Bioinformatics Engineer, Algorithm

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Invitae is a healthcare technology company that leverages genetic information to empower doctors and patients to make informed medical decisions. Our development team works on a variety of projects ranging from innovations in healthcare systems to taming the chaos of biology. We are constantly improving our tools and technologies to deliver the highest quality actionable information to doctors and patients. Behind every sample that comes in through the door we know there is an individual and a family looking for answers.As part of our bioinformatics modeling and algorithms team, you will help ensure our methods and tools are of the highest caliber. Frequently in the team, you will own the problem from conception to release and help drive execution by convincing key stakeholders with data. You will apply your knowledge of computer science, statistics, and NGS to analyze, improve, and develop techniques and algorithms for calling genetic events across an expanding set of modern assays. You will work and learn among an extraordinary set of peers: bioinformaticians, molecular biologists, and software engineers. Your work will directly improve the quality of our product and positively impact each tested patient.What you will do:
  • Build and evaluate algorithms and statistical models to improve existing genetics applications within and beyond NGS technologies and create novel ones
  • Drive genetics technology development in a cross-disciplinary setting by critically analyzing and deriving insights from experimental data (including NGS, arrays, and novel technologies) using open source NGS tools and building custom tools when needed
  • Working with wet lab scientists to independently design experiments and communicate conclusions for internal review
  • Develop reproducible analysis for research and development purposes
What you will bring:
  • Advanced graduate degree in bioinformatics, statistics, computer science or a related discipline, or 5+ years of experience working in a bioinformatics role
  • Have deep knowledge and experience analyzing genetics data including NGS and/or arrays, either from industry or academia
  • Familiarity or experience with NGS Primary analysis (image processing, machine learning, quality metrics) is a plus
  • Understand the detailed statistical and algorithmic workings of modern variant calling packages (preferably GATK)
  • Comfortable reading source code for large open source projects with preference for Python
  • Excellent communication (written and verbal) and data presentation skills
  • Preferred: PhD in bioinformatics, statistics, computer science or a related discipline, or 7+ years working in bioinformatics role
  • Preferred: Candidates with working experience with somatic or low input DNA assays

At Invitae, we value diversity and provide equal employment opportunities (EEO) to all employees and applicants without regard to race, color, religion, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. We will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of the San Francisco Fair Chance Ordinance.

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Technology we use

  • Engineering
    • C++Languages
    • JavascriptLanguages
    • PythonLanguages
    • RLanguages
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    • SqlLanguages
    • D3JSLibraries
    • jQuery UILibraries
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    • MongoDBDatabases
    • PostgreSQLDatabases

Location

Conveniently located minutes from downtown Boulder via Pearl Street or the Goose Creek Path. Easily commutable from all directions.

An Insider's view of Invitae (Formerly ArcherDx)

What’s the vibe like in the office?

Collaborative - when I walk through the Invitae office at any time of day, I can see cross-functional collaboration in action. Our team members are constantly connecting in structured and unstructured meetings to solve problems and achieve goals.

Sarah

Corporate Recruiter

How do you collaborate with other teams in the company?

Collaboration between functional groups is key to the Logistics team's success at Invitae. Working closely with Sales, Manufacturing, Assay Development, Customer Support, Finance and QA allows us to provide better customer service by improving our processes, troubleshoot, brainstorm new ideas, learn from each other and share our best "dad" jokes.

Judy

Logistics Manager

How do you empower your team to be more creative?

Creativity requires a break from the routine and the screen. Here at Archer the team gets creative through walks to the food trucks, lunch runs, climbing gym sessions or a few end of the week craft brews. Some of our best algorithms were developed or refined on the climbing gym mat.

Aaron

VP of Bioinformatics and Commercial Development

What are Invitae (Formerly ArcherDx) Perks + Benefits

Invitae (Formerly ArcherDx) Benefits Overview

At Invitae, our employees are the key to our continued success. Our culture is one of our most important strengths. A set of commitments we make to each other and to our customers to build a world-class organization in service of our mission. That is why Invitae proudly offers comprehensive perks and benefits program with choice and flexibility in mind.

Culture
Volunteer in local community
Friends outside of work
Eat lunch together
Intracompany committees
Daily sync
Open door policy
Team owned deliverables
Team based strategic planning
Group brainstorming sessions
Open office floor plan
Diversity
Dedicated Diversity/Inclusion Staff
Highly diverse management team
Unconscious bias training
Diversity manifesto
Someone's primary function is managing the company’s diversity and inclusion initiatives
Mean gender pay gap below 10%
Diversity Employee Resource Groups
Hiring Practices that Promote Diversity
Health Insurance & Wellness Benefits
Flexible Spending Account (FSA)
Disability Insurance
Dental Benefits
Vision Benefits
Health Insurance Benefits
Life Insurance
Pet Insurance
Wellness Programs
Team workouts
Mental Health Benefits
Retirement & Stock Options Benefits
401(K)
401(K) Matching
Company Equity
Employee Stock Purchase Plan
Performance Bonus
Child Care & Parental Leave Benefits
Generous Parental Leave
Flexible Work Schedule
Remote Work Program
Our remote work program includes work from home on occasion as needed.
Family Medical Leave
Restricted work hours
Return-to-work program post parental leave
Vacation & Time Off Benefits
Unlimited Vacation Policy
Generous PTO
Paid Holidays
Paid Sick Days
Perks & Discounts
Beer on Tap
Casual Dress
Commuter Benefits
Company Outings
Archer hosts company outings Semi-annually.
Happy Hours
Relocation Assistance
Professional Development Benefits
Job Training & Conferences
Tuition Reimbursement
Our tuition reimbursement plan offers an annual max of $5250.
Diversity Program
Lunch and learns
Cross functional training encouraged
Promote from within
Mentorship program
Time allotted for learning
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