails, and run chaos/resiliency experiments across distributed microservices.

The Principal, Pharmacovigilance / Device Vigilance oversees safety surveillance, adverse event management, and regulatory compliance for medical devices and diagnostics, ensuring patient safety throughout product lifecycle.

Lead technical architecture and delivery for Oracle Fusion and enterprise integrations. Own Fusion integration patterns, extension design, upgrade governance, data and reporting enablement, and platform health. Manage integration and platform engineers, enforce code/config governance, drive predictable delivery, and enable intelligent automation and AI governance across ERP and enterprise tools.

The role involves supporting strategy and operations across R&D, product, and commercial domains, focusing on alignment, execution, and visibility for diverse initiatives in precision medicine.

Lead multiple concurrent IVD development programs from initiation through commercialization, owning integrated schedules, risk registers, change control, and PMA submission readiness. Serve as primary PMO liaison to pharma/biotech partners, drive cross-functional alignment and governance, standardize PMO frameworks to meet 21 CFR Part 820/ISO 13485, mentor junior PMs, and partner with Finance on budgets and resource planning.

Lead and expand biopharma partnerships in Organ Health by sourcing, negotiating, and executing complex deals. Guide cross-functional deal teams, assess market opportunities, provide strategic insights to leadership, and represent the company at industry events to drive partnership growth.

The Senior Generative AI Engineer will design and deploy AI/ML solutions, focusing on Generative AI systems and their operational excellence across various sectors like R&D and Clinical Trials.

Lead national account strategy for women's health accounts, build relationships with KOLs and large-group/PE organizations, drive adoption of Natera tests, coordinate with regional and field teams, develop strategic account plans, pursue RFPs/GPOs and contracting opportunities, attend trade events, and travel ~40-50% to grow volume and partnerships.

Lead verification and validation for clinical bioinformatics and device software. Design and execute V&V tests for NGS pipelines, lab automation, LIMS/LIS integrations, and reagents. Ensure IEC 62304 and ISO 13485 compliance, maintain traceability matrices, approve test reports, and coordinate cross-functional testing cadence. Support documentation for regulatory submissions and perform regular in-person testing and lab integration in Boulder.

Lead design and standardization of R&D portfolio management processes, governance, and integrated planning. Own portfolio data infrastructure, KPIs, and automated reporting. Provide financial modeling, budget governance, and investment performance tracking. Partner with R&D, Finance, and PMO to enable decision-ready insights and improve predictability, resource allocation, and portfolio transparency.

Manage assigned client billing accounts, resolve invoice disputes, negotiate payments, collaborate with Sales/Finance/internal teams, analyze billing trends, produce reports, drive revenue cycle improvements, and ensure HIPAA compliance when handling PHI.

Embed with a business domain to map workflows, design agent-enabled future-state processes, build and connect production automation (LLMs, agents, RAG), run and monitor agents with observability and evals, and partner with domain leaders to deliver measurable KPI improvements.

Lead product strategy and roadmap for core software supporting lab, R&D, clinical, and commercial workflows. Translate business, clinical, and user needs into detailed product requirements, prioritize feature backlogs, and drive cross-functional delivery with engineering, design, QA, and stakeholders. Define success metrics, produce diagrams/prototypes, solicit user feedback, and continuously improve product quality and operational efficiency.

The Software Engineer III - Voice AI develops and maintains the Voice AI platform for patient calls, optimizing real-time conversational AI features and mentoring team members.

Design and manage the voice AI architecture, developing multi-agent systems and real-time audio pipelines to enhance patient interactions and outcomes in healthcare.

Lead and scale a ~25-person EHR implementation and client services organization, owning end-to-end EHR integrations (Epic, Cerner, Meditech), operating model, processes, governance, and executive client engagement to ensure successful order/result workflows, interoperability, and post-launch support.