Bioinformatics Associate (Clinical Services) (ADX-35-20) at ArcherDX
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Bioinformatics Associate (Clinical Services) (ADX-36-20)
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THE COMPANY: ArcherDX, Inc. - www.ArcherDX.com
ArcherDX is advancing molecular diagnostics with a robust technology platform for genetic mutation detection by next-generation sequencing. By combining patented Anchored Multiplex PCR (AMP™) chemistry in an easy-to-use, lyophilized format and powerful bioinformatics software, the Archer® platform enhance genetic mutation identification. ArcherDX provides oncology-focused research products and is pursuing regulatory approval for multiple companion diagnostic assays. ArcherDX is headquartered in Boulder, Colorado. Learn more at www.archerdx.com and follow @ArcherDXInc on Twitter, Facebook and LinkedIn.
POSITION SUMMARY:
The primary role of this position is to engineer maintainable and well-tested tools for genomic sequence data analysis while adhering to ArcherDX software engineering methodologies. The bioinformatics associate will create novel tools, customize existing ArcherDX and third party tools in order to improve and accommodate new and existing applications of ArcherDX products.
The bioinformatics associate will work closely with molecular biologists to analyze and interpret the results of laboratory experiments and will be able to provide guidance on how to best design their experiments. This individual will elicit requirements from the Molecular Biology team in order to build tools that will facilitate assay optimization and new product development. Assay optimization and new product development will involve determining the best assay parameters by applying and interpreting statistical analysis of the data and by creating rich visualizations of the data. It will also involve novel algorithm creation via rapid prototyping followed by rigorous testing to show a proof of new concepts.
As necessary, but not as a primary role, assist the Clinical team in ad-hoc analysis and research required to meet regulatory requirements.
RESPONSIBILITIES:
Job performance will involve a variety of activities including:
- Algorithm development in sequence analysis and quantitative data analysis
- Exploratory ad-hoc analysis of experiments
- Data analysis and visualization
- Algorithm testing and optimization
- Design scalable, maintainable and well tested commercial grade software
- Additional duties as assigned
- Follow team policies for producing both ad-hoc analysis and commercial software
- Review, understanding, and compliance with ArcherDX HIPAA Security policies and procedures.
- Safeguarding the privacy and security of protected health information and European Union personal data.
- Processing and handling of European Union personal data only as directed by ArcherDX for purposes of personalized molecular pathology.
EXPERIENCE:
- 2+ years of bioinformatics experience
- Proficiency with python and standard bioinformatics tools (e.g. GATK, bowtie, bwa, etc)
- Formal statistics background is a plus
- Formal software development experience (preferred)
KEY ATTRIBUTES:
- Drive and determination
- Demonstrated scientific problem solving skills
- Ability to participate with others as a member of the team to ensure that demanding projects are handled smoothly and cooperatively to enhance success of project and maintain strong relationships within all parts of company
- Strong communication and presentation skills
- Proven ability to thrive in a start-up/change oriented environment
- Self Starter
- Driven to perform
- Self-directed: needs little explicit direction and no hand-holding
- Able to organize and prioritize a diverse set of responsibilities to ensure that focus on growth and success of company is achieved
EDUCATION:
- BS/MS/PhD in bioinformatics, computer science or related field and/or equivalent combination of education and experience
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