Bioinformatician I, II, III (ADX-92-20)

| Greater Boulder Area
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Bioinformatician I, II, III (ADX-92-20)

THE COMPANY: ArcherDX, Inc. -


ArcherDX is advancing molecular diagnostics with a robust technology platform for genetic mutation detection by next-generation sequencing. By combining patented Anchored Multiplex PCR (AMP™) chemistry in an easy-to-use, lyophilized format and powerful bioinformatics software, the Archer® platform enhance genetic mutation identification. ArcherDX provides oncology-focused research products and is pursuing regulatory approval for multiple companion diagnostic assays. ArcherDX is headquartered in Boulder, Colorado. Learn more at and follow @ArcherDXInc on Twitter, Facebook and LinkedIn. 

The primary role of this position is to engineer maintainable and well-tested tools for genomic sequence data analysis while adhering to ArcherDX software engineering methodologies. The bioinformatician will create novel tools, customize existing ArcherDX and third party tools in order to improve and accommodate new and existing applications of ArcherDX products.
The bioinformatician will work closely with molecular biologists to analyze and interpret the results of laboratory experiments and will be able to provide guidance on how to best design their experiments. This individual will elicit requirements from the Molecular Biology team in order to build tools that will facilitate assay optimization and new product development. Assay optimization and new product development will involve determining the best assay parameters by applying and interpreting statistical analysis of the data and by creating rich visualizations of the data. It will also involve novel algorithm creation via rapid prototyping followed by rigorous testing to show the viability of new concepts.
  • Exploratory analysis that facilitates data driven decisions
    • Analysis built to be reproducible and extended for new problems
    • Reports that tell a story about the data and draws conclusions
    • Presentations that are easily digestible by molecular biologists 
  • Data analysis and visualization
    • Rich figures and tables that show complex data simply
  • Algorithm testing, optimization and development
    • Use of statistical modeling, machine learning and bioinformatics to create highly sensitive and specific algorithms for the detection of genomic aberrations in NGS data
  • Design scalable, maintainable and well tested commercial grade software
    • Use and refine agile-like processes in order to produce high quality software
  • Follow team policies for producing both ad-hoc analysis and commercial software
    • Show discipline in adhering to team adopted processes 
  • Review, understanding, and compliance with ArcherDX HIPAA Security policies and procedures.
  • Safeguarding the privacy and security of protected health information and European Union personal data.
  • Processing and handling of European Union personal data only as directed by ArcherDX for purposes of personalized molecular pathology.
  • Additional duties as assigned
  • 0-6 years of bioinformatics experience
    • Experience, education and skill set will determine title and compensation
  • Understand the basics of molecular biology as it pertains to human disease, primarily in cancer
  • Proficiency with Python (or any object-oriented language) and standard NGS bioinformatics tools (e.g. GATK, BOWTIE, BWA, etc.)
    • Additional experience with lower level languages like C++ and C are a plus
  • Ability to design, create and query relational databases (No-SQL experience a plus)
  • Machine learning in NGS applications
  • Proficiency with iPython notebook is a plus
  • Proficiency in statistics is a plus
  • Formal software development experience is plus
  • Proficiency in object oriented design principals is a plus
  • Understanding of FDA regulations for software development in medical devices is a plus
*The candidate as a whole will be evaluated and strengths in one area may make up for lack of experience in others
  • Insatiable curiosity
  • Introspective and self-aware
  • Humble
  • Healthy dose of insecurity that leads to data driven decisions
  • Relies on data more than gut instinct
  • Puts the team harmony over their own self-interest
    • Puts data above all
  • Disciplined in following process consistently
  • BS/MS/PhD in bioinformatics, computer science or related field and/or equivalent combination of education and experience
This job description is not designed to cover nor contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities and activities may change at any time with or without notice.
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Technology we use

  • Engineering
    • JavascriptLanguages
    • PythonLanguages
    • RLanguages
    • D3JSLibraries
    • jQuery UILibraries
    • Twitter BootstrapLibraries
    • DjangoFrameworks
    • PostgreSQLDatabases


Conveniently located minutes from downtown Boulder via Pearl Street or the Goose Creek Path. Easily commutable from all directions.

An Insider's view of ArcherDX

What’s the vibe like in the office?

Collaborative - when I walk through the ArcherDX office at any time of day, I can see cross-functional collaboration in action. Our team members are constantly connecting in structured and unstructured meetings to solve problems and achieve goals.


Corporate Recruiter

How do you collaborate with other teams in the company?

Collaboration between functional groups is key to the Logistics team's success at Archer. Working closely with Sales, Manufacturing, Assay Development, Customer Support, Finance and QA allows us to provide better customer service by improving our processes, troubleshoot, brainstorm new ideas, learn from each other and share our best "dad" jokes.


Logistics Manager

How do you empower your team to be more creative?

Creativity requires a break from the routine and the screen. Here at Archer the team gets creative through walks to the food trucks, lunch runs, climbing gym sessions or a few end of the week craft brews. Some of our best algorithms were developed or refined on the climbing gym mat.


VP of Bioinformatics and Commercial Development

How do your team's ideas influence the company's direction?

The marketing team brings in and drives the voice of our customers across the organization. Each strategic decision we make at ArcherDX is informed by a deep, customer-centric approach, where we use our insights to better understand how we can deliver an exceptional experience and aim to positively impact the lives of the patients we serve!


Director, Global Marketing

What are ArcherDX Perks + Benefits

ArcherDX Benefits Overview

ArcherDX offers a competitive and generous benefit package including:

• Medical PPO or HMO and Dental-82% of monthly premium covered by the company
• Optional vision, life, FSA, dependent care plans
• Basic AD&D, Short and Long Term disability-covered 100% by the company
• 160 hours PTO per calendar after three months of service
• 6-weeks parental leave covered 100% by the company
• 401K with company match with potential of up to $2000/year
• 2019 bonus - 5% based on company objectives (for non-commissioned employees)
• Company stock options for all employees
• Tuition Reimbursement
• Ecopass

Volunteer in local community
Partners with Nonprofits
Friends outside of work
Eat lunch together
Daily stand up
Open door policy
Team owned deliverables
Team based strategic planning
Group brainstorming sessions
Documented equal pay policy
Health Insurance & Wellness Benefits
Flexible Spending Account (FSA)
Disability Insurance
Dental Benefits
Vision Benefits
Health Insurance Benefits
Life Insurance
Wellness Programs
Retirement & Stock Options Benefits
401(K) Matching
Company Equity
Child Care & Parental Leave Benefits
Generous Parental Leave
Remote Work Program
Our remote work program includes work from home on occasion as needed.
Family Medical Leave
Employees who have been with the company for 12 months are eligible for 12 weeks of family medical leave.
Company sponsored family events
Archer sponsors family oriented events annually. This year, we had our summer picnic at the Boulder Reservoir.
Vacation & Time Off Benefits
Generous PTO
Paid Holidays
Perks & Discounts
Beer on Tap
Casual Dress
Commuter Benefits
Company Outings
Archer hosts company outings Semi-annually.
Relocation Assistance
Professional Development Benefits
Job Training & Conferences
Tuition Reimbursement
Our tuition reimbursement plan offers an annual max of $5250.
Cross functional training encouraged
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