Jobs at ICON plc

Lead and perform clinical trial monitoring for Phase I oncology studies, ensure GCP and protocol compliance, conduct site visits, resolve issues, support data integrity, train site staff and junior CRAs, collaborate cross-functionally, and manage multiple sites with ~60% travel.

Conduct clinical trial site qualification, initiation, monitoring, and close-out visits for HemOnc studies. Ensure protocol compliance, data integrity, and patient safety; collaborate with investigators and site staff; review data and resolve queries; and support study documentation, protocols, and clinical study reports. Requires oncology monitoring experience, strong clinical trial knowledge, and willingness to travel 60–75% regionally.

Conduct clinical trial site qualification, initiation, monitoring, and close-out visits for oncology studies. Ensure protocol compliance, data integrity, and patient safety; collaborate with investigators and site staff; resolve data queries; and support preparation and review of study documentation. Requires at least two years of Clinical Research Associate experience, oncology monitoring experience, scientific or healthcare education, ICH-GCP knowledge, and willingness to travel 60–75% within the region.

Conduct site selection, initiation, monitoring, and close-out visits for clinical research studies. Serve as the sponsor-site contact, ensure ICH-GCP and regulatory compliance, maintain CTMS and eTMF documentation, monitor patient safety and drug accountability, support recruitment and retention, resolve data queries, track site progress and payments, and escalate risks while collaborating with clinical trial partners.

Conduct clinical trial monitoring for early-stage oncology studies, including site qualification, initiation, monitoring, and close-out visits. Ensure protocol compliance, data integrity, and patient safety; collaborate with investigators and site staff; resolve data queries; and support clinical study documentation. Requires at least two years of Clinical Research Associate experience, oncology monitoring expertise, a scientific or healthcare degree, and willingness to travel up to 50% within the assigned region.

Monitors oncology clinical trial sites for protocol, regulatory, and GCP compliance; conducts site visits, resolves issues, supports trial execution, and ensures data integrity. Collaborates with cross-functional teams, trains site staff and CRAs, manages multiple sites and projects, and maintains stakeholder relationships. Requires Colorado residence, oncology monitoring experience, at least 60% domestic and international travel, and a valid driver's license.

Conduct and oversee clinical study site activities for Phase II–IV dermatology and rare disease trials. Responsibilities include site identification, initiation, monitoring, close-out, regulatory and ethics submissions, documentation, query management, feasibility assessments, cost efficiency, and potential CRA mentoring. Requires strong knowledge of ICH-GCP, medical data review, bilingual German and English communication, and willingness to travel internationally and domestically at least 60% of the time.

Lead clinical trial monitoring activities to ensure protocol and regulatory compliance, conduct site visits, resolve issues, support data integrity, train site staff and CRAs, collaborate cross-functionally, and maintain strong site relationships to drive successful trial execution.

Oversee cardiovascular clinical trials, ensuring compliance with regulations while managing site relationships and communication. Requires 3 years of monitoring experience and strong problem-solving skills.

The Senior Clinical Research Associate manages monitoring for cardiovascular clinical trials, ensuring compliance with FDA regulations and guiding teams to resolve site issues effectively.

Lead site management and monitoring for Oncology clinical trials (Phase I/early development), ensuring data integrity, subject safety, inspection readiness, TMF reconciliation, KRI monitoring, CAPA implementation, site activation and training, and oversight/mentoring of CRAs while supporting regulatory inspections and fostering key site relationships.

Serve as primary contact between sites and sponsor for oncology (myelofibrosis) trials. Perform site selection, initiation, routine monitoring, and close-out visits; ensure ICH-GCP and regulatory compliance; maintain CTMS/eTMF documentation; monitor safety reporting (AE/SAE); support recruitment, drug accountability, data query resolution, and cross-functional escalation.

Lead on-site clinical monitoring for oncology/hematology trials: conduct site selection, initiation, routine and close-out visits; ensure ICH-GCP and regulatory compliance; maintain CTMS/eTMF documentation; monitor patient safety and AE/SAE reporting; oversee drug accountability, support recruitment and retention, resolve data queries, track site budgets, and escalate risks to clinical teams while collaborating cross-functionally.

Serve as primary contact between investigational sites and sponsor to conduct site selection, initiation, routine monitoring, and close-out. Ensure ICH-GCP and regulatory compliance, maintain CTMS/eTMF documentation, monitor patient safety (AE/SAE/PQC), support recruitment and drug accountability, resolve data queries, track site training and budgets, escalate risks, and collaborate with cross-functional clinical teams.

Leads clinical trial study start-up activities, including preparing and submitting regulatory and ethics documents, coordinating approvals, maintaining submission records, and advising study teams on regulatory requirements. The role supports process improvements and ensures compliance with ICON procedures, sponsor requirements, local regulations, and ICH-GCP. Candidates need at least one year of clinical research, regulatory affairs, or study start-up experience, strong organizational and communication skills, and a relevant bachelor’s degree.

Manages multiple healthcare improvement initiatives across timelines, budgets, workstreams, risks, deliverables, and stakeholder relationships. Coordinates Medical Affairs, Legal, compliance, health systems, professional societies, research institutes, and other partners. Tracks spending and milestones, supports governance meetings, synthesizes performance data, maintains project dashboards and collaboration tools, conducts landscape analyses, and identifies process improvements. Requires healthcare systems knowledge, quality improvement exposure, and CRO or pharma project management experience.

Leads clinical outcome assessment (COA) research programs, including PRO, ClinRO, PerfO, and ObsRO development and validation. Designs qualitative and psychometric research, supports clinical trial protocols and statistical plans, prepares regulatory documents, develops COA strategies, and publishes findings. Requires collaboration with cross-functional teams, regulators, patients, caregivers, payers, and external partners across multiple therapeutic areas.

Manage and monitor clinical trial sites including qualification, initiation, monitoring, and close-out visits. Ensure protocol compliance, data integrity, patient safety, query resolution, and contribute to study documentation and reports.

Leads clinical data science project teams supporting the setup, maintenance, integration, quality control, and closure of clinical trial systems. The role involves client and vendor coordination, technical documentation review, CRF quality review, timeline and budget tracking, system integration oversight, sales support, and internal user acceptance testing. Candidates need clinical data management experience, relational database knowledge, data flow diagramming skills, project management capabilities, protocol interpretation expertise, strong communication skills, and a bachelor's degree.

Lead clinical adjudication projects for pharmaceutical and CRO studies, coordinating charter development, workflow optimization, endpoint training, reference guides, project plans, milestones, metrics, and cross-functional meetings. Monitor progress, resolve roadblocks, and support timely, budget-conscious, high-quality delivery. The role requires experience in outcomes adjudication, patient enrollment and retention, preferably in late-phase cardiovascular studies, along with knowledge of ICH/GCP and regulatory guidelines.